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In the head of this 5-day-old zebrafish, one enhancer is visible in cartilage (magenta) while another is active in the tissue surrounding the skeleton (green). (Image by Kelsey Elliott/Crump Lab/USC Stem Cell); featured image for NIH awards $3.3 million grant to study the role of gene regulation in congenital anomalies

NIH awards $3.3 million grant to study the role of gene regulation in congenital anomalies

The project will use zebrafish and other species to understand the logic and evolution of craniofacial development. A research team led by Gage Crump, PhD, at the Keck School of Medicine of …

Healthy growth plate; featured image for USC researcher probes the cells that sustain growth plates

USC researcher probes the cells that sustain growth plates

Assistant Professor Zhaoyang Liu hopes her research will not only help people with growth limitations but also advance the understanding of craniofacial biology. HOW DOES THE GROWTH PLATE — the region of …

Knee injection; featured image for Clinical trial evaluates investigational injection for knee osteoarthritis

Clinical trial evaluates investigational injection for knee osteoarthritis

Keck Medicine of USC studies the safety of a USC-developed therapy and its potential effects on cartilage deterioration in the knee joint. Keck Medicine of USC has launched a clinical trial testing …

Teeth with lesions; featured image for Think enamel erosion is irreversible? Think again.

Think enamel erosion is irreversible? Think again.

After decades of research, Ostrow faculty member Janet Moradian-Oldak prepares to bring a short peptide that can generate a biomimetic version of tooth enamel to market. FOR DECADES, PROFESSOR JANET MORADIAN-OLDAK has …

Thymus; featured image for Thymus-derived hormone may help suppress age-related inflammation

Thymus-derived hormone may help suppress age-related inflammation

In animal models, researchers from the Keck School of Medicine of USC found that targeting the thymus can reduce age-related inflammation and improve cancer outcomes. Chronic, low-grade inflammation in the body—a phenomenon …

Man pressing his hand against a painful jaw; featured image for USC researchers study impacts of synovial lymphatic system on TMJ

USC researchers study impacts of synovial lymphatic system on TMJ

A recent Nature Communications article sheds light on how fluid drainage systems may worsen jaw pain in the 5 to 8 percent of Americans affected by temporomandibular joint disorders. Problems with jaw …

2026 USC CIRM COMPASS graduates (Photo by Amor Mathershed); featured image for Undergraduate stem cell research takes the spotlight at USC CIRM COMPASS symposium

Undergraduate stem cell research takes the spotlight at USC CIRM COMPASS symposium

USC Stem Cell prepares undergraduates to present research and become the regenerative medicine workforce of the future. Stem cell research took center stage at the year-end symposium for the USC CIRM COMPASS …

Heliya Ziaei (Photo courtesy of the Ostrow School of Dentistry of USC); featured image for Driven to impact

Driven to impact

Powered by her Ostrow experience, Heliya Ziaei is well positioned to blend research and patient care as a clinician-scientist. Though Heliya Ziaei, PhD ’26, arrived at the Herman Ostrow School of Dentistry …

Impromptu McMahon lab meeting; featured image for USC honors stem cell leader Andy McMahon with a lifetime achievement award

USC honors stem cell leader Andy McMahon with a lifetime achievement award

The award recognizes McMahon’s career advancing developmental biology and building scientific communities, including USC Stem Cell. As a pioneer in developmental biology and founder of USC Stem Cell, Andy McMahon, PhD, FRS, …

Red indicates mouse embryonic stem cells and green indicates mouse epiblast stem cells. The two cell types were co-cultured under GSK3α inhibition and maintained their distinct identities. (Image by Duo Wang/Ying Lab/USC Stem Cell); featured image for A “stemness checkpoint” helps control stem cell identity

A “stemness checkpoint” helps control stem cell identity

Building on the concept that blocking differentiation into specialized cell types maintains stem cells, USC and NIH scientists identify GSK3α as a checkpoint across diverse stem cell types. A study published in …

