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A lab-grown kidney organoid made of human collecting duct cells shows elongated tubules—the segment of the kidney primarily affected by the incurable genetic condition called autosomal recessive polycystic kidney disease (ARPKD). (Image by Carrie Zhang/Li Lab/USC Stem Cell); featured image for PKD Foundation provides support for kidney disease research by USC Stem Cell’s Zhongwei Li

PKD Foundation provides support for kidney disease research by USC Stem Cell’s Zhongwei Li

A two-year, $240,000 grant will back studies developing lab-made tissue to drive progress fighting an incurable genetic condition, autosomal recessive polycystic kidney disease. The PKD Foundation has awarded a two-year grant totaling …

Medical implant illustration; featured image for What If the device changing brain medicine was free for anyone to build?

What If the device changing brain medicine was free for anyone to build?

A USC Viterbi bioengineer’s implantable device that any researcher can use, modify, and build on is nearly ready for its first animal test. Getting here required reinventing not just the hardware, but …

Illustration of brain projection; featured image for There is no “brain x-ray.” A USC neurosurgeon-engineer is helping build better ones

There is no “brain x-ray.” A USC neurosurgeon-engineer is helping build better ones

A USC neurosurgeon and engineer argues that the tools to monitor the brain cheaply and without surgery are within reach — and that getting there requires putting engineers where patients actually are. …

Illustration of medical devices; featured image for Four innovators gather at USC to explore the devices changing medicine

Four innovators gather at USC to explore the devices changing medicine

Clinical translation was the stated theme of the biomedical devices and imaging session at the Alfred E. Mann Department of Biomedical Engineering‘s 50th anniversary symposium Sept. 3. The department, jointly part of …

Teeth with lesions; featured image for Think enamel erosion is irreversible? Think again.

Think enamel erosion is irreversible? Think again.

After decades of research, Ostrow faculty member Janet Moradian-Oldak prepares to bring a short peptide that can generate a biomimetic version of tooth enamel to market. FOR DECADES, PROFESSOR JANET MORADIAN-OLDAK has …

Lit-up tumor (Image/Midjourney); featured image for A new way to help CAR-T cells fight solid tumors could change cancer treatment

A new way to help CAR-T cells fight solid tumors could change cancer treatment

USC researchers developed a technique that uses focused ultrasound to temporarily “light up” solid tumors, giving cancer-fighting immune cells a target they can finally recognize. For more than a decade, CAR-T cell …

Chuck Murry in the lab; featured image for Heart health enters the future with a $28.7 million gift from the Marcus Foundation

Heart health enters the future with a $28.7 million gift from the Marcus Foundation

In a landmark moment for both the treatment of heart disease and philanthropic support, The Marcus Foundation has awarded the head of USC Stem Cell, Chuck Murry, MD, PhD, $28.7 million to …

Thymus; featured image for Thymus-derived hormone may help suppress age-related inflammation

Thymus-derived hormone may help suppress age-related inflammation

In animal models, researchers from the Keck School of Medicine of USC found that targeting the thymus can reduce age-related inflammation and improve cancer outcomes. Chronic, low-grade inflammation in the body—a phenomenon …

A breast cancer cell. (Image courtesy of the National Cancer Institute, National Institutes of Health); featured image for Finding a tumor’s soft spot to power-up immunotherapy

Finding a tumor’s soft spot to power-up immunotherapy

USC researchers have developed a new “black box” tool to measure the softness of tumor cells, an insight that could be crucial for more effective cancer treatment. Researchers at the USC Viterbi …

Lab-grown kidney organoid (Image courtesy of the Lindström Lab); featured image for USC Stem Cell scientists engineer “synthetic organizer” cells to improve kidney organoids

USC Stem Cell scientists engineer “synthetic organizer” cells to improve kidney organoids

Mapping the human kidney, researchers discovered an unrecognized developmental axis and engineered “synthetic organizer” cells to recreate key developmental signals, producing improved, reproducible lab-grown organoids for studying disease and therapies. In a …

From left, John Oghalai and Brian Applegate with the cochleoscope (Photo by Cristy Lytal); featured image for USC startup receives up to $3.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop an inner ear imaging device

USC startup receives up to $3.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop an inner ear imaging device

