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(Image courtesy of iStock); featured image for USC team develops a powerful new analytical tool to advance CAR T cell therapy research

USC team develops a powerful new analytical tool to advance CAR T cell therapy research

The comprehensive analytical platform uses laser technology to analyze CAR T cells and has already revealed ways to optimize their manufacturing, including how to identify when CAR T cells are likely to …

A time-lapse shows the Wang Lab’s EchoBack CAR T-cells attacking a large tumor mass. The green labeled points are the tumor cells. (Image by Longwei Liu/Wang Lab); featured image for New “smart” immune cells: A breakthrough for long-lasting tumor destruction

New “smart” immune cells: A breakthrough for long-lasting tumor destruction

USC Viterbi researchers have engineered a new immune cell that when activated by ultrasound can continuously sense and destroy cancer cells for extended periods. Imagine a super-charged immune cell that can launch …

Yali Dou, PhD, Marion and Harry Keiper Chair in Cancer Research at the Keck School of Medicine of USC, and associate director for basic research at USC Norris Comprehensive Cancer Center, has been elected an AAAS 2025 fellow. (Photo by Steve Cohn); featured image for AAAS elects Keck School of Medicine of USC molecular biologist Yali Dou as 2025 fellow

AAAS elects Keck School of Medicine of USC molecular biologist Yali Dou as 2025 fellow

Dou has broken new ground in the basic understanding of an enzyme that can cause leukemia and other cancers, and harnessed that knowledge at USC to develop potential therapies. Molecular biologist Yali …

Preet M. Chaudhary, MD, PhD, a professor of medicine, the Bloom Family Chair in Lymphoma Research, chief of the Nohl Division of Hematology (Photo courtesy of USC); featured image for Two USC innovators—Preet Chaudhary and Michael Selsted—honored by the National Academy of Inventors

Two USC innovators—Preet Chaudhary and Michael Selsted—honored by the National Academy of Inventors

Harnessing the body’s natural defenses, these researchers are advancing the future of immune-based treatments to develop breakthroughs in treating diseases ranging from rheumatoid arthritis and sepsis to cancer. Two researchers from the …

Illustration of man lifting weights by a refrigerator (Illustrations by Drue Wagner); featured image for Turn back the clock on aging

Turn back the clock on aging

There’s no way to stop the march of time, but innovative research by USC scholars points the way to a longer, healthier and more vibrant life. About 10 years ago, when George …

USC biomedical engineers have harnessed focused ultrasound to improve CRISPR, a revolutionary tool that enables the DNA in living organisms to be modified. (Image byWang Lab and Pepper Workshop); featured image for New CRISPR toolkit to allow remote-controlled genome editing

New CRISPR toolkit to allow remote-controlled genome editing

USC Viterbi biomedical engineers harness focused ultrasound to revolutionize CRISPR’s capabilities to treat countless diseases. Thanks to CRISPR, our medical specialists will soon have unprecedented control over how they treat and prevent …

Adaptive immune cells, such as B cells (pictured), are a key component of a youthful immune system. (Image courtesy of the National Institutes of Allergy and Infectious Diseases); featured image for USC Stem Cell mouse study sheds light on the secret to maintaining a youthful immune system

USC Stem Cell mouse study sheds light on the secret to maintaining a youthful immune system

What keeps some immune systems youthful and effective in warding off age-related diseases? In a new paper published in Cellular & Molecular Immunology, USC Stem Cell scientist Rong Lu and her collaborators …

; featured image for USC’s Rong Lu and Caltech’s Michael B. Elowitz win the NIH Director’s Transformative Research Award for their new approach to study blood and immune cell production in bone marrow

USC’s Rong Lu and Caltech’s Michael B. Elowitz win the NIH Director’s Transformative Research Award for their new approach to study blood and immune cell production in bone marrow

Is it possible to study the production of blood and immune cells inside the bone marrow? For the first time ever, the answer is yes, thanks to a new approach pioneered by …

Photo/iStock; featured image for An early blood test can predict survival in patients with metastatic prostate cancer, shows USC study

An early blood test can predict survival in patients with metastatic prostate cancer, shows USC study

The non-invasive test, which measures circulating tumor cells in the blood, can predict treatment response, disease progression and overall survival in men newly diagnosed with metastatic prostate cancer, according to new research …

