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Illustration by Jonathan Haase

Cycles of a fasting-mimicking diet help mice live longer, healthier

While many diets have been studied for effectiveness in preventing obesity and heart disease in both mice and humans, research on the effects and benefits of short, periodic cycles of fasting on obesity and heart health are lacking. In a new USC study on the health effects of a low-calorie diet that mimics …

mourning gecko

Aided by stem cells, a lizard regenerates a perfect tail for the first time in 250 million years

Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology)

Bérénice Benayoun receives prestigious investigator-focused grant

The Maximizing Investigators’ Research Award directly supports scientists, providing stability, flexibility and more opportunities for breakthroughs. The National Institute of General Medical Sciences has awarded an R35 Maximizing Investigators’ Research Award (MIRA) …

(Image courtesy of Children's Hospital Los Angeles)

Children’s Hospital Los Angeles awarded $6.8 million five-year grant to help lead national consortium on healthy brain development

Groundbreaking 25-site study will follow thousands of children from multiple demographics before birth through early childhood. When children are sick, clinicians can consult a known standard for how their heart, lungs and …

Neurons and muscle

Skeletal muscle grown in a dish offers new insight for neuromuscular diseases

Neuromuscular diseases are debilitating and mostly incurable, affecting 160 out of every 100,000 people worldwide. Disorders such as ALS and multiple sclerosis impact the function of muscles, causing muscle wastage and loss …

The coronal suture contains stem cells (green).

Study of skull birth defect takes it from the top

Contrary to the popular song, the neck bone is actually connected to one of 22 separate head bones that make up the human skull. These plate-like bones intersect at specialized joints called …

Organ of Corti

USC Stem Cell scientists explore the latent regenerative potential of the inner ear

Scientists from the USC Stem Cell laboratory of Neil Segil have identified a natural barrier to the regeneration of the inner ear’s sensory cells, which are lost in hearing and balance disorders. …

LA smog (Image courtesy of the Ostrow School of Dentistry of USC)

Jian Xu investigates environmental pollution’s contribution to birth defects

Jian Xu hopes to better understand the mechanisms behind environmental toxins increasing the occurrence of birth defects in order to develop new treatments or even prevent craniofacial birth defects. Nearly 120,000 babies …

(Image courtesy of iStock)

Top scientists and research institutions propose improvements to cell- and gene-based therapy development

Led by a USC cell and gene therapy researcher, an international coalition calls for more transparency and reproducibility in research and development of breakthrough treatments.   Scientists around the world are achieving significant …

Scott Fraser by Noe Montes

USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser is known for inventing new microscopes and other tools to observe living, developing embryos. But one of his lab’s most important pieces of technology filters coffee instead …

Inner ear sensory cells (left) and skin sensory cells from a one-day-old mouse

USC Stem Cell study points to a common ancestor for cells involved in hearing and touch

The sensory cells in the inner ear and the touch receptors in the skin actually have a lot in common, according to a new study from the USC Stem Cell laboratory of …

Megan McCain and family

USC Professor Megan McCain crafts an approach to tissue engineering

Megan McCain has always liked using her hands to create things, ranging from art projects to human heart cells that grow on silicon chips. “I’ve always loved building things and doing crafts, …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology)

Bérénice Benayoun receives GSA Nathan Shock New Investigator Award

The Gerontological Society of America (GSA)—the nation’s largest interdisciplinary organization devoted to the field of aging—has chosen Assistant Professor Bérénice Benayoun of the USC Leonard Davis School of Gerontology as the 2021 …

Image courtesy of the Ostrow School of Dentistry of USC

Ostrow School of Dentistry of USC awarded research training grants from National Institutes of Dental and Craniofacial Research

The prestigious five-year training grants are meant to support tomorrow’s leading thinkers in craniofacial research as they launch their academic careers. The Ostrow School of Dentistry of USC has been awarded two …

Unmesh Jadhav and Kimberly Gokoffski

The Baxter Foundation advances USC research on optic nerve disease and colorectal cancer

For over 60 years, the Donald E. and Delia B. Baxter Foundation has supported innovative biomedical research at the Keck School of Medicine of USC, each year granting $100,000 awards to two …

Justin Ichida (Photo by Chris Shinn)

AcuraStem awarded $1 million Department of Defense grant to develop ALS drug candidate

AcuraStem, a patient-based drug discovery platform company developing novel therapeutics for amyotrophic lateral sclerosis (ALS) and neurodegenerative diseases, has received an Amyotrophic Lat-eral Sclerosis Research Program (ALSRP) Therapeutic Development Award from the …

Marcella Birtele

Marcella Birtele named Choi Family Postdoctoral Fellow at USC Stem Cell

In one sense, Marcella Birtele is following in her father’s footsteps: he works as an electrician in Italy, and she studies the electrophysiology of the brain as a postdoctoral fellow in Giorgia …

Image courtesy of the Ostrow School of Dentistry of USC

A quantum leap

Ostrow jumps to fourth top-funded U.S. dental institution by the National Institute of Dental and Craniofacial Research. If a global pandemic was meant to slow researchers down in their quest for knowledge, …

Neural stem cells

Do our brains age faster than the rest of our bodies?

If you feel your brain power diminishing as you advance into middle age and beyond, blame your neural stem cells. In a new study published in Cell Stem Cell, a team led …

Pat Levitt (Photo courtesy of CHLA)

Chief Scientific Officer at Children’s Hospital Los Angeles appointed to CIRM Board

Pat Levitt, PhD, Children’s Hospital Los Angeles’ (CHLA) Chief Scientific Officer and Director of The Saban Research Institute, has been appointed to the board that oversees the California Institute for Regenerative Medicine …