Three USC researchers win $4.3 million in awards from California’s stem cell agency

Three scientists from Keck Medicine of USC have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine (CIRM) for research that includes creating a temporary liver for patients, finding novel ways to treat immune disorders and blood diseases, and developing new animal models for heart failure, diabetes and neurodegenerative diseases. The grants, …

At the retreat for USC’s stem cell department, the students become the masters

Students and trainees took center stage at the annual retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. They presented their latest research to the 180 stem cell scientists who gathered at the event, held at the Pala Mesa Resort in Fallbrook, California this September.

Ryk needs a chaperone

Ryk has made the headlines by requiring a chaperone. But don’t assume that Ryk is a badly behaved celebrity—it’s actually a protein featured in a new study in the Proceedings of the National Academy of the Sciences (PNAS).

Scientists get into detail at the retreat for USC’s stem cell department

“The process of disease is about detail,” said Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. Held on October 20 and 21 at the Pala Mesa Resort in Fallbrook, California, the …

USC’s stem cell scientists secure the dollars to fight disease

The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous grants to support stem cell-based approaches to study and treat illnesses ranging from osteoarthritis to Alzheimer’s disease to cystic fibrosis. Here are a …

What I’m reading: Top picks from stem cell faculty

Our genetic material is packed into the nucleus of the cell, but is the packing process random or organized in some way? In a recent study published in Cell Stem Cell, Krijger et al. showed predictable 3D arrangements of chromosomal regions in the nucleus.

Halloween retreat showcases USC’s “scary smart” stem cell researchers

It was no tricks and all treats at the seventh annual retreat for the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, held at the university’s Davidson Conference Center on Halloween. Center Director Andy McMahon welcomed nearly 100 researchers and encouraged them to mingle and get to “know at …

USC researchers apply brainpower to understanding neural stem cell differentiation

How do humans and other mammals get so brainy? USC researcher Wange Lu, PhD, and his colleagues shed new light on this question in a paper published in Cell Reports on October 24. The researchers donned their thinking caps to explain how neural stem and progenitor cells differentiate into neurons and related cells called glia. …

USC study sheds light on stem cell reprogramming

Researchers are learning how to turn regular cells into stem cells, a process called reprogramming. However, some of the mechanisms of the process remain unknown, such as why only a small proportion of the cells can be reprogrammed. Researchers have at least part of the answer: the structure of genes.

Unraveling the mystery of pluripotency in embryonic stem cells

Using advanced sequencing technology, Center faculty Wange Lu’s group, in collaboration with Dr. Kai Wang of Zilkha Neurogenetics Institute explores the mystery of pluripotency by mapping out the interaction between DNA elements using genetic loci of two important pluripotency genes OCT4 and SOX2. Their finding shows that chromosome elements can interact transiently and dynamically with …

Keck School researchers to speak at World Stem Cell Summit

Faculty researchers and clinicians from the Keck School of Medicine of USC are among more than 170 speakers who will discuss their efforts to zero in on disease cures at an international conference organized to highlight the progress of stem cell research. The World Stem Cell Summit 2011 takes place Oct. 3–5 at the Pasadena …

Wange Lu, PhD

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