Chuck Murry’s lab is using stem cells to regenerate the heart muscle damaged by heart attacks. The approach is expected to enter clinical trials within the next few years.

Across USC Stem Cell, scientists are developing new approaches to help the millions of patients with heart disease, which is the leading cause of death worldwide. Each year in the U.S. alone, approximately 700,000 people die of heart disease—the cause of one in five deaths.

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Images of liver cells from aged rats elucidate cellular crosstalk in the liver. (Image by DeLeve Lab/USC)

Treatment revives old liver cells in lab study, may help prevent Alzheimer’s and heart disease

Keck School of Medicine of USC research in rats finds potential for treating diseases of aging via the liver and uncovers new insights about cell signaling. The liver’s job clearing harmful substances …

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CHLA team discovers key pathway in heart lymphatic vessel development

The findings could pave the way for better predicting lymphatic complications in children with single-ventricle heart disease. Researchers at Children’s Hospital Los Angeles have uncovered molecular signals that shape a little-understood network …

Chuck Murry in the lab

Heart health enters the future with a $28.7 million gift from the Marcus Foundation

In a landmark moment for both the treatment of heart disease and philanthropic support, The Marcus Foundation has awarded the head of USC Stem Cell, Chuck Murry, MD, PhD, $28.7 million to …

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The Marcus Foundation has awarded Chuck Murry, MD, PhD, head of USC Stem Cell, $28.7 million to advance a clinical trial testing a stem cell based therapy for heart attack damage. The trial will begin at Keck Hospital in 2027 in partnership with the USC Cardiac and Vascular Institute, with a second site at the University of Washington. About 18 patients who have experienced a severe heart attack will take part in this first in human safety and feasibility study.
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