Dr. Quadrato’s laboratory focuses on understanding the cellular and molecular basis of human brain development and disease. By combining the use of emerging models of the human brain with single cell omics approaches, the laboratory is aiming to identify cell type specific disease mechanisms, and above all, new treatments for human neurodevelopmental disorders.
Genes aren’t the sole driver instructing cells to build multicellular structures, tissues, and organs. In a new paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist …
To democratize access to lab-grown organ-like structures known as organoids and other advanced stem cell and transcriptomic technologies, USC will launch the CIRM ASCEND Center, dedicated to “Advancing Stem Cell Education and …
In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that …
USC Stem Cell is pleased to introduce our new publication. We hope you’ll enjoy reflecting back on our history, while looking ahead to the transformative times to come. Read now at https://stemcell.keck.usc.edu/wp-content/themes/stemcell/incubator.
New research shows that variants of SYNGAP1, a gene previously thought only to affect synapses between mature neurons, may disrupt early development in the brain’s cortex, a region involved in higher-order cognitive …
This year, ten students earned scholarships that enabled them to attend USC’s master’s program in stem cell biology and regenerative medicine, one of the only programs of its kind in the United …
A pair of young scientists picked up a piece of driftwood and thoughtfully traced a series of letters in the wet sand of Ventura Beach. The word “microglia”—referring to the immune cells …
For USC cancer researcher Min Yu, starting her lab meant building a culture of like-minded scientists. When she first joined the university as an assistant professor of stem cell biology and regenerative …
In one sense, Marcella Birtele is following in her father’s footsteps: he works as an electrician in Italy, and she studies the electrophysiology of the brain as a postdoctoral fellow in Giorgia …
Giorgia Quadrato, an assistant professor in USC’s Department of Stem Cell Biology and Regenerative Medicine, was recently awarded an Edward Mallinckrodt Foundation (EMF) grant to further her research about modeling human brain …
The human brain is an incredibly complex organ to study in its living tissue form. Researchers cannot experiment on human tissue directly, and animal models are often too different to human physiology …
Maybe a child misses a developmental milestone, such as rolling over, or saying that first word. Perhaps the child also falls down due to seizures, or develops symptoms of an autism spectrum …
The Donald E. and Delia B. Baxter Foundation is supporting researchers exploring the causes of pediatric blindness and intellectual disability research by granting $100,000 awards to two assistant professors at the Keck …
Growing stem cells isn’t just something junior faculty do in the lab. Eight of the junior faculty in the Department of Stem Cell Biology and Regenerative Medicine recently welcomed new babies into …
If anyone has a clear vision of the power of stem cell cures, it’s Anna Kuehl. She suffered a retina-wrecking disease that cost her much of her sight before USC physicians surgically …
Giorgia Quadrato loves a good challenge. That’s why USC’s newest assistant professor of stem cell biology and regenerative medicine currently spends her time growing 3D networks of human nerve cells, called brain …
“The field of stem cell biology is one of our great convergence opportunities,” said USC Provost Michael Quick, addressing an audience of biologists, chemists, physicists, engineers, clinicians and many others. This diverse …