A special protein helps embryonic stem cells keep their options open
In the ongoing quest to understand how embryonic stem cells (ESCs) retain their ability to differentiate into virtually any kind of cell, USC faculty member Qi-Long Ying and a team of researchers …
USC announces winners of first Regenerative Medicine Initiative awards
Three newly assembled disease teams within USC Stem Cell will take the early steps this year that might lead to future stem-cell based therapies for certain forms of deafness, bone defects and …
Stem cells found in gum tissue can fight inflammatory disease
Stem cells found in mouth tissue can not only become other types of cells but can also relieve inflammatory disease, according to a new Ostrow School of Dentistry of USC study in …
USC study sheds light on stem cell reprogramming
Researchers are learning how to turn regular cells into stem cells, a process called reprogramming. However, some of the mechanisms of the process remain unknown, such as why only a small proportion of the cells can be reprogrammed. Researchers have at least part of the answer: the structure of genes.
Common genetic disease linked to father’s age
Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan syndrome are so common—a mutation, which causes the disease, disproportionately increases a normal father’s production of …
USC hosts mini-symposium on musculoskeletal development and repair
With its combination of bone, muscle, joints and more, the human musculoskeletal system is a complicated tangle of connections that can be difficult to repair. That was the challenge facing a panel …
New method to treat chemo-related jaw bone necrosis
Over the last decade, osteonecrosis of the jaw (ONJ) has emerged as a devastating and debilitating condition of cancer patients receiving high doses of antiresorptive chemotherapy (bisphosphonates and denosumab). ONJ currently has …
Interview with Sir John Gurdon
Sir John Gurdon, a Nobel Prize-winning biologist whose experiments in the field of cloning laid the foundation for modern stem cell research, visited the USC Health Sciences Campus on May 16. He …
Nobel Laureate discusses history of cloning
Cells can be stubborn things. A skin cell resists changing into a liver cell, and a heart cell wants to remain a heart cell. But with the right kind of manipulation, they …
Alligator stem cell study gives clues to tooth regeneration
Alligators may help scientists learn how to stimulate tooth regeneration in people, according to new research led by the Keck School of Medicine of USC. For the first time, a global team …
Birds of a feather flock together for stem cell research
To eventually use stem cells in regenerative medicine, scientists need to understand how stem cells become organized into particular tissue patterns and shapes. With that in mind, researchers at USC recently found …
Ostrow School investigators recognized for research
The International Association of Dental Research (IADR) honored two scientists from the Ostrow School of Dentistry of USC at the association’s general session opening ceremonies on March 20 in Seattle. Professor Songtao …
Nobel laureate to speak on stem cells at HSC
Nobel laureate Sir John Gurdon will speak on “