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Snapshot of a neurovascular unit, consisting of neurons (pink), astrocytes (blue), resident microglia (green), a penetrating arteriole and capillaries (white) (Photo courtesy of the Zlokovic Lab)

Researchers clarify role of genetic risk factor in Alzheimer’s

Scientists at the Keck School of Medicine of USC have discovered that a protein known as PICALM regulates removal of toxic plaques from the brain, which could be a potential therapeutic target …

Tooth enamel damage (Image courtesy of the NIH)

Researchers discover key player in enamel regeneration

USC researchers are closer than ever to being able to regrow enamel, thanks in part to a recent scientific discovery published in the latest issue of the journal Biomaterials. In the article, …

USC graduate student Du Jiang (Photo by Cristy Lytal)

Tri-institutional Stem Cell Retreat brings together Broad centers from USC, UCLA and UCSF

Working alone, a scientist or university can only make so much progress in finding answers to basic questions or new treatments for diseases ranging from HIV to cancer to diabetes. That’s why …

Coronary vasculature in zebrafish (Image courtesy of Children's Hospital Los Angeles)

Tiny heart, big promise

The heart has its own dedicated blood supply, with coronary arteries that supply oxygen-rich blood to the heart and cardiac veins that remove deoxygenated blood. This system of vessels nourishes the heart, …

Stem cells (Image courtesy of Justin Ichida)

Request for proposals: Hearst Fellowship Award 2015–2016

A recent gift from the Hearst Foundations established the Hearst Fellows at USC. An annual fellowship award of $70,000 that includes one year of salary and benefits will be made to an …

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC (Photo by Chris Shinn)

Take a tour of USC’s stem cell research center

Video by Alric Devotta Director Andy McMahon leads a tour of the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC.

Justin Ichida, PhD (Photo by Cristy Lytal)

USC Stem Cell’s Justin Ichida, Sanofi and DRVision team up to fight ALS

USC Stem Cell researcher Justin Ichida has marshaled the expertise of pharmaceutical company Sanofi and start up DRVision Technologies along with $1.5 million in federal funding to find new drugs to fight …

Yang Chai (Photo courtesy of the Ostrow School of Dentistry of USC)

USC researchers move one step closer to natural tooth restorations

A rodent’s incisors never stop growing. It’s one of the reasons mice gnaw through cupboards, hamsters chomp mindlessly on metal cage bars and rats will chew through, well, just about anything. They …

Jay R. Lieberman is the new president of the American Association of Hip and Knee Surgeons (AAHKS).

Lieberman takes office as 25th president of national association

Jay R. Lieberman, a principal investigator with USC Stem Cell, is the new president of the American Association of Hip and Knee Surgeons (AAHKS). He is professor and chair of the Department …

Quorum sensing in hair population regeneration (Image courtesy of Cheng-Ming Chuong)

USC researcher plucks hair to grow hair

If there’s a cure for male pattern baldness, it might hurt a little. A team led by USC Stem Cell Principal Investigator Cheng-Ming Chuong has demonstrated that by plucking 200 hairs in …

USC scientist Janos Peti-Peterdi receives congratulations from Austrian President Heinz Fischer.

Peti-Peterdi is inducted into prestigious honor societies

Pioneering Keck Medicine of USC scientist Janos Peti-Peterdi, MD, PhD, received congratulations in early March in Salzburg, Austria, from Austrian President Heinz Fischer upon his induction into the European Academy of Sciences …

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC (Photo by Chris Shinn)

The Doerr Stem Cell Challenge Grants 2015–2016

To stimulate interdisciplinary stem cell research across USC Overview USC Stem Cell invites applications for the Doerr Stem Cell Challenge Grants. The goal of the program is to stimulate new interdisciplinary stem …

Yang Chai (Photo courtesy of the Ostrow School of Dentistry of USC)

Discovery could lead to biological treatment for common birth defect

Throughout every human and animal’s body, stem cell populations are responsible for the growth, regeneration and repair of tissues. While the power of some types of stem cells is already being used …

Transgenic mouse model used to target lung mesenchymal cells (green) (Image courtesy of Children's Hospital Los Angeles)

Promising new target may treat pulmonary fibrosis

By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA), along with colleagues in Mexico and Canada, …

Amy S. Lee (Photo courtesy of USC)

Faculty Spotlight: Amy S. Lee

Amy S. Lee’s major research focus is in the area of endoplasmic reticulum (ER) stress and, in particular, the ER chaperone proteins GRP78 and GRP94. Lee was the first to clone human …

Clockwise from upper left: Hao Yuan Kueh, Florian Merkle, Robert A.J. Signer, members of the audience, Pedro Batista and Joseph T. Rodgers (Photos by Cristy Lytal)

USC mini-symposium showcases the next generation of top stem cell scientists

Obesity, narcolepsy, leukemia and muscle injuries have at least one thing in common: they are engaging the next generation of top stem cell scientists. Five of these scientists presented their research at …

David Hinton

Faculty Spotlight: David R. Hinton

David Hinton’s research is focused on developing novel therapies for age-related macular degeneration (AMD) – the leading cause of irreversible blindness in the elderly. He is approaching this goal in two main …

Illustration of the HIV virus

CIRM-funded clinical trial aimed at blocking HIV/AIDS in people gets the go ahead

An innovative therapy using a patient’s own stem cells, modified to resist infection with the AIDS virus, has been given approval by the Food and Drug Administration (FDA) to begin a clinical …

USC PhD student Louise Menendez examines the prototype of a potential device to treat patients with liver disease. (Photo by Cristy Lytal)

“Million-dollar ideas” seminar

At a special seminar on February 24, USC Stem Cell Principal Investigators discussed their “million-dollar ideas” for creating new tools and technologies to usher in the era of regenerative medicine. They shared …

From right, biotech professionals Andy McMahon, Steve Kay, Stephen Gruber, Ray Stevens and David Meyer (Photo by Gus Ruelas)

USC summit marks rebirth of biotech era in Los Angeles

Los Angeles city and county policymakers and educational institutions laid the groundwork for the region’s biotechnology strategy at a summit on the USC Health Sciences Campus. The Los Angeles Biotech Summit drew …