USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs the muscles, cartilage and skeleton. They are also using stem cells to find new regenerative therapies for conditions ranging from difficult-to-heal bone fractures to muscle injury, from birth defects to arthritis.


  • Arthritis and other rheumatoid conditions are the leading cause of disability in the US.
  • Approximately 6.3 million bone fractures occur each year in the US.
  • The most common fracture prior to age 75 is a wrist fracture. In those over age 75, hip fractures become the most common broken bone and can lead to permanent disability.
  • Between 10% and 55% of muscle injuries occur during sports activities.
  • Cleft lip and cleft palate are among the most common birth defects, affecting approximately one or two in a thousand babies.



Rat joints

Less common type of opioid may slow progression of osteoarthritis

A new animal model study  published in Arthritis & Rheumatology by Keck Medicine of USC researchers reveals that activating the kappa opioid receptor (KOR), a specific type of receptor in the body that binds to opioid-like compounds in the brain to alleviate pain, with a targeted drug can slow the progress of osteoarthritis without addiction …


What is the USC Ombuds?

Stress levels are running high with a pandemic, global recession, and social injustice threatening livelihoods and lives. While the USC Office of the Ombuds can’t resolve the world’s woes, it can serve as a confidential, impartial, informal, and independent problem-solving resource for students, faculty and staff. The University Ombuds—Thomas Kosakowski at the Health Sciences Campus, …

Yang Chai

Yang Chai appointed University Professor

Associate Dean of Research Yang Chai PhD ’91, DDS ’96 has been appointed a University Professor, making history as the first faculty member to achieve such distinction at the Ostrow School of Dentistry of USC. The designation, held by fewer than 20 other faculty members across the university, is awarded very selectively to those whose …

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The Choi Family Therapeutic Screening Facility enables investigators from USC and beyond to improve their understanding of diseases and accelerate the discovery of potential therapeutic drugs. (Video by Sergio Bianco)
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