David Cobrinik

What makes a cell turn cancerous?

Story courtesy of Children’s Hospital Los Angeles Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age and accounts for approximately 4% of childhood cancers. If …

Developing retina (Image by Cobrinik Lab)

CHLA team identifies developmental stage for eye tumor in children

Investigators at Children’s Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The …


Stem cell-derived retinal organoid imaging offers real-time insights into the developmental origins of blinding eye diseases

A multidisciplinary team of researchers from the University of Southern California (USC) Roski Eye Institute, Children’s Hospital Los Angeles (CHLA) and the USC Viterbi School of Engineering used stem cell-derived retinal organoids …

Fred H. Gage delivered a brainy keynote address. (Photo by Cristy Lytal)

USC Stem Cell Symposium creates scientific synergy

Provost Michael Quick convened the inaugural USC Stem Cell Symposium with a straightforward truth about the future of regenerative medicine: “it will take a dedicated community of scholars across the disciplines to …

David Cobrinik (Photo by Cristy Lytal)

How a single genetic change causes retinal tumors in children

Retinoblastoma is a retinal tumor usually affecting children one to two years of age. Although rare, it is the most common malignant tumor of the eye in children. Left untreated, retinoblastoma can …

David Cobrinik, MD, PhD