Charles (Chuck) Murry (Photo by Gavin Sisk/ University of Washington); featured image for USC Stem Cell welcomes new leader, renowned physician-scientist Chuck Murry

USC Stem Cell welcomes new leader, renowned physician-scientist Chuck Murry

Charles (Chuck) Murry, MD, PhD, has been appointed as the next head of USC Stem Cell. In that capacity, he will be the chair of the Department of Stem Cell Biology and …

New pilot grants will forge collaborations between researchers at Keck School of Medicine of USC and the Alfred E. Mann Department of Biomedical Engineering. (Image courtesy of the USC Viterbi School of Engineering); featured image for Forging research partnerships for future medical breakthroughs

Forging research partnerships for future medical breakthroughs

New Mann Engineering in Medicine Pilot Grants program will build ongoing research collaborations between USC Viterbi School of Engineering and Keck School of Medicine of USC. The lifesaving medical discoveries and therapeutics …

Dwight C. and Hildagarde E. Baum Chair in Biomedical Engineering Peter Yingxiao Wang. Image/David Baillot, UC San Diego Jacobs School of Engineering.; featured image for Turning a tumor’s “shield” into a weapon against itself

Turning a tumor’s “shield” into a weapon against itself

USC Viterbi biomedical engineers have designed a new protein that targets and disables tumor cells’ defenses while marking cancer cells for death. Tumor cells are “cunning,” according to Peter Yingxiao Wang. They …

Clockwise from top left – Yang Chai, Denis Evseenko, Peter Kuhn and Justin Ichida, NAI 2024 class of senior members. (Chai photo/ Chris Shinn; Evseenko and Ichida photos/Richard Carrasco; Kuhn photo/Peter Zhaoyu Zhou); featured image for National Academy of Inventors elects four Keck School of Medicine of USC faculty as senior members

National Academy of Inventors elects four Keck School of Medicine of USC faculty as senior members

The National Academy of Inventors (NAI), a nonprofit member organization that encourages inventors in higher education, has announced that four researchers from the Keck School of Medicine of USC are part of …

Eun Ji Chung; featured image for Nanoparticles “hitchhike” on immune cells to catch cancer metastasis early

Nanoparticles “hitchhike” on immune cells to catch cancer metastasis early

USC Viterbi researchers have designed particles that can light up the lymph node cancer cells otherwise undetectable by MRI. Our lymph nodes are the canaries in the coal mine of our immune …

Rong Lu (right) and Du Jiang (Photo by Gal Manella); featured image for USC Stem Cell study shows how gene activity modulates the amount of immune cell production in mice

USC Stem Cell study shows how gene activity modulates the amount of immune cell production in mice

As people age or become ill, their immune systems can become exhausted and less capable of fighting off viruses such as the flu or COVID-19. In a new mouse study funded in …

Oliver Bell and Daniel Bsteh; featured image for USC Stem Cell study throws our understanding of gene regulation for a loop

USC Stem Cell study throws our understanding of gene regulation for a loop

The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be …

(Image courtesy of the USC Davis School of Gerontology); featured image for Eat well, age well

Eat well, age well

Diet interacts with genetics and impacts the way we age. Here’s what USC researchers are finding out about nutrition and healthy aging. The old adage “You are what you eat” may be …

Building an Incubator for Medicine of the 21st Century; featured image for Building an Incubator for Medicine of the 21st Century

Building an Incubator for Medicine of the 21st Century

USC Stem Cell is pleased to introduce our new publication. We hope you’ll enjoy reflecting back on our history, while looking ahead to the transformative times to come. Read now at https://stemcell.keck.usc.edu/wp-content/themes/stemcell/incubator.

PROFESSOR LONGWEI LIU (PHOTO COURTESY OF SHANSHAN QIN); featured image for Illuminating cancer

Illuminating cancer

Longwei Liu joins USC Viterbi and the Wang Lab to uncover the secret interactions between immune cells and cancer cells with the help of fluorescent trackers.   Through the lens of a …

(Image courtesy of iStock); featured image for $2 million grant boosts technological advancements in cutting-edge cell therapy manufacturing facility

$2 million grant boosts technological advancements in cutting-edge cell therapy manufacturing facility

The Keck School of Medicine of USC has received $2 million from the California Institute of Regenerative Medicine (CIRM) to further augment its newly launched cGMP Laboratory, a state-of-the-art facility designed to …