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CIRM COMPASS Scholars 2026 (Photo by Cristy Lytal); featured image for CIRM grant renewal helps USC undergrads turn stem cell research into careers

CIRM grant renewal helps USC undergrads turn stem cell research into careers

$3.2 million award extends USC Stem Cell’s CIRM COMPASS workforce development program. The California Institute for Regenerative Medicine (CIRM) has awarded the Keck School of Medicine of USC a $3.2 million, 5-year …

Healthy growth plate; featured image for USC researcher probes the cells that sustain growth plates

USC researcher probes the cells that sustain growth plates

Assistant Professor Zhaoyang Liu hopes her research will not only help people with growth limitations but also advance the understanding of craniofacial biology. HOW DOES THE GROWTH PLATE — the region of …

Images of liver cells from aged rats elucidate cellular crosstalk in the liver. (Image by DeLeve Lab/USC); featured image for Treatment revives old liver cells in lab study, may help prevent Alzheimer’s and heart disease

Treatment revives old liver cells in lab study, may help prevent Alzheimer’s and heart disease

Keck School of Medicine of USC research in rats finds potential for treating diseases of aging via the liver and uncovers new insights about cell signaling. The liver’s job clearing harmful substances …

Star-shaped immature astroglia (red or green) identified in brain tissue surgically removed from patients with epilepsy. These cells increase in abundance with age and are associated with lower fluid intelligence. (Image by Aswathy Ammothumkandy/Bonaguidi Lab/USC Stem Cell); featured image for Immature brain support cells may be linked to human age-related cognitive decline

Immature brain support cells may be linked to human age-related cognitive decline

USC researchers studying human brain tissue found an association between abnormal immature astroglia, cells that play a supporting role in brain function, and lower reasoning ability in older adults with epilepsy. A …

Researchers in the lab; featured image for CHLA team discovers key pathway in heart lymphatic vessel development

CHLA team discovers key pathway in heart lymphatic vessel development

The findings could pave the way for better predicting lymphatic complications in children with single-ventricle heart disease. Researchers at Children’s Hospital Los Angeles have uncovered molecular signals that shape a little-understood network …

Knee injection; featured image for Clinical trial evaluates investigational injection for knee osteoarthritis

Clinical trial evaluates investigational injection for knee osteoarthritis

Keck Medicine of USC studies the safety of a USC-developed therapy and its potential effects on cartilage deterioration in the knee joint. Keck Medicine of USC has launched a clinical trial testing …

A lab-grown kidney organoid made of human collecting duct cells shows elongated tubules—the segment of the kidney primarily affected by the incurable genetic condition called autosomal recessive polycystic kidney disease (ARPKD). (Image by Carrie Zhang/Li Lab/USC Stem Cell); featured image for PKD Foundation provides support for kidney disease research by USC Stem Cell’s Zhongwei Li

PKD Foundation provides support for kidney disease research by USC Stem Cell’s Zhongwei Li

A two-year, $240,000 grant will back studies developing lab-made tissue to drive progress fighting an incurable genetic condition, autosomal recessive polycystic kidney disease. The PKD Foundation has awarded a two-year grant totaling …

Medical implant illustration; featured image for What If the device changing brain medicine was free for anyone to build?

What If the device changing brain medicine was free for anyone to build?

A USC Viterbi bioengineer’s implantable device that any researcher can use, modify, and build on is nearly ready for its first animal test. Getting here required reinventing not just the hardware, but …

Illustration of brain projection; featured image for There is no “brain x-ray.” A USC neurosurgeon-engineer is helping build better ones

There is no “brain x-ray.” A USC neurosurgeon-engineer is helping build better ones

A USC neurosurgeon and engineer argues that the tools to monitor the brain cheaply and without surgery are within reach — and that getting there requires putting engineers where patients actually are. …

Illustration of medical devices; featured image for Four innovators gather at USC to explore the devices changing medicine

Four innovators gather at USC to explore the devices changing medicine

Clinical translation was the stated theme of the biomedical devices and imaging session at the Alfred E. Mann Department of Biomedical Engineering‘s 50th anniversary symposium Sept. 3. The department, jointly part of …

Teeth with lesions; featured image for Think enamel erosion is irreversible? Think again.

