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Muscles and Skeleton

Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs the muscles, cartilage and skeleton. They are also using stem cells to find new regenerative therapies for conditions ranging from difficult-to-heal bone fractures to muscle injury, from birth defects to arthritis.

Statistics

  • Arthritis and other rheumatoid conditions are the leading cause of disability in the US.
  • Approximately 6.3 million bone fractures occur each year in the US.
  • The most common fracture prior to age 75 is a wrist fracture. In those over age 75, hip fractures become the most common broken bone and can lead to permanent disability.
  • Between 10% and 55% of muscle injuries occur during sports activities.
  • Cleft lip and cleft palette are among the most common birth defects, affecting approximately one or two in a thousand babies.

Researchers

News

Stem cell scientists take it one cell at a time at the Junior Faculty Candidate Mini-symposium

Cells should be treated as individuals, according to the scientists who presented research at the Junior Faculty Candidate Mini-symposium, hosted by USC’s Department of Stem Cell Biology and Regenerative Medicine on February 5. While cells have traditionally been evaluated as populations, these up-and-coming scientists shared their frontier approaches for studying the specific features and activities …

NIH awards USC Stem Cell scientist Denis Evseenko $1.69 million to study arthritis and aging

What causes joints to age, lose their regenerative capacity and succumb to arthritis, and how can we slow this process? To address these questions, the National Institutes of Health have awarded a $1.69 million research project grant to investigator Denis Evseenko, associate professor of orthopaedic surgery and stem cell biology and regenerative medicine at the …

USC Stem Cell acquires two instruments to advance state-of-the-art cell sorting

When it comes to sorting cells or other small particles, there’s no better place to do so than USC. The university’s Flow Cytometry Facility recently acquired two top-of-the-line cell sorters, the BD FACSymphony and the BioRad S3e, thanks to generous support from several USC sources.

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Multimedia

As a USC oral surgeon and stem cell scientist, Dr. Yang Chai has dedicated more than 20 years to finding better ways to treat everything from cleft palate to tooth decay. In this interview, Dr. Chai discusses his research—as well as his recent election to the National Academy of Medicine.
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