The hair follicle (HF) is an attractive miniorgan for studying adult stem cell biology and behavior because of its unique location: the HF bulge area. Using transgenic mouse model, studies from Krzysztof Kobielak’s group provide new insight into the molecular mechanisms of HF stem cell maintenance and activation by intra-cell antagonistic competition between BMP and Wnt signaling pathways.
The study is published in PNAS.
