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Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and regenerates the heart, lungs and blood. They are also developing new regenerative treatments for the millions of patients with diseases of the heart, lungs, immune system and blood.

Statistics

  • Heart disease is the leading cause of death worldwide. In the US every year, about 610,000 people die of heart disease—the cause of one in four deaths.
  • An estimated 1.29 million people in the US are living with or in remission from blood cancer—leukemia, lymphoma or myeloma.
  • Globally, 36.7 million people are living with the autoimmune disease HIV, and 1.8 million of these are children. An estimated 35 million people have died from HIV-related causes so far.
  • More than 30,000 people in the US and 70,000 worldwide are living with the inherited lung disease cystic fibrosis, which limits the ability to breathe.

Researchers

Heart, Lung and Blood News

Kuo-Chang (Ted) Tseng from the Crump Lab and Michelle Hung from the Ichida Lab enjoy a beachside brainstorm.

Scientists feel the sand between their toes at the retreat for USC’s stem cell department

A pair of young scientists picked up a piece of driftwood and thoughtfully traced a series of letters in the wet sand of Ventura Beach. The word “microglia”—referring to the immune cells …

USC and CHLA awarded $8 million to expand access to cell and gene therapy clinical trials

The California Institute for Regenerative Medicine (CIRM), the state’s stem cell agency, has awarded a five-year, $8 million grant to the Keck School of Medicine of USC and Children’s Hospital Los Angeles (CHLA). …

A cell showing the enzyme BirA*G3, which tags the proteins of the "secretome" (Image courtesy of the McMahon Lab)

This mouse can’t keep a secret about the “secretome”

The “secretome” refers to proteins that are secreted by a cell, a tissue or an organism. In a new study published in Open Biology, USC Stem Cell scientist Andy McMahon and his …

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Heart, Lung and Blood Videos

To discover new therapies to treat disease, scientists use living cells to study drug action and identify new drug candidates. The Choi Family Therapeutic Screening Facility in USC’s stem cell research center uses robotic systems that can simultaneously conduct thousands of tests of drug-like molecules in a “high-throughput screen” process designed to give insight into new therapies to treat many types of disease.
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