Think enamel erosion is irreversible? Think again.

After decades of research, Ostrow faculty member Janet Moradian-Oldak prepares to bring a short peptide that can generate a biomimetic version of tooth enamel to market. FOR DECADES, PROFESSOR JANET MORADIAN-OLDAK has …

AI illustration of organoids on a petri dish; featured image for USC Ostrow earns new NIH grant to study head and neck cancers using human organoids

USC Ostrow earns new NIH grant to study head and neck cancers using human organoids

The R01 grant is the third such NIH award earned by Ostrow researcher and faculty member Dechen Lin, an accomplishment made all the more impressive given the extremely competitive funding environment. HEAD …

Lit-up tumor (Image/Midjourney); featured image for A new way to help CAR-T cells fight solid tumors could change cancer treatment

A new way to help CAR-T cells fight solid tumors could change cancer treatment

USC researchers developed a technique that uses focused ultrasound to temporarily “light up” solid tumors, giving cancer-fighting immune cells a target they can finally recognize. For more than a decade, CAR-T cell …

Chuck Murry in the lab; featured image for Heart health enters the future with a $28.7 million gift from the Marcus Foundation

Heart health enters the future with a $28.7 million gift from the Marcus Foundation

In a landmark moment for both the treatment of heart disease and philanthropic support, The Marcus Foundation has awarded the head of USC Stem Cell, Chuck Murry, MD, PhD, $28.7 million to …

Thymus; featured image for Thymus-derived hormone may help suppress age-related inflammation

Thymus-derived hormone may help suppress age-related inflammation

In animal models, researchers from the Keck School of Medicine of USC found that targeting the thymus can reduce age-related inflammation and improve cancer outcomes. Chronic, low-grade inflammation in the body—a phenomenon …

A breast cancer cell. (Image courtesy of the National Cancer Institute, National Institutes of Health); featured image for Finding a tumor’s soft spot to power-up immunotherapy

Finding a tumor’s soft spot to power-up immunotherapy

USC researchers have developed a new “black box” tool to measure the softness of tumor cells, an insight that could be crucial for more effective cancer treatment. Researchers at the USC Viterbi …

Researcher in the lab (Photo by Chris Shinn); featured image for Request for Applications: A.P. Giannini Foundation 2027 Postdoctoral Research Fellowship & Leadership Award

Request for Applications: A.P. Giannini Foundation 2027 Postdoctoral Research Fellowship & Leadership Award

A.P. Giannini, the founder of Bank of America, established the A.P. Giannini Foundation in 1945 to bring to fruition his long-held dream to promote the study and treatment of human diseases. Since …

Lab-grown kidney organoid (Image courtesy of the Lindström Lab); featured image for USC Stem Cell scientists engineer “synthetic organizer” cells to improve kidney organoids

USC Stem Cell scientists engineer “synthetic organizer” cells to improve kidney organoids

Mapping the human kidney, researchers discovered an unrecognized developmental axis and engineered “synthetic organizer” cells to recreate key developmental signals, producing improved, reproducible lab-grown organoids for studying disease and therapies. In a …

From left, John Oghalai and Brian Applegate with the cochleoscope (Photo by Cristy Lytal); featured image for USC startup receives up to $3.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop an inner ear imaging device

USC startup receives up to $3.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop an inner ear imaging device

AO Technologies, founded by USC researchers John Oghalai and Brian Applegate, has secured an ARPA-H small business award to develop a cochleoscope for clinical imaging of the inner ear. USC researchers John …

Engineered immune cells (red) attacking breast cancer cells (blue). The red cells are genetically engineered macrophages designed to selectively recognize, engulf and destroy breast cancer cells (blue), demonstrating a promising new cell-based immunotherapy approach. (Image by Shi Yue/Ying Lab); featured image for USC Stem Cell-led team creates a renewable cell source for cancer immunotherapy and beyond

USC Stem Cell-led team creates a renewable cell source for cancer immunotherapy and beyond

Researchers develop a way to grow and genetically engineer the progenitor cells that give rise to macrophages, a type of first-responder immune cell that shows promise for developing immunotherapies for cancers and …