AO Technologies, founded by USC researchers John Oghalai and Brian Applegate, has secured an ARPA-H small business award to develop a cochleoscope for clinical imaging of the inner ear. USC researchers John …

Engineered immune cells (red) attacking breast cancer cells (blue). The red cells are genetically engineered macrophages designed to selectively recognize, engulf and destroy breast cancer cells (blue), demonstrating a promising new cell-based immunotherapy approach. (Image by Shi Yue/Ying Lab); featured image for USC Stem Cell-led team creates a renewable cell source for cancer immunotherapy and beyond

USC Stem Cell-led team creates a renewable cell source for cancer immunotherapy and beyond

Researchers develop a way to grow and genetically engineer the progenitor cells that give rise to macrophages, a type of first-responder immune cell that shows promise for developing immunotherapies for cancers and …

At the lab bench (Photo by Chris Shinn); featured image for 2026 Call for Applications: NIH T32 PhD Fellowships in Developmental Biology, Stem Cells, and Regeneration

2026 Call for Applications: NIH T32 PhD Fellowships in Developmental Biology, Stem Cells, and Regeneration

All PhD students who are conducting research related to developmental biology, stem cell biology, and/or regenerative medicine are encouraged to apply for a training fellowship. We have two slots available for a …

Kidney model (Image by Midjourney); featured image for Tiny particles in urine could be the key to treating a deadly childhood kidney disease

Tiny particles in urine could be the key to treating a deadly childhood kidney disease

USC Viterbi researchers have discovered that a naturally occurring nanoparticle found in urine shows early promise as a treatment, and potentially a prenatal intervention, for a rare disease that kills newborns and …

Man pressing his hand against a painful jaw; featured image for USC researchers study impacts of synovial lymphatic system on TMJ

USC researchers study impacts of synovial lymphatic system on TMJ

A recent Nature Communications article sheds light on how fluid drainage systems may worsen jaw pain in the 5 to 8 percent of Americans affected by temporomandibular joint disorders. Problems with jaw …

A PhD student in the lab (Photo by William Vasta); featured image for 2026 USC Stem Cell/SPARK at USC Innovation Catalyst Grant in Regenerative Medicine

2026 USC Stem Cell/SPARK at USC Innovation Catalyst Grant in Regenerative Medicine

About this call The USC Stem Cell/SPARK at USC grant is focused on the support of regenerative medicine innovation (therapeutics or diagnostics). Integration of AI technology is highly encouraged. The new SPARK …

2026 USC CIRM COMPASS graduates (Photo by Amor Mathershed); featured image for Undergraduate stem cell research takes the spotlight at USC CIRM COMPASS symposium

Undergraduate stem cell research takes the spotlight at USC CIRM COMPASS symposium

USC Stem Cell prepares undergraduates to present research and become the regenerative medicine workforce of the future. Stem cell research took center stage at the year-end symposium for the USC CIRM COMPASS …

Lab grown human synthetic kidney organoids (hSKOs), also known as human kidney progenitor assembloids (hKPAs), showing the formation of radial nephrons connected to a central collecting system. (Image by Pedro Medina/Li Lab/USC Stem Cell); featured image for USC researchers launch study of the most complex lab-grown kidney structures

USC researchers launch study of the most complex lab-grown kidney structures

A $2.1 million grant from CIRM supports the new project designed to understand how mature lab-grown kidney structures, which combine the kidney’s filtering and urine-collecting components, can improve the study of disease …

Heliya Ziaei (Photo courtesy of the Ostrow School of Dentistry of USC); featured image for Driven to impact

Driven to impact

Powered by her Ostrow experience, Heliya Ziaei is well positioned to blend research and patient care as a clinician-scientist. Though Heliya Ziaei, PhD ’26, arrived at the Herman Ostrow School of Dentistry …

Tiffany Wang; featured image for USC CIRM COMPASS Scholar Tiffany Wang finds belonging, embraces research and leadership

USC CIRM COMPASS Scholar Tiffany Wang finds belonging, embraces research and leadership

A first-generation college student, Tiffany Wang treasures the support and opportunities for growth she found at the USC Leonard Davis School of Gerontology. Tiffany Wang, member of the USC Leonard Davis School …