Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs its digestive and metabolic systems, including the liver, pancreas and digestive tract. They are also developing new regenerative treatments for patients with diabetes, metabolic syndromes, inflammatory bowel diseases, short bowel syndrome, hepatitis, liver fibrosis, liver cancer, colon cancer and many other diseases.

Statistics

  • Nearly 10 percent of Americans—more than 30 million people—have diabetes, which is the seventh leading cause of death in the US.
  • Inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease, affect 1.6 million Americans.
  • Approximately 4.3 percent of people will be diagnosed with colorectal cancer in their lifetimes. Colorectal cancer affects more than 1.3 Americans, and is the second leading cause of cancer-related death in the US.
  • More than 40,000 Americans are diagnosed with liver cancer each year. Nearly 30,000 Americans die from liver cancer each year.
  • Worldwide, 500 million people have hepatitis B or C. These viruses kill 1.5 million people a year.

Researchers

Digestion and Metabolism News

A circular field of cells shows a gradient of patterns, with green spots decreasing in size as cell density increases.

By exerting “crowd control” over mouse cells, scientists make progress towards engineering tissues

Genes aren’t the sole driver instructing cells to build multicellular structures, tissues, and organs. In a new paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist …

From right, Dean Carolyn Meltzer, Senta Georgia, and Charles (Chuck) Murry (Photo courtesy of Charles (Chuck) Murry)

Keck School of Medicine celebrates faculty achievements at annual awards ceremony

The 2024 Faculty Awards and Recognition Ceremony was a night of recognition and reflection as Dean Carolyn C. Meltzer, the Keck School Faculty Council and the Office of Faculty Affairs, Advancement, and …

Charles (Chuck) Murry (Photo by Gavin Sisk/ University of Washington)

USC Stem Cell welcomes new leader, renowned physician-scientist Chuck Murry

Charles (Chuck) Murry, MD, PhD, has been appointed as the next head of USC Stem Cell. In that capacity, he will be the chair of the Department of Stem Cell Biology and …

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Digestion and Metabolism Videos

To discover new therapies to treat disease, scientists use living cells to study drug action and identify new drug candidates. The Choi Family Therapeutic Screening Facility in USC’s stem cell research center uses robotic systems that can simultaneously conduct thousands of tests of drug-like molecules in a “high-throughput screen” process designed to give insight into new therapies to treat many types of disease.
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