The Evseenko Lab research program is designed to form a bridge between basic studies of early embryogenesis, stem cell biology, and the clinically relevant application of stem cell and small molecule-based therapies for degenerative joint disease known as osteoarthritis as well as chronic inflammatory autoimmune diseases of the joint such as rheumatoid arthritis.

Stories

Denis Evseenko leads a research team at CarthroniX that works on anti-inflammatory and regenerative drugs that may work against autoimmune disorders. (Photo by Chris Shinn); featured image for Innovators of USC: University-affiliated entrepreneurs focus on autoimmune disease

Innovators of USC: University-affiliated entrepreneurs focus on autoimmune disease

Approximately 50 million Americans suffer from autoimmune disease, according to the American Autoimmune Related Diseases Association. This includes the millions suffering from rheumatoid arthritis and lupus. Researchers at USC have developed novel …

The Interdisciplinary Stem Cell Symposium sparked collaborations. (Photo by Sergio Bianco); featured image for USC researchers converge at the Interdisciplinary Stem Cell Symposium

USC researchers converge at the Interdisciplinary Stem Cell Symposium

“The field of stem cell biology is one of our great convergence opportunities,” said USC Provost Michael Quick, addressing an audience of biologists, chemists, physicists, engineers, clinicians and many others. This diverse …

Note to self (Photo by Sergio Bianco); featured image for At the retreat for USC’s stem cell department, the students become the masters

At the retreat for USC’s stem cell department, the students become the masters

Students and trainees took center stage at the annual retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. They presented their latest research to the 180 stem cell scientists who …

Mouse joint cartilage (Image by Ben Van Handel); featured image for A joint effort to understand cartilage development

A joint effort to understand cartilage development

Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem …

A developing metacarpal joint with skeletal stem cells (green) and mature cartilage cells (red). (Image courtesy of the Evseenko Lab); featured image for Denis Evseenko receives $4 million for arthritis research

Denis Evseenko receives $4 million for arthritis research

Denis Evseenko, a stem cell researcher at the Keck School of Medicine of USC, has been awarded two grants totaling more than $4 million to support osteoarthritis research. A $3.4 million R01 …

From left, Priya Kumar and Mila Scheinberg (Photo by Cristy Lytal); featured image for Countdown to Commencement: Mila Scheinberg is an athlete, artist and future orthopedic surgeon

Countdown to Commencement: Mila Scheinberg is an athlete, artist and future orthopedic surgeon

At first glance, Mila Scheinberg’s passions seem unrelated: she has always been interested in medicine, loves to exercise and won many awards for her paintings in high school. However, in the masterpiece …

Joint cartilage (Image by Nancy Liu); featured image for Small molecule could make a big difference for arthritis patients

Small molecule could make a big difference for arthritis patients

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? USC Stem Cell scientist Denis Evseenko has reason to be optimistic. In …

Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine (Photo by Cristy Lytal); featured image for Scientists get into detail at the retreat for USC’s stem cell department

Scientists get into detail at the retreat for USC’s stem cell department

“The process of disease is about detail,” said Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s …

Human development (Image courtesy of Evseenko Lab); featured image for Whittier Foundation backs new group of research projects

Whittier Foundation backs new group of research projects

The L.K. Whittier Foundation has been a critical source of funding for cancer research at the Keck School of Medicine of USC and the USC Norris Comprehensive Cancer Center, supporting clinicians and …

From left, Gage Crump, Min Yu, Yang Chai, Joseph T. Rodgers and Denis Evseenko—all faculty in the Department of Stem Cell Biology and Regenerative Medicine—led a panel discussion about “Preparing for the faculty job market.” (Photo by Cristy Lytal); featured image for The faculty job search just got easier, thanks to two USC Stem Cell postdocs

The faculty job search just got easier, thanks to two USC Stem Cell postdocs

“I think we’re all here for the same reason,” said Michaela Patterson, a postdoc in the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC. “We’re considering …

Kidney organoid (Image by Tracy Tran/McMcMahon Lab); featured image for USC’s stem cell scientists secure the dollars to fight disease

USC’s stem cell scientists secure the dollars to fight disease

The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous …

Denis Evseenko (Photo by Cristy Lytal); featured image for Denis Evseenko receives $2.5 million from California Institute for Regenerative Medicine for osteoarthritis research

Denis Evseenko receives $2.5 million from California Institute for Regenerative Medicine for osteoarthritis research

The Keck School of Medicine of the University of Southern California (USC) is one of four institutions to receive a multi-million dollar grant from the California Institute for Regenerative Medicine (CIRM) for …

Ophir Klein, professor at the University of California, San Francisco, delivered the keynote address. (Photo by Cristy Lytal); featured image for Next generation of stem cell scientists detail their research from head to toe

Next generation of stem cell scientists detail their research from head to toe

The Stem Cell and Developmental Biology Retreat was a total body experience — covering organ systems ranging from the brain to the skeleton, from the kidney to the heart. Held on May …

Denis Evseenko (Photo by Cristy Lytal); featured image for Denis Evseenko is featured on Arthritis Now

Denis Evseenko is featured on Arthritis Now

Listen to an interview with USC Stem Cell scientist Denis Evseenko. It’s featured on Arthritis Now, a web series produced by the Arthritis National Research Foundation. The Evseenko Lab research program is …