Stories
USC researchers probe how nerves impact stem cells
It’s well known that nerves are vital for sensing the world, but researchers are now discovering how they also change the behavior of stem cells, which could have implications for regrowing teeth. …
Mini organs pave the way for understanding gastroesophageal cancer
USC researcher Dechen Lin has created miniature organs — with the hope of fighting a rare type of cancer. CANCERS THAT IMPACT THE JUNCTION of the esophagus and the stomach are rare …
Figuring out how teeth are built, one cell at a time
USC researchers look inside teeth to figure out how we might regenerate teeth in the future. TEETH ARE MARVELOUSLY COMPLICATED structures — and the way they develop is also complex. The majority …
Investigating the neighboring environment for stem cells
A long-held goal in dental research is to harness the power of stem cells to regenerate bone and dental tissue. But to do so, it’s important to fully understand the environment the …
Hunting for heart cells that can grow back after an injury
Hearts are tough organs. Over the course of a lifetime, they beat ever second of every day, keeping the entire body nourished with life-giving blood. But, even with all that stamina, heart …
Probing the genes that organize early brain development
When brains begin developing, there are a lot of moving parts — and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don’t know …
USC researchers tackle a growing problem: Dental implant disease
More than 3 million dental implants have been placed in the mouths of U.S. patients, and that number rises by 500,000 each year. While implants help many people restore their oral health, …
Baxter Foundation supports research in pediatric blindness, human brain development
The Donald E. and Delia B. Baxter Foundation is supporting researchers exploring the causes of pediatric blindness and intellectual disability research by granting $100,000 awards to two assistant professors at the Keck …
Ostrow researcher probes the roots of microcephaly, inside cells
Microcephaly is a condition where the circumference of an individual’s head is smaller than normal. It can be caused by genetic abnormalities as well as fetal exposure to drugs; alcohol; certain viruses, …
Cleft palate research continues to help patients
Associate Dean of Research Yang Chai PhD ’91, DDS ’96 has been awarded a five-year, nearly $2 million grant by the National Institute of Dental and Craniofacial Research (NIDCR) for research focused …
Ostrow researchers discover how genes for tooth roots turn on and off
To figure out how the body changes over time, researchers are increasingly looking to understand epigenetics, the study of changes in organisms caused by modification of gene expression rather than alteration of …
Researchers seek the root of tooth development
The lower two-thirds of a tooth are known as the root. Normally covered in bone, they anchor the tooth into the jaw. But the exact mechanisms and pathways that create the root …
Regrowing enamel? USC Dental Professor Janet Moradian-Oldak is on the case
Dental enamel is tricky stuff. Even though it’s the body’s hardest material, if it wears away from cavities, acidic food or drinks or overbrushing, it doesn’t regenerate. All that could change in …
USC dental researchers developing special film that could revolutionize the way peri-implantitis treated
Three million people in the United States currently have dental implants, and every year that number increases by about 500,000. But, for some, getting a dental implant is not the end of …
From teeth the spines, growing bone in new ways
Bone is crucial. After blood, it’s the most frequently transplanted tissue, with 1.6 to 2 million bone transplants performed in the United States each year.
Ostrow researcher makes strides in gel to regrow tooth enamel
Around the globe, dental cavities are the leading source of disability and pain: they affect 35 percent of the world’s population, with an economic impact in the hundreds of billions of dollars. …
A Zika surprise: African strain can do more damage than Asian strain
The Zika virus has spread to 44 countries, with thousands infected and thousands of babies born with microcephaly, a rare complication that causes small heads. But even though research dollars are being …
Stem cells may hold the key to helping patients with cleft palate
Every time we drink or breathe, the soft palate is hard at work. It acts like a trap door, allowing air to squeeze through or shutting so liquids can pass by. And …
Researcher Jian Xu earns accolades for cell fate studies
Basic science can often be far from basic—especially for Jian Xu, who believes cells are kind of like people. “In simple terms, we look at how cells determine their own fate,” said …