Hirschsprung’s Disease

Growing nerve cells in the gut

The human body has what is sometimes called a “second brain” in the digestive tract. The enteric nervous system (ENS) performs many vital functions, including coordinating the movement of food to allow …

Cardiac lymphatic vessels (red) grow alongside blood vessels (green) in the zebrafish heart. Ellen Lien's work shows that cardiac lymphatic vessels are a critical part of heart tissue regeneration after injury. This research could lead to future treatments for babies in need of heart repair. (Image courtesy of Ellen Lien)

At the heart of regeneration: Scientists reveal a new frontier in cardiac research

Story courtesy of Children’s Hospital Los Angeles One of the reasons coronary heart disease is so deadly is that fluid build-up and scarring can develop in the heart tissue. This prevents the …

Researchers at Children’s Hospital Los Angeles have made a critical advance in the field of lung research by looking at how the human lung develops at the single cell level. (Illustration/Shutterstock)

Researchers focus on lung development at its origins

The invention of interactive map applications has revolutionized wayfinding, providing an unprecedented level of information far beyond what printed road maps can offer. Researchers at Children’s Hospital Los Angeles (CHLA) are giving …

Layers of healthy human kidney cells (visible as red and green in fluorescent image) form a working filter in the new model developed by Dr. Perin and Dr. Da Sacco in the GOFARR Lab.

CHLA scientists develop first physiologically-accurate in vitro model of the human kidney glomerulus

Story courtesy of Children’s Hospital Los Angeles Kidneys work to constantly filter blood and remove toxins from the body. Conditions such as chronic kidney disease (CKD) are characterized by a reduced ability …

Melinda Smith