The new joint department will accelerate health care innovation. (USC Photos); featured image for USC announces joint biomedical engineering department, bridging medical and engineering schools

USC announces joint biomedical engineering department, bridging medical and engineering schools

Building on decades of collaboration between the USC Viterbi School of Engineering and the Keck School of Medicine of USC, the department reimagines the expansion of biomedical engineering into medicine. The Keck …

When not juggling the myriad tasks required as Ostrow's newest Dean, Yang Chai feels most at peace, cultivating the gardens at his L.A. home. (Photo by Christina Gandolfo)

Growing a garden of academic excellence

His path to USC from China led the clinician-scientist through resilience and growth — and now the Ostrow Dean will nurture learning, patient care and research into the future. On Sundays, Ostrow’s …

Hands holding landscape iPad; featured image for New federal grant to help researchers explore better treatment options for temporomandibular disorders

New federal grant to help researchers explore better treatment options for temporomandibular disorders

The $4.3-million NIDCR grant will help clinicians build upon previous work to improve patient outcomes for those suffering with TMD pathology. There are few joints as complex as the jaws — they …

Megan McCain's lab (Photo by Chris Shinn)

USC launches a new Center for Stem Cell Engineering on the Health Sciences Campus

A collaboration between the Keck School of Medicine of USC and the USC Viterbi School of Engineering, the center will use stem cell engineering to uncover disease mechanisms and advance new therapies. …

An implantable retinal patch for restoring vision is one of the university’s most cited examples of therapeutic success. (Illustration/aDerek Brahney); featured image for From lab to launch: Inside USC’s fast-growing ecosystem of health startups

From lab to launch: Inside USC’s fast-growing ecosystem of health startups

From patches that restore vision to compounds that kill brain tumors, drug and device discoveries by USC researchers are reaching patients faster than ever before. Ten years ago, two pediatric heart specialists …

The National Institute on Aging has awarded a $6.5 million, five-year grant to Cedars-Sinai, USC and UCLA to create the Los Angeles Claude D. Pepper Older Americans Independence Center. (USC Photo/Nat Avunjian); featured image for New NIA-funded center to help older adults live longer, healthier lives

New NIA-funded center to help older adults live longer, healthier lives

A new Los Angeles research hub will take on one of today’s most pressing challenges: helping people live not just longer, but healthier and more independent lives as they age. The National …

Embryonic stem cells from a Barred Plymouth Rock chicken (Image by Xi Chen/Ying Lab/USC Stem Cell); featured image for USC Stem Cell-led study generates authentic embryonic stem cells from birds

USC Stem Cell-led study generates authentic embryonic stem cells from birds

Scientists discover that egg yolk is a key to establishing authentic embryonic stem cells from chickens and seven other avian species, as reported in Nature Biotechnology. Egg whites may be perfect for …

; featured image for USC Stem Cell students and trainees win $15,000 collaborative research grants

USC Stem Cell students and trainees win $15,000 collaborative research grants

When learning to become a great scientist, the most important lesson might be how to collaborate. To encourage this essential skill, for the past decade, USC Stem Cell has awarded one-year challenge …

USC PhD student Shuwan Liu (right) with ASBMR president; featured image for USC Stem Cell PhD student Shuwan Liu receives award from the American Society for Bone and Mineral Research

USC Stem Cell PhD student Shuwan Liu receives award from the American Society for Bone and Mineral Research

Which signals drive cells to heal large-scale bone injuries? For her research into this question, USC Stem Cell PhD student Shuwan Liu has won a 2025 Young Investigator Award from the American …

; featured image for Why aging matters for bone healing: New clues from the rib

Why aging matters for bone healing: New clues from the rib

A resected rib in a young person can grow back with surprising ease—even if a large piece is missing. This remarkable healing ability was observed by Janice S. Lee, principal investigator of …