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A cell showing the enzyme BirA*G3, which tags the proteins of the "secretome" (Image courtesy of the McMahon Lab)

This mouse can’t keep a secret about the “secretome”

The “secretome” refers to proteins that are secreted by a cell, a tissue or an organism. In a new study published in Open Biology, USC Stem Cell scientist Andy McMahon and his …

From left, Albert Almada and Miller Huang

The Baxter Foundation celebrates promising research in muscle loss and pediatric cancer

For more than 60 years, the Donald E. and Delia B. Baxter Foundation has supported innovative biomedical research at the Keck School of Medicine of USC, each year granting $100,000 awards to …

Neil Segil (Photo by Chris Shinn)

In Memoriam: Neil Segil, PhD (1953–2022)

Professor, Department of Stem Cell Biology and Regenerative Medicine, and USC Caruso Department of Otolaryngology–Head and Neck Surgery, Keck School of Medicine of USC It is with sadness that we share that …

David Hinton

In Memoriam: David R. Hinton, MD, FARVO

Professor of Pathology; Gavin S. Herbert Professorship in Vision Research; Associate Dean for Vision Science; Vice Chair of Pathology; Director, Keck School of Medicine of USC/CalTech MD/PhD Program; Director, Dean’s Research Scholars …

Haoze (Vincent) Yu and Litao Tao (Photo courtesy of Haoze (Vincent) Yu)

USC Stem Cell alumni Litao Tao and Haoze (Vincent) Yu bring their A game to new positions in academia and industry

Scientists Litao Tao and Haoze (Vincent) Yu were colleagues and team players for many years both inside and outside of Neil Segil’s lab at the Eli and Edythe Broad CIRM Center for …

The USC Mentoring Awards honor faculty who contribute to an engaging, supportive and inclusive academic environment through their mentorship of students and faculty. (Photo courtesy of Shutterstock)

Neil Segil is among members of Health Sciences Campus honored with USC Mentoring Awards

Several faculty members from the USC Health Sciences Campus received 2022 USC Mentoring Awards on April 14 at a reception organized by the USC Center for Excellence in Teaching. These awards recognize …

Altered cells create an electrical “fire” in patients with epilepsy. (BioRender illustration by Aswathy Ammothumkandy/Bonaguidi Lab/USC Stem Cell)

Newborn cells in the epileptic brain provide a potential target for treatment

Over the years, everyone loses a few brain cells. A study led by scientists from USC Stem Cell and the USC Neurorestoration Center presents evidence that adults can replenish at least some …

Detail of brain from Mukund Iyer's first place winning entry (Image by Mukund Iyer)

Communicating science visually: Mukund Iyer, MaryAnne Achieng and Stephanie Chang win the 2022 Winter BioRender contest

For his graphic on immune cell function in the brain, Mukund Iyer took first place in the Winter 2021 BioRender Illustration competition for his schematic of breast cancer cells’ entry through the …

New subretinal implant A new subretinal implant invented by Mark Humayun has been shown to improve vision in some patients who suffered from dry age-related macular degeneration.

USC discovery shows long-term viability of stem cell derived retinal implant

Doctors and biomedical engineers who implant cells and tissues into patients to restore motion or eyesight have long been challenged by potential rejection of the implant by the patient’s own immune system. …

Mark Humayun (Photo by Gus Ruelas)

Mark Humayun among USC faculty named 2021 AAAS Fellows

The American Association for the Advancement of Science (AAAS) has elected three USC professors to become AAAS fellows in 2021. The council designates members with this distinction whose “efforts on behalf of …

Confocal microscopy image of an adult zebrafish head with neural crest-derived cells in red. The Crump lab has used single-cell sequencing to understand how these cells build and repair the head skeleton, with implications for understanding human craniofacial birth defects and improving repair of skeletal tissues. (Image by Hung-Jhen Chen/Crump Lab)

A crowning achievement in understanding head development

Cranial neural crest cells, or CNCCs, contribute to many more body parts than their humble name suggests. These remarkable stem cells not only form most of the skull and facial skeleton in …

Yichen Li

Curiosity, commitment and compassion drive Yichen Li’s research in neurodegenerative diseases

Yichen Li has always been driven to understand the world around her. Growing up in an Eastern province in China, Li’s inquisitive nature steered her toward science. “When I was a girl, …

Image courtesy of the Ostrow School of Dentistry of USC

USC collaboration helps FaceBase reach 1,000-dataset milestone

The data repository allows craniofacial scientists to share data, which could ultimately lead to improved care for patients with craniofacial developmental disorders. Rapid technological development in the past decade has allowed scientists …

Aswathy Ammothumkandy and her family

USC Stem Cell postdoc Aswathy Ammothumkandy recognized by the American Epilepsy Society

USC Stem Cell postdoctoral trainee Aswathy Ammothumkandy vividly recalls when the tour guide shared the story of Dolly the cloned sheep during her ninth-grade field trip to the regional science center in …

Ear exam

Study reveals common loud noises cause fluid buildup in the inner ear and suggests simple possible cure for noise-induced hearing loss

Exposure to loud noise, such as a firecracker or an ear-splitting concert, is the most common preventable cause of hearing loss. Research suggests that 12% or more of the world population is …

Smog

How does air pollution influence Alzheimer’s risk?

Higher exposure to air pollution is strongly associated with cognitive impairment and Alzheimer’s disease, especially for people with certain genetic risk factors for the disease. Exactly how pollution interacts with these genes …

Impromptu McMahon lab meeting

USC Stem Cell: An incubator for medicine of the 21st century

Just over a decade ago, USC was a university with a few scattered stem cell biologists, and a vision for total transformation. The university was committed to designing a unique “incubator” for …

Illustration by Jonathan Haase

Cycles of a fasting-mimicking diet help mice live longer, healthier

While many diets have been studied for effectiveness in preventing obesity and heart disease in both mice and humans, research on the effects and benefits of short, periodic cycles of fasting on obesity and heart health are lacking. In a new USC study on the health effects of a low-calorie diet that mimics …

mourning gecko

Aided by stem cells, a lizard regenerates a perfect tail for the first time in 250 million years

Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology)

Bérénice Benayoun receives prestigious investigator-focused grant

The Maximizing Investigators’ Research Award directly supports scientists, providing stability, flexibility and more opportunities for breakthroughs. The National Institute of General Medical Sciences has awarded an R35 Maximizing Investigators’ Research Award (MIRA) …