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Digestion and Metabolism

Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs its digestive and metabolic systems, including the liver, pancreas and digestive tract. They are also developing new regenerative treatments for patients with diabetes, metabolic syndromes, inflammatory bowel diseases, short bowel syndrome, hepatitis, liver fibrosis, liver cancer, colon cancer and many other diseases.

Statistics

  • Nearly 10 percent of Americans—more than 30 million people—have diabetes, which is the seventh leading cause of death in the US.
  • Inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease, affect 1.6 million Americans.
  • Approximately 4.3 percent of people will be diagnosed with colorectal cancer in their lifetimes. Colorectal cancer affects more than 1.3 Americans, and is the second leading cause of cancer-related death in the US.
  • More than 40,000 Americans are diagnosed with liver cancer each year. Nearly 30,000 Americans die from liver cancer each year.
  • Worldwide, 500 million people have hepatitis B or C. These viruses kill 1.5 million people a year.

Researchers

News

Eli and Edythe Broad to receive honorary degrees at USC commencement ceremony

USC will recognize philanthropists Edythe and Eli Broad and five other honorary degree candidates for their leadership in government, science, philanthropy, humanitarianism and the arts at the university’s 136th commencement ceremony on the University Park Campus on May 10.

Fasting-mimicking diet holds promise for treating people with inflammatory bowel disease, USC study finds

What if a special diet could reduce inflammation and repair your gut? USC researchers provided evidence that a low-calorie “fasting-mimicking” diet has the potential to do just that. Published in the March 5 edition of Cell Reports, the study reports on the health benefits of periodic cycles of the diet for people with inflammation and …

Stem cell scientists take it one cell at a time at the Junior Faculty Candidate Mini-symposium

Cells should be treated as individuals, according to the scientists who presented research at the Junior Faculty Candidate Mini-symposium, hosted by USC’s Department of Stem Cell Biology and Regenerative Medicine on February 5. While cells have traditionally been evaluated as populations, these up-and-coming scientists shared their frontier approaches for studying the specific features and activities …

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Multimedia

The Choi Family Therapeutic Screening Facility enables investigators from USC and beyond to improve their understanding of diseases and accelerate the discovery of potential therapeutic drugs. (Video by Sergio Bianco)
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