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August 2015 cover of Cell

Researchers mimic viral infection in colon cancer stem cells

Researchers targeting colorectal cancer stem cells — the root cause of disease, resistance to treatment and relapse — have discovered a mechanism to mimic a virus and potentially trigger an immune response …

UKRO board and USC researchers in attendance included, from left, Edward Crandall, newly hired Director Kenneth Hallows, Nuria M. Pastor-Soler, Alicia McDonough, Laura Perin, Vito Campese and Janos Peti-Peterdi.

USC/UKRO Kidney Research Center opening is held

Keck School of Medicine of USC researchers recently joined board members from the University Kidney Research Organization (UKRO) to celebrate the opening of the USC/UKRO Kidney Research Center in the Mudd Memorial …

Motor neurons derived from an ALS patient (Image courtesy of the Ichida Lab)

USC Stem Cell researcher Justin Ichida receives $300,000 Muscular Dystrophy Association grant

Ten percent of all patients with two neurodegenerative diseases — frontotemperal dementia (FTD) and amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease — possess a mutation in the same gene. …

Age-related macular degeneration

Americans for Cures animates stem cell research at USC and UCSD

Americans for Cures produced a white board animation showcasing a clinical trial for age-related macular degeneration, led by USC Stem Cell researchers David Hinton and Mark Humayun:

Clockwise from top left: Andre Luis de Castro Abreu, Victoria Forte, Kathy Schall and Rodrigo Martínez Monedero (Photos by Cristy Lytal)

USC Stem Cell selects inaugural Broad Clinical Research Fellows

This year, the Broad Clinical Research Fellowships are enabling physician-investigators to explore stem cell-based approaches related to four very different medical conditions: breast cancer, kidney disease, deafness and short bowel syndrome. Each …

EiHS graduation (photo by Graham Clark Stecklein)

Local high school students graduate from USC’s summer stem cell program

Enthusiastic is the word to best describe the students from this year’s USC’s Early Investigator High School (EiHS) Stem Cell Research Program. Ten students graduated from the summer laboratory immersion program at …

Janos Peti-Peterdi with his mother and son in 2004 (Photo by Reka Peti-Peterdi)

USC kidney researcher Janos Peti-Peterdi wins Young Investigator Award

USC kidney researcher Janos Peti-Peterdi has been selected as the 2015 recipient of the ASN-AHA Young Investigator Award. Co-sponsored by the American Society of Nephrology (ASN) and the Council on the Kidney …

Senta Georgia and Neil Segil (Photo by Cristy Lytal/courtesy of Neil Segil)

New USC course follows human development from stem cells to sternum

What don’t we know about human development, and what can go wrong? By focusing on these two big questions, a new 2-unit fall course will provide USC undergraduates with the opportunity to …

Cerebral organoid derived from ALS patient stem cells (Image by Lisa Nguyen, Yaoming Wang and Angeliki Nikolakopoulou)

USC Stem Cell requests applications for new awards and fellowships

USC Stem Cell is requesting research proposals from principal investigators and senior postdoctoral scientists for three new awards and fellowships totaling $600,000.

From left, John Zaia, Dale Ando, David Hardy and Paula Cannon (Photo courtesy of the California Institute for Regenerative Medicine)

The road to a cure for HIV/AIDS

Something wonderful sometimes happens when scientists and the public get together to talk about research. All the jargon, all the technical language falls away, and it becomes instead a conversation between the …

Cerebral organoid derived from ALS patient stem cells (Image by Lisa Nguyen, Yaoming Wang and Angeliki Nikolakopoulou)

Eli and Edythe Broad Innovation Awards in Stem Biology and Regenerative Medicine 2016–2017

The Organ-in-a-Dish Challenge A gift from The Eli and Edythe Broad Foundation has established the Eli and Edythe Broad Innovation Awards in Stem Cell Biology and Regenerative Medicine at USC. This year, …

Dissection of the larval zebrafish skeleton shows facial cartilage (blue) and bone (red) (Image courtesy of the Crump Lab)

Request for Proposals: The Audrey E. Streedain Regenerative Medicine Initiative (RMI) Award at USC 2016–2018

A generous bequest by the Audrey E. Streedain Trust to the Department of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine of USC has established the Audrey Streedain …

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC (Photo by Chris Shinn)

Request for Proposals: Eli and Edythe Broad Fellowship Award 2016–2017

A recent gift from The Eli and Edythe Broad Foundation established the Eli and Edythe Broad Society of Fellows at USC. An annual fellowship award of $80,000 that includes one year of …

Barbara Driscoll (Photo courtesy of Children's Hospital Los Angeles)

Researchers create promising new model for lung injury repair

Researchers at Children’s Hospital Los Angeles and The Saban Research Institute of CHLA have created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the …

Children's Hospital Los Angeles logo

Stem cell transplantation for children with rare form of leukemia improves outcomes

Researchers in the Division of Hematology, Oncology and Blood & Marrow Transplantation at Children’s Hospital Los Angeles have shown greatly improved outcomes in using stem cell transplantation to treat patients with a …

Gage Crump gives USC undergraduates a stem cell primer. (Photo by Cristy Lytal)

USC undergraduates get a dose of stem cells in two new MEDS courses

Science fiction author Margaret Atwood has frequently stated that biotechnology itself is neutral. It is how people use it that is good or bad. In the new spring course MEDS 380 Stem …

Richard N. Merkin (Photo courtesy of Richard N. Merkin)

The Merkin Family Foundation establishes four assistant professorships in regenerative medicine at USC

In the past two years, USC’s Department of Stem Cell Biology and Regenerative Medicine has welcomed six new assistant professors to its ranks — and more are on the horizon. Thanks to a …

CIRM President Randy Mills addresses citizens and patient advocates at USC (Photo by Cristy Lytal)

California’s stem cell agency hosts public meetings with citizens and patients

This summer, leaders from the California Institute for Regenerative Medicine (CIRM) visited Los Angeles, San Diego and San Francisco to consult with citizens and patient advocates in each city. These are the …

From left to right, a red blood cell, a platelet and a white blood cell (Public domain image courtesy of the Electron Microscopy Facility at The National Cancer Institute at Frederick)

USC Stem Cell researchers poke around for blood genes

Even though the transplantation of blood stem cells, also known as bone marrow, has saved many lives over many decades, the genes that control the number or function of blood stem cells …

Researcher in the lab (Photo by Chris Shinn)

Request for Proposals: Broad Clinical Research Fellows 2015–2016

USC Stem Cell has up to four available positions to support clinical research fellow training. The fellows must have, or be training for, an MD or MD/PhD degree and have the capability …