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Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and regenerates the heart, lungs and blood. They are also developing new regenerative treatments for the millions of patients with diseases of the heart, lungs, immune system and blood.

Statistics

  • Heart disease is the leading cause of death worldwide. In the US every year, about 610,000 people die of heart disease—the cause of one in four deaths.
  • An estimated 1.29 million people in the US are living with or in remission from blood cancer—leukemia, lymphoma or myeloma.
  • Globally, 36.7 million people are living with the autoimmune disease HIV, and 1.8 million of these are children. An estimated 35 million people have died from HIV-related causes so far.
  • More than 30,000 people in the US and 70,000 worldwide are living with the inherited lung disease cystic fibrosis, which limits the ability to breathe.

Researchers

News

Neutrophil

Study highlights differences in immune cell function between male and female mice

A new USC study of a common, yet poorly understood type of white blood cell reveals the human immune cell’s response to pathogens differs greatly by sex and by age.  In this mouse study, males proved much more susceptible to a condition called sepsis than females. However, the scientists also found that the female disease-defense system is hardly perfect; their system changes with age to become nearly as harmful as the males’.    Those are the key findings in a study that appeared July 19, 2021 in Nature Aging.   …

Scott Fraser by Noe Montes

USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser is known for inventing new microscopes and other tools to observe living, developing embryos. But one of his lab’s most important pieces of technology filters coffee instead of light: it’s a restaurant-quality Espresso machine. “I wanted to make a place where people would come to steal coffee,” he said. “And …

Megan McCain and family

USC Professor Megan McCain crafts an approach to tissue engineering

Megan McCain has always liked using her hands to create things, ranging from art projects to human heart cells that grow on silicon chips. “I’ve always loved building things and doing crafts, which drew me to engineering,” said McCain, who was recently awarded tenure as an Associate Professor and the Chonette Early Career Chair in …

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The University of Southern California has designed a unique “incubator” for scientists, engineers and clinicians to collaborate across disciplines and leverage the transformative power of stem cells to develop the future of regenerative medicine. The USC Stem Cell incubator trains the next generation of scientists through a dedicated PhD program and first-of-its-kind master’s degree, and brings together leading researchers from around the world to gain insights into developmental biology and advance new treatments for human disease. Learn more at http://stemcell.keck.usc.edu.
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