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Muscles and Skeleton

Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs the muscles, cartilage and skeleton. They are also using stem cells to find new regenerative therapies for conditions ranging from difficult-to-heal bone fractures to muscle injury, from birth defects to arthritis.

Statistics

  • Arthritis and other rheumatoid conditions are the leading cause of disability in the US.
  • Approximately 6.3 million bone fractures occur each year in the US.
  • The most common fracture prior to age 75 is a wrist fracture. In those over age 75, hip fractures become the most common broken bone and can lead to permanent disability.
  • Between 10% and 55% of muscle injuries occur during sports activities.
  • Cleft lip and cleft palette are among the most common birth defects, affecting approximately one or two in a thousand babies.

Researchers

News

USC Stem Cell scientist Gage Crump gives a bare bones explanation of eLife skeletal development study

How do our skeletons form during embryonic development? To approach this question, PhD student Dion Giovannone, research scientist Sandeep Paul and the USC Stem Cell laboratory of Gage Crump looked to our not-so-distant relative: the tiny, transparent zebrafish. Crump explains their latest findings, published in eLife, about how embryonic cartilage transforms into adult bone. How …

Eli and Edythe Broad to receive honorary degrees at USC commencement ceremony

USC will recognize philanthropists Edythe and Eli Broad and five other honorary degree candidates for their leadership in government, science, philanthropy, humanitarianism and the arts at the university’s 136th commencement ceremony on the University Park Campus on May 10.

Stem cell scientists take it one cell at a time at the Junior Faculty Candidate Mini-symposium

Cells should be treated as individuals, according to the scientists who presented research at the Junior Faculty Candidate Mini-symposium, hosted by USC’s Department of Stem Cell Biology and Regenerative Medicine on February 5. While cells have traditionally been evaluated as populations, these up-and-coming scientists shared their frontier approaches for studying the specific features and activities …

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Multimedia

The Choi Family Therapeutic Screening Facility enables investigators from USC and beyond to improve their understanding of diseases and accelerate the discovery of potential therapeutic drugs. (Video by Sergio Bianco)
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