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Motor neurons derived from an ALS patient (Image courtesy of the Ichida Lab); featured image for USC announces winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards

USC announces winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards

Two collaborative teams within USC Stem Cell are developing new approaches that could eventually help patients with heart disease, frontotemporal dementia and amyotrophic lateral sclerosis (ALS). The teams are the winners of …

Mark Humayun (Photo by Gus Ruelas); featured image for USC’s Mark Humayun to receive National Medal of Technology and Innovation

USC’s Mark Humayun to receive National Medal of Technology and Innovation

President Barack Obama will bestow the National Medal of Technology and Innovation to USC University Professor Mark Humayun at a ceremony in Washington, DC, on January 22. Humayun, who holds joint appointments …

The gene Prkci promotes the generation of differentiated cells (red). However if Prkci activity is reduced or absent, neural stem cells (green) are promoted. (Image by In Kyoung Mah); featured image for A Prkci gene keeps stem cells in check

A Prkci gene keeps stem cells in check

When it comes to stem cells, too much of a good thing isn’t wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance …

From right, Qi-Long Ying, director of the Chang Stem Cell Engineering Facility; Daniel Chang; Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC; and Cai Li Chang (Photo by Cristy Lytal); featured image for Chang Stem Cell Engineering Facility brings gene editing to USC and beyond

Chang Stem Cell Engineering Facility brings gene editing to USC and beyond

Once the stuff of science fiction, genetic engineering is now offered on a fee-for-service basis at USC. On September 19, USC Stem Cell faculty and staff welcomed their supporters, the Chang and …

Motor neurons derived from an ALS patient (Image courtesy of the Ichida Lab); featured image for USC Stem Cell researcher Justin Ichida receives $300,000 Muscular Dystrophy Association grant

USC Stem Cell researcher Justin Ichida receives $300,000 Muscular Dystrophy Association grant

Ten percent of all patients with two neurodegenerative diseases — frontotemperal dementia (FTD) and amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease — possess a mutation in the same gene. …

Age-related macular degeneration; featured image for Americans for Cures animates stem cell research at USC and UCSD

Americans for Cures animates stem cell research at USC and UCSD

Americans for Cures produced a white board animation showcasing a clinical trial for age-related macular degeneration, led by USC Stem Cell researchers David Hinton and Mark Humayun:

Clockwise from top left: Andre Luis de Castro Abreu, Victoria Forte, Kathy Schall and Rodrigo Martínez Monedero (Photos by Cristy Lytal); featured image for USC Stem Cell selects inaugural Broad Clinical Research Fellows

USC Stem Cell selects inaugural Broad Clinical Research Fellows

This year, the Broad Clinical Research Fellowships are enabling physician-investigators to explore stem cell-based approaches related to four very different medical conditions: breast cancer, kidney disease, deafness and short bowel syndrome. Each …

From left, Wolfgang Fink and Michael Bonaguidi (Photo by Cristy Lytal); featured image for USC Stem Cell researcher Michael Bonaguidi dissects the film Self/Less

USC Stem Cell researcher Michael Bonaguidi dissects the film Self/Less

Can science make us immortal? At a recent Los Angeles screening of director Tarsem Singh’s science fiction thriller Self/Less, USC Stem Cell researcher Michael Bonaguidi and University of Arizona researcher Wolfgang Fink …

Fresh veggies, anyone? (Photo by Bob Nichols); featured image for Diet that mimics fasting appears to slow aging

Diet that mimics fasting appears to slow aging

Want to lose abdominal fat, get smarter and live longer? New research led by USC Stem Cell principal investigator Valter Longo shows that periodically adopting a diet that mimics the effects of …

Michael Quick’s appointment fits his personal background and the ideal of USC. (Photo/Steve Cohn); featured image for Michael Quick to serve on state stem cell oversight panel

Michael Quick to serve on state stem cell oversight panel

Sought: A neuroscientist with leadership experience to serve on the committee that reviews California’s funding of stem cell research. Found: Neurobiologist Michael Quick, provost and senior vice president for academic affairs at …

From left, Jon-Paul Pepper, Min Yu and Kevin S. King; featured image for The Baxter Foundation awards grants to USC researchers Min Yu, Jon-Paul Pepper and Kevin S. King

The Baxter Foundation awards grants to USC researchers Min Yu, Jon-Paul Pepper and Kevin S. King

It takes a very special doctor to push beyond existing patient treatments and engage in the quest for new ones. That’s why the Donald E. and Delia B. Baxter Foundation has selected …

Snapshot of a neurovascular unit, consisting of neurons (pink), astrocytes (blue), resident microglia (green), a penetrating arteriole and capillaries (white) (Photo courtesy of the Zlokovic Lab); featured image for Researchers clarify role of genetic risk factor in Alzheimer’s

Researchers clarify role of genetic risk factor in Alzheimer’s

Scientists at the Keck School of Medicine of USC have discovered that a protein known as PICALM regulates removal of toxic plaques from the brain, which could be a potential therapeutic target …

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC (Photo by Chris Shinn); featured image for Take a tour of USC’s stem cell research center

Take a tour of USC’s stem cell research center

Video by Alric Devotta Director Andy McMahon leads a tour of the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC.

Justin Ichida, PhD (Photo by Cristy Lytal); featured image for USC Stem Cell’s Justin Ichida, Sanofi and DRVision team up to fight ALS

USC Stem Cell’s Justin Ichida, Sanofi and DRVision team up to fight ALS

USC Stem Cell researcher Justin Ichida has marshaled the expertise of pharmaceutical company Sanofi and start up DRVision Technologies along with $1.5 million in federal funding to find new drugs to fight …

Clockwise from upper left: Hao Yuan Kueh, Florian Merkle, Robert A.J. Signer, members of the audience, Pedro Batista and Joseph T. Rodgers (Photos by Cristy Lytal); featured image for USC mini-symposium showcases the next generation of top stem cell scientists

USC mini-symposium showcases the next generation of top stem cell scientists

Obesity, narcolepsy, leukemia and muscle injuries have at least one thing in common: they are engaging the next generation of top stem cell scientists. Five of these scientists presented their research at …

David Hinton; featured image for Faculty Spotlight: David R. Hinton

Faculty Spotlight: David R. Hinton

David Hinton’s research is focused on developing novel therapies for age-related macular degeneration (AMD) – the leading cause of irreversible blindness in the elderly. He is approaching this goal in two main …

USC PhD student Louise Menendez examines the prototype of a potential device to treat patients with liver disease. (Photo by Cristy Lytal); featured image for “Million-dollar ideas” seminar

“Million-dollar ideas” seminar

At a special seminar on February 24, USC Stem Cell Principal Investigators discussed their “million-dollar ideas” for creating new tools and technologies to usher in the era of regenerative medicine. They shared …

From left, Toshio Miki, Qi-Long Ying, Paula Cannon (Photos by Cristy Lytal and Don Milici); featured image for Three USC researchers win $4.3 million in awards from California’s stem cell agency

Three USC researchers win $4.3 million in awards from California’s stem cell agency

Three scientists from Keck Medicine of USC have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine (CIRM) for research that includes creating a temporary liver for patients, finding …

Michael Bonaguidi (Photo by Joseph Shin); featured image for Michael Bonaguidi contributes brain power to stem cell research at USC

Michael Bonaguidi contributes brain power to stem cell research at USC

Video by Alric Devotta As a child, Michael Bonaguidi dreamed of shaping cities as an architect or engineer. Now, he dreams of shaping brains as the newest principal investigator to join USC’s …

Neil Segil (Photo by Cristy Lytal); featured image for Neil Segil uses stem cells to seek treatments for hearing loss

Neil Segil uses stem cells to seek treatments for hearing loss

During most of his twenties, Neil Segil couldn’t really imagine pursuing a career in science and being a professor. Now he’s doing both — as a principal investigator with USC Stem Cell …