Broken eggs

USC researchers regenerate skull tissue using stem cells and 3-D printed scaffolding in swine

Every year, surgeons perform more than 5,000 cranioplasties—surgeries that restore cranial defects—on patients who have experienced critical size cranial defects resulting from congenital defects, head trauma or tumor removals. Traditional materials used …

Conventional treatment for craniosynostosis often involves surgery and cranial helmets during the long recovery process. (Photo courtesy of iStock)

Stem cells may correct deformity and restore brain function after childhood disorder

USC scientists have regenerated parts of the skull affected by a common birth defect called craniosynostosis. Using stem cells to regenerate parts of the skull, USC scientists partially corrected a skull deformity …

Yang Chai (Photo courtesy of the Ostrow School of Dentistry of USC)

Research group awarded $12 million to establish tissue regeneration center

A research team called C-DOCTOR (Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration), initiated by the Ostrow School of Dentistry of USC, is one step closer to developing products that …

Yang Chai (Photo courtesy of the Ostrow School of Dentistry of USC)

Discovery could lead to biological treatment for common birth defect

Throughout every human and animal’s body, stem cell populations are responsible for the growth, regeneration and repair of tissues. While the power of some types of stem cells is already being used …

Human skull with sutures (Public domain image courtesy of Gray's Anatomy)

USC, UCLA and UCSF put their heads together to find stem cell-based cures for craniofacial defects

One in every 2,000 babies is born with a skull that can’t grow normally. Various sections of these babies’ skulls are fused together at joints called sutures, constricting the developing brain and …

Mark Urata, MD, DDS