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The gift from Allen and Charlotte Ginsburg will establish a research fund at the USC Institute for Biomedical Therapeutics. (Photo courtesy of Allen and Charlotte Ginsburg)

Gift supports biomedical innovation at USC

A $10 million gift from Allen and Charlotte Ginsburg will provide critical funding for innovative research at USC into debilitating neurosensory diseases.

Kella Vangsness (Photo by Cristy Lytal)

USC’s Kella Vangsness paints stem cells as superheroes

With captions by Kella Vangsness “As an artist and scientist, I cannot help but imagine stem cells as ‘superheroes’ fighting against ‘villains’ of disease,” said Kella Vangsness, who is graduating from USC …

Synapses in the mammalian cochlea (Image courtesy of Juemei Wang)

Simple treatment may minimize hearing loss triggered by loud noises

It’s well known that exposure to extremely loud noises — whether it’s an explosion, a firecracker or even a concert — can lead to permanent hearing loss. But knowing how to treat …

Tubular networks developing in a mammalian kidney (Image by Tracy Tran/Andy McMahon Lab)

Growing hope: What are stem cells, and how does USC use them?

Stem cell therapies have accelerated at a promising pace, but how do they work? And what are stem cells?

Justin Ichida (Photo by Ben Gibbs)

USC Stem Cell scientist Justin Ichida named inaugural Richard N. Merkin Scholar

In USC’s Department of Stem Cell Biology and Regenerative Medicine, half of the faculty members are assistant professors, poised at the threshold of their careers in biomedical research. One of these promising …

Retinal pigment epithelial cells (Image courtesy of David Hinton)

Researchers test stem cell–based retinal implant for common cause of vision loss with encouraging results

Physicians and researchers at the USC Roski Eye Institute have collaborated with other California institutions to show that a first-in-kind stem cell–based retinal implant is feasible for use in people with advanced …

Surgeons perform a breakthrough one-time treatment to replace a defective gene with a healthy copy made from artificial DNA. (Photo courtesy of CHLA)

Physicians use gene therapy to restore patient’s vision

Surgeons of The Vision Center at Children’s Hospital Los Angeles completed a revolutionary gene replacement procedure at 9:20 a.m. March 20, to restore vision in a patient with retinal degeneration, using the …

From left, stem cell researchers Andres Matias Lebensohn, Maxwell Z. Wilson, Seth Shipman, Pulin Li and Yejing Ge (Photo by Cristy Lytal)

At USC’s Junior Faculty Mini-Symposium, stem cell scientists build to understand

When physicist Richard Feynman died in 1988, he left a message scrawled across his chalkboard: “What I cannot create, I do not understand.” Twenty years later, scientists in a very different field …

Genetic and lifestyle factors could play a role in developing Alzheimer’s disease, researchers say. (Photo courtesy of Stocksy)

Five ways to lower your chances of getting Alzheimer’s

Retain a sharp, healthy brain and reduce your risk of Alzheimer’s disease by following five simple rules. Some of the tips are scientifically proven, while others show promise but require further investigation.

Paula Cannon (Photo by Don Milici)

Paula Cannon and Elyn Sacks named Distinguished Professors

Paula Cannon, PhD, and Elyn Saks, PhD, JD, have been named Distinguished Professors by USC President C. L. Max Nikias. USC Provost Michael Quick, PhD, announced the appointments in a Feb. 13 …

Motor nerve cells (Image courtesy of the Ichida Lab)

The toxic relationship between ALS and frontotemporal dementia

ALS and frontotemporal dementia (FTD) are two neurodegenerative diseases with a toxic relationship, according to a new USC Stem Cell study published in Nature Medicine.

Diffusion MRI maps show disrupted white matter connectivity and loss of white matter fiber tracts in 1 year-old pericyte-deficient mice. (Image courtesy of the Zlokovic Lab)

Half of all dementias start with damaged “gatekeeper cells”

USC research sheds new light on how a breakdown in the brain’s vascular system predates the accumulation of toxic plaques and tangles in the brain that bring about Alzheimer’s disease. The research …

Valter Longo (Photo by John Skalicky)

What to know about fasting, aging, the “longevity diet” and when you should eat

Biochemist Valter Longo has devoted decades to discovering connections between nutrition and successful aging. He runs the Longevity Institute at the USC Leonard Davis School of Gerontology, which aims to extend healthy …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology)

Bérénice Benayoun studies possibility of rejuvenating genes

Bérénice Benayoun, assistant professor at the USC Leonard Davis School of Gerontology and principal investigator with USC Stem Cell, explores the role of epigenetics—the ways that genes turn “off” or “on”—in the …

Synapses between nerve cells, called neurons, and muscle cells in the fruit fly Drosophila are giving clues to how neurons maintain communication. Here, a synapse is immunostained with antibodies that recognize the neuronal membrane (blue), active zones (green) and neurotransmitter receptors (red). (Image courtesy of Dion Dickman)

Answers for diseases like schizophrenia may lie in how the brain maintains balance

Pop psychologists tout “balance” as key to mental health, and they may be more right than they realize. Neuroscientist Dion Dickman is gaining insight into how the brain maintains healthy balance on …

Abigail Zamora

Broad Clinical Research Fellows use stem cells to build bone and combat cancer

This year’s Broad Clinical Research Fellows will apply stem cell-based approaches to two prevalent problems: non-healing bone injuries, which affect 5 million Americans each year; and neuroblastoma, which is the most common …

Michaela Patterson (Photo by Cristy Lytal)

Broad Fellows look to stem cells to treat heart disease and hearing loss

When it came time to select this year’s Broad Fellow, the award committee couldn’t pick just one. Instead, they bestowed the honor on two talented postdoctoral researchers in USC Stem Cell laboratories: …

Embryonic stem cells (Image/courtesy of Qi-Long Ying)

Subtle cues can dictate the fate of stem cells

If you’ve seen one GSK3 molecule, do not assume that you have seen them all. A new study in Developmental Cell reveals important differences in two similar forms of GSK3, which, in …

Embryonic mouse cortex with neural stem cells (red) and neurons (green) (Image by Wen-Hsuan Chang/Wange Lu Lab)

Ryk needs a chaperone

Ryk has made the headlines by requiring a chaperone. But don’t assume that Ryk is a badly behaved celebrity—it’s actually a protein featured in a new study in the Proceedings of the …

From left, Gio Suh and Lauren Ekman (Photo by Cristy Lytal)

Countdown to Commencement: Gio Suh builds muscles without exercising

“I’ve always wanted to be in a textbook and impact the world,” said Gio Suh, who is graduating in December 2017 from the master of science program in stem cell biology and …