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Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs the muscles, cartilage and skeleton. They are also using stem cells to find new regenerative therapies for conditions ranging from difficult-to-heal bone fractures to muscle injury, from birth defects to arthritis.

Statistics

  • Arthritis and other rheumatoid conditions are the leading cause of disability in the US.
  • Approximately 6.3 million bone fractures occur each year in the US.
  • The most common fracture prior to age 75 is a wrist fracture. In those over age 75, hip fractures become the most common broken bone and can lead to permanent disability.
  • Between 10% and 55% of muscle injuries occur during sports activities.
  • Cleft lip and cleft palate are among the most common birth defects, affecting approximately one or two in a thousand babies.

Researchers

News

Pituitary fish

Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance to human health. But zebrafish have backbones like us, contain by and large the same types of …

Happy 10th Anniversary, BCC!

Happy 10th anniversary to USC’s stem cell research center

On October 29, 2010, we opened the doors of the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC. Today, on the 10th anniversary of the building’s grand opening, we reflect on a decade of progress in a celebratory video, featuring messages from everyone from USC President Carol Folt …

Pituitary fish

Pituitary puzzle gets a new piece, revising evolutionary history

Insights into century-old controversy about key gland’s development arise from research led by the Keck School of Medicine of USC A new USC-led study suggests a change to the developmental — and evolutionary — story of the pituitary gland. The pea-sized gland, nestled at the base of the brain, produces hormones that drive growth, aggression, …

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Multimedia

USC President Carol Folt, ALS patient activist and actress Renée Zellweger and others celebrate the 10th anniversary of the Eli and Edythe Broad Center for Regenerative Medicine (CIRM) and Stem Cell Research at USC.
All Muscles and Skeleton Videos

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