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Digestion and Metabolism

Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs its digestive and metabolic systems, including the liver, pancreas and digestive tract. They are also developing new regenerative treatments for patients with diabetes, metabolic syndromes, inflammatory bowel diseases, short bowel syndrome, hepatitis, liver fibrosis, liver cancer, colon cancer and many other diseases.

Statistics

  • Nearly 10 percent of Americans—more than 30 million people—have diabetes, which is the seventh leading cause of death in the US.
  • Inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease, affect 1.6 million Americans.
  • Approximately 4.3 percent of people will be diagnosed with colorectal cancer in their lifetimes. Colorectal cancer affects more than 1.3 Americans, and is the second leading cause of cancer-related death in the US.
  • More than 40,000 Americans are diagnosed with liver cancer each year. Nearly 30,000 Americans die from liver cancer each year.
  • Worldwide, 500 million people have hepatitis B or C. These viruses kill 1.5 million people a year.

Researchers

News

Class of 2020

Meet three students from USC’s master’s program in stem cell biology and regenerative medicine

The 34 students in USC’s master’s program in stem cell biology and regenerative medicine have at least two things in common. First, they’re smart, with an average incoming GPA of 3.4. And second, they all seemed to enjoy the boba tea served at this year’s Student Orientation at the Eli and Edythe Broad CIRM Center …

USC finds new routes to industry engagement and funding

Story courtesy of In-Part Over the last year, Dr. Qing Liu-Michael, Program Director at USC Stem Cell and the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at the University of Southern California (USC), has been using IN-PART’s Discover service to find new streams of collaboration with companies proactively seeking academic …

Breakthrough in testosterone-producing cells could lead to treatment for “low T”

USC researchers have successfully grown human, testosterone-producing cells in the lab, paving the way to someday treat low testosterone with personalized replacement cells. In Monday’s Proceedings of the National Academy of Sciences, scientists describe how they transformed stem cells into functioning Leydig cells — the cells in the testes that produce the male sex hormone. “Our …

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Multimedia

The Choi Family Therapeutic Screening Facility enables investigators from USC and beyond to improve their understanding of diseases and accelerate the discovery of potential therapeutic drugs. (Video by Sergio Bianco)
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