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Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and regenerates the heart, lungs and blood. They are also developing new regenerative treatments for the millions of patients with diseases of the heart, lungs, immune system and blood.

Statistics

  • Heart disease is the leading cause of death worldwide. In the US every year, about 610,000 people die of heart disease—the cause of one in four deaths.
  • An estimated 1.29 million people in the US are living with or in remission from blood cancer—leukemia, lymphoma or myeloma.
  • Globally, 36.7 million people are living with the autoimmune disease HIV, and 1.8 million of these are children. An estimated 35 million people have died from HIV-related causes so far.
  • More than 30,000 people in the US and 70,000 worldwide are living with the inherited lung disease cystic fibrosis, which limits the ability to breathe.

Researchers

News

Leonardo Morsut

USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development

Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment. To begin unraveling this complexity, USC Stem Cell scientist Leonardo Morsut is designing artificial genetic programs to perturb natural signaling networks and study how this …

Xi Chen

For USC scientist Xi Chen, a chicken is more than just an egg’s way of making another egg

USC postdoctoral researcher Xi Chen knows that you have to break a few eggs in order to grow chicken stem cells. His work on maintaining embryonic stem cells (ESC) from chicken eggs provides insight into stem cell pluripotency and evolutionary developmental biology. “The choice of beginning with fertilized chicken eggs was critical to the success …

Lung organoids

USC scientist Ya-Wen Chen receives American Lung Association grant to advance stem cell-based lung therapies

USC Stem Cell scientist Ya-Wen Chen hopes to pioneer a new approach to regenerating damaged lung tissue, with support from a Catalyst Grant from the American Lung Association (ALA). The award provides $50,000 year for up to two years. “For many patients with chronic lung diseases, the only available treatment is transplantation—a difficult, dangerous surgery …

All Heart, Lung and Blood News

Multimedia

The University of Southern California has designed a unique “incubator” for scientists, engineers and clinicians to collaborate across disciplines and leverage the transformative power of stem cells to develop the future of regenerative medicine. The USC Stem Cell incubator trains the next generation of scientists through a dedicated PhD program and first-of-its-kind master’s degree, and brings together leading researchers from around the world to gain insights into developmental biology and advance new treatments for human disease. Learn more at http://stemcell.keck.usc.edu.
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