Dr. Wang’s lab focuses on the integration of biotechnologies in cellular and molecular engineering for the development of genetically-encoded biosensors and the application of them to visualize molecular events in live cells and animals. His lab also develops molecular sensors and transducers for the engineering of immune cells to control genetic and epigenetic activities targeting cancer immunotherapy. For example, his group engineers CAR T cells and macrophages so that they can be remotely and non-invasively controlled by ultrasound waves to recognize and eradicate tumors.  

Stories

Students at the Keck School of Medicine of USC (Photo by William Vasta); featured image for Meet the nine scholarship winners in USC’s stem cell master’s program

Meet the nine scholarship winners in USC’s stem cell master’s program

This year, philanthropic giving supported scholarships for nine students in USC’s master of science (MS) program in stem cell biology and regenerative medicine. Launched in 2014 as one of the only programs …

A time-lapse shows the Wang Lab’s EchoBack CAR T-cells attacking a large tumor mass. The green labeled points are the tumor cells. (Image by Longwei Liu/Wang Lab); featured image for New “smart” immune cells: A breakthrough for long-lasting tumor destruction

New “smart” immune cells: A breakthrough for long-lasting tumor destruction

USC Viterbi researchers have engineered a new immune cell that when activated by ultrasound can continuously sense and destroy cancer cells for extended periods. Imagine a super-charged immune cell that can launch …

USC biomedical engineers have harnessed focused ultrasound to improve CRISPR, a revolutionary tool that enables the DNA in living organisms to be modified. (Image byWang Lab and Pepper Workshop); featured image for New CRISPR toolkit to allow remote-controlled genome editing

New CRISPR toolkit to allow remote-controlled genome editing

USC Viterbi biomedical engineers harness focused ultrasound to revolutionize CRISPR’s capabilities to treat countless diseases. Thanks to CRISPR, our medical specialists will soon have unprecedented control over how they treat and prevent …

New pilot grants will forge collaborations between researchers at Keck School of Medicine of USC and the Alfred E. Mann Department of Biomedical Engineering. (Image courtesy of the USC Viterbi School of Engineering); featured image for Forging research partnerships for future medical breakthroughs

Forging research partnerships for future medical breakthroughs

New Mann Engineering in Medicine Pilot Grants program will build ongoing research collaborations between USC Viterbi School of Engineering and Keck School of Medicine of USC. The lifesaving medical discoveries and therapeutics …

Dwight C. and Hildagarde E. Baum Chair in Biomedical Engineering Peter Yingxiao Wang. Image/David Baillot, UC San Diego Jacobs School of Engineering.; featured image for Turning a tumor’s “shield” into a weapon against itself

Turning a tumor’s “shield” into a weapon against itself

USC Viterbi biomedical engineers have designed a new protein that targets and disables tumor cells’ defenses while marking cancer cells for death. Tumor cells are “cunning,” according to Peter Yingxiao Wang. They …

Building an Incubator for Medicine of the 21st Century; featured image for Building an Incubator for Medicine of the 21st Century

Building an Incubator for Medicine of the 21st Century

USC Stem Cell is pleased to introduce our new publication. We hope you’ll enjoy reflecting back on our history, while looking ahead to the transformative times to come. Read now at https://stemcell.keck.usc.edu/wp-content/themes/stemcell/incubator.

PROFESSOR LONGWEI LIU (PHOTO COURTESY OF SHANSHAN QIN); featured image for Illuminating cancer

Illuminating cancer

Longwei Liu joins USC Viterbi and the Wang Lab to uncover the secret interactions between immune cells and cancer cells with the help of fluorescent trackers.   Through the lens of a …