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(Image courtesy of iStock); featured image for USC team develops a powerful new analytical tool to advance CAR T cell therapy research

USC team develops a powerful new analytical tool to advance CAR T cell therapy research

The comprehensive analytical platform uses laser technology to analyze CAR T cells and has already revealed ways to optimize their manufacturing, including how to identify when CAR T cells are likely to …

USC biomedical engineers have harnessed focused ultrasound to improve CRISPR, a revolutionary tool that enables the DNA in living organisms to be modified. (Image byWang Lab and Pepper Workshop); featured image for New CRISPR toolkit to allow remote-controlled genome editing

New CRISPR toolkit to allow remote-controlled genome editing

USC Viterbi biomedical engineers harness focused ultrasound to revolutionize CRISPR’s capabilities to treat countless diseases. Thanks to CRISPR, our medical specialists will soon have unprecedented control over how they treat and prevent …

A circular field of cells shows a gradient of patterns, with green spots decreasing in size as cell density increases.; featured image for By exerting “crowd control” over mouse cells, scientists make progress towards engineering tissues

By exerting “crowd control” over mouse cells, scientists make progress towards engineering tissues

Genes aren’t the sole driver instructing cells to build multicellular structures, tissues, and organs. In a new paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist …

Paula Cannon, PhD, at the American Society of Gene and Cell Therapy 27th Annual Meeting in Baltimore.; featured image for USC scientist Paula Cannon takes the reins as president of the American Society of Gene and Cell Therapy

USC scientist Paula Cannon takes the reins as president of the American Society of Gene and Cell Therapy

Paula Cannon, a Distinguished Professor at the Keck School of Medicine of USC, heads the world’s largest organization devoted to developing next-generation therapies that address the underlying causes of disease. USC geneticist …

nurse visits with a patient; featured image for USC and CHLA awarded $8 million to expand access to cell and gene therapy clinical trials

USC and CHLA awarded $8 million to expand access to cell and gene therapy clinical trials

The California Institute for Regenerative Medicine (CIRM), the state’s stem cell agency, has awarded a five-year, $8 million grant to the Keck School of Medicine of USC and Children’s Hospital Los Angeles (CHLA). …

USC's stem cell research center

California’s biggest stem cell experiment: The impact of the stem cell ballot proposition at USC

In 2008, USC broke ground on an $80 million building dedicated solely to stem cell research and regenerative medicine. The plans called for a monolithic structure clad in black marble and reflective …

Paula Cannon; featured image for Gene therapy research for HIV awarded $14.6 million NIH grant

Gene therapy research for HIV awarded $14.6 million NIH grant

An HIV research program led by scientists at USC and the Fred Hutchinson Cancer Research Center has received a five-year, $14.6 million grant from the National Institutes of Health. The team is advancing …

Kalya Stanten; featured image for Countdown to Commencement: USC Stem Cell master’s student Kalya Stanten follows the science

Countdown to Commencement: USC Stem Cell master’s student Kalya Stanten follows the science

By following her love of science, USC master’s student Kalya Stanten has found herself in some very interesting places—including a virology lab at the outset of the COVID-19 pandemic. “I’m in Paula …

Tubular networks developing in a mammalian kidney (Image by Tracy Tran/Andy McMahon Lab); featured image for Growing hope: What are stem cells, and how does USC use them?

Growing hope: What are stem cells, and how does USC use them?

Stem cell therapies have accelerated at a promising pace, but how do they work? And what are stem cells?

Paula Cannon (Photo by Don Milici); featured image for Paula Cannon and Elyn Sacks named Distinguished Professors

Paula Cannon and Elyn Sacks named Distinguished Professors

Paula Cannon, PhD, and Elyn Saks, PhD, JD, have been named Distinguished Professors by USC President C. L. Max Nikias. USC Provost Michael Quick, PhD, announced the appointments in a Feb. 13 …

Senta Georgia in the lab; featured image for A revolution in genetics

A revolution in genetics

Courtesy of Children’s Hospital Los Angeles Adding a piece of DNA to treat diabetes A child develops a rare form of diabetes, due to the absence of a single piece of DNA …

Clockwise from top left: Andy McMahon, Rohit Varma, Jonathan Samet and Donna Spruijt-Metz (Photos courtesy of USC); featured image for NIH funding helps Americans live longer and healthier

NIH funding helps Americans live longer and healthier

The nation’s medical research agency, the National Institutes of Health, funds research to help Americans live longer and healthier. Some 148 Nobel Prize winners have received support from the NIH, demonstrating how …

3-D printed Cas9 enzyme that snips a DNA sequence at a location identified by CRISPR. (Photo courtesy of the NIH 3D Print Exchange, National Institutes of Health); featured image for USC Stem Cell scientists enter the conversation about CRISPR

USC Stem Cell scientists enter the conversation about CRISPR

CRISPR-Cas9 is a gene-editing technique that enables scientists to disable, replace or modify sections of DNA. It allows for unprecedented precision and speed in the field of genome editing. It has been used to …

Motor neurons derived from an ALS patient (Image courtesy of the Ichida Lab); featured image for USC announces winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards

USC announces winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards

Two collaborative teams within USC Stem Cell are developing new approaches that could eventually help patients with heart disease, frontotemporal dementia and amyotrophic lateral sclerosis (ALS). The teams are the winners of …

Paula Cannon (Photo by Don Milici); featured image for USC and Sangamo researchers advance genome editing of blood stem cells

USC and Sangamo researchers advance genome editing of blood stem cells

Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences. In an upcoming study in Nature Biotechnology, co-first authors Colin M. …

From right, Qi-Long Ying, director of the Chang Stem Cell Engineering Facility; Daniel Chang; Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC; and Cai Li Chang (Photo by Cristy Lytal); featured image for Chang Stem Cell Engineering Facility brings gene editing to USC and beyond

Chang Stem Cell Engineering Facility brings gene editing to USC and beyond

Once the stuff of science fiction, genetic engineering is now offered on a fee-for-service basis at USC. On September 19, USC Stem Cell faculty and staff welcomed their supporters, the Chang and …

From left, John Zaia, Dale Ando, David Hardy and Paula Cannon (Photo courtesy of the California Institute for Regenerative Medicine); featured image for The road to a cure for HIV/AIDS

The road to a cure for HIV/AIDS

Something wonderful sometimes happens when scientists and the public get together to talk about research. All the jargon, all the technical language falls away, and it becomes instead a conversation between the …

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC (Photo by Chris Shinn); featured image for Take a tour of USC’s stem cell research center

Take a tour of USC’s stem cell research center

Video by Alric Devotta Director Andy McMahon leads a tour of the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC.

Illustration of the HIV virus; featured image for CIRM-funded clinical trial aimed at blocking HIV/AIDS in people gets the go ahead

CIRM-funded clinical trial aimed at blocking HIV/AIDS in people gets the go ahead

An innovative therapy using a patient’s own stem cells, modified to resist infection with the AIDS virus, has been given approval by the Food and Drug Administration (FDA) to begin a clinical …

USC PhD student Louise Menendez examines the prototype of a potential device to treat patients with liver disease. (Photo by Cristy Lytal); featured image for “Million-dollar ideas” seminar

“Million-dollar ideas” seminar

At a special seminar on February 24, USC Stem Cell Principal Investigators discussed their “million-dollar ideas” for creating new tools and technologies to usher in the era of regenerative medicine. They shared …