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Paula Cannon, PhD, at the American Society of Gene and Cell Therapy 27th Annual Meeting in Baltimore.; featured image for USC scientist Paula Cannon takes the reins as president of the American Society of Gene and Cell Therapy

USC scientist Paula Cannon takes the reins as president of the American Society of Gene and Cell Therapy

Paula Cannon, a Distinguished Professor at the Keck School of Medicine of USC, heads the world’s largest organization devoted to developing next-generation therapies that address the underlying causes of disease. USC geneticist …

Lab grown human nephron progenitor cells (Image by Biao Huang/Li Lab); featured image for USC-led study introduces a new and improved way to grow the cells that give rise to the kidney’s filtration system

USC-led study introduces a new and improved way to grow the cells that give rise to the kidney’s filtration system

In a new study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney’s filtration system, the nephrons. NPCs …

Dwight C. and Hildagarde E. Baum Chair in Biomedical Engineering Peter Yingxiao Wang. Image/David Baillot, UC San Diego Jacobs School of Engineering.; featured image for Turning a tumor’s “shield” into a weapon against itself

Turning a tumor’s “shield” into a weapon against itself

USC Viterbi biomedical engineers have designed a new protein that targets and disables tumor cells’ defenses while marking cancer cells for death. Tumor cells are “cunning,” according to Peter Yingxiao Wang. They …

Lines of green fluorescent protein (GFP) show cells lighting up red and turning into muscle cells on the GFP scaffold. (Image by Mher Garibyan); featured image for A green light to build muscle cells on command

A green light to build muscle cells on command

It may sound like something from science fiction. To grow and modify muscle tissue in the lab using technology that shapes the muscle cells, blood vessels and nerves into whatever pattern you …

Building an Incubator for Medicine of the 21st Century; featured image for Building an Incubator for Medicine of the 21st Century

Building an Incubator for Medicine of the 21st Century

USC Stem Cell is pleased to introduce our new publication. We hope you’ll enjoy reflecting back on our history, while looking ahead to the transformative times to come. Read now at https://stemcell.keck.usc.edu/wp-content/themes/stemcell/incubator.

(Image courtesy of iStock); featured image for $2 million grant boosts technological advancements in cutting-edge cell therapy manufacturing facility

$2 million grant boosts technological advancements in cutting-edge cell therapy manufacturing facility

The Keck School of Medicine of USC has received $2 million from the California Institute of Regenerative Medicine (CIRM) to further augment its newly launched cGMP Laboratory, a state-of-the-art facility designed to …

Senta Georgia; featured image for Senta Georgia reflects on Title IX and becoming the first Black PhD scientist to earn tenure at the Keck School of Medicine of USC

Senta Georgia reflects on Title IX and becoming the first Black PhD scientist to earn tenure at the Keck School of Medicine of USC

When USC Stem Cell researcher Senta Georgia was granted tenure on March 10, 2023, she became the first Black PhD scientist to earn this promotion in the history of the Keck School …

From left, study authors Jiya Eerdeng, Ivon Garcia, Rong Lu, Charles Bramlett, Mary Vergel-Rodriguez, and Yeachan Lee (Photo by Bowen Wang); featured image for Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study at USC

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study at USC

Why do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop the blood cancer? In a new study published in Blood, scientists from …

The new lab’s collaborative structure promises to play a key role in the development of groundbreaking advancements in health care. (Photo/Steve Cohn); featured image for New USC/CHLA cGMP Lab opens to accelerate next-generation cell therapy

New USC/CHLA cGMP Lab opens to accelerate next-generation cell therapy

A new laboratory designed to advance early-stage research into lifesaving, commercially viable therapies was celebrated on the USC Health Sciences Campus Tuesday night. Housed at the USC Norris Comprehensive Cancer Center, the …

cancerous cell; Image courtesy of the Ostrow School of Dentistry of USC; featured image for Mini organs pave the way for understanding gastroesophageal cancer

Mini organs pave the way for understanding gastroesophageal cancer

USC researcher Dechen Lin has created miniature organs — with the hope of fighting a rare type of cancer. CANCERS THAT IMPACT THE JUNCTION of the esophagus and the stomach are rare …

nurse visits with a patient; featured image for USC and CHLA awarded $8 million to expand access to cell and gene therapy clinical trials

USC and CHLA awarded $8 million to expand access to cell and gene therapy clinical trials

The California Institute for Regenerative Medicine (CIRM), the state’s stem cell agency, has awarded a five-year, $8 million grant to the Keck School of Medicine of USC and Children’s Hospital Los Angeles (CHLA). …

A cell showing the enzyme BirA*G3, which tags the proteins of the "secretome" (Image courtesy of the McMahon Lab)

This mouse can’t keep a secret about the “secretome”

The “secretome” refers to proteins that are secreted by a cell, a tissue or an organism. In a new study published in Open Biology, USC Stem Cell scientist Andy McMahon and his …

Human cystic kidney organoid (Image by Cheng (Jack) Song/McMahon Lab); featured image for USC Stem Cell scientists use mini-kidney models to identify potential drugs for polycystic kidney disease

USC Stem Cell scientists use mini-kidney models to identify potential drugs for polycystic kidney disease

In a new study in Cell Stem Cell, scientists from the USC laboratory of Andy McMahon generated simple kidney-like structures called organoids, and used them to identify potential drugs to treat adult-onset …

Preet M. Chaudhary, MD, PhD, a professor of medicine, the Bloom Family Chair in Lymphoma Research, chief of the Nohl Division of Hematology (Photo courtesy of USC); featured image for Research award accelerates USC’s work on next-generation cell therapy for prostate cancer

Research award accelerates USC’s work on next-generation cell therapy for prostate cancer

One in eight men will receive a prostate cancer diagnosis in his lifetime, according to the American Cancer Society, and about one in 40 will die as a result. A USC research …

Impromptu McMahon lab meeting; featured image for USC Stem Cell: An incubator for medicine of the 21st century

USC Stem Cell: An incubator for medicine of the 21st century

Just over a decade ago, USC was a university with a few scattered stem cell biologists, and a vision for total transformation. The university was committed to designing a unique “incubator” for …

Organ of Corti; featured image for USC Stem Cell scientists explore the latent regenerative potential of the inner ear

USC Stem Cell scientists explore the latent regenerative potential of the inner ear

Scientists from the USC Stem Cell laboratory of Neil Segil have identified a natural barrier to the regeneration of the inner ear’s sensory cells, which are lost in hearing and balance disorders. …

(Image courtesy of iStock); featured image for Top scientists and research institutions propose improvements to cell- and gene-based therapy development

Top scientists and research institutions propose improvements to cell- and gene-based therapy development

Led by a USC cell and gene therapy researcher, an international coalition calls for more transparency and reproducibility in research and development of breakthrough treatments.   Scientists around the world are achieving significant …

Leonardo Morsut; featured image for USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development

USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development

Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment. To begin …

In the cGMP facility space before construction. From left: Mohamed Abou-el-Enein; Tom Buchanan; Alan S. Wayne; Caryn Lerman; and Nikos Carli. (Photo/Sergio Bianco); featured image for CHLA, Keck School, Keck Medicine and USC Norris partner on cell therapy program as construction on new facility begins

CHLA, Keck School, Keck Medicine and USC Norris partner on cell therapy program as construction on new facility begins

The essence of translational medicine is taking an idea from the drawing board and “translating” it into a real-world treatment that helps patients. The winding road of that process takes plenty of …

Xi Chen; featured image for For USC scientist Xi Chen, a chicken is more than just an egg’s way of making another egg

For USC scientist Xi Chen, a chicken is more than just an egg’s way of making another egg

USC postdoctoral researcher Xi Chen knows that you have to break a few eggs in order to grow chicken stem cells. His work on maintaining embryonic stem cells (ESC) from chicken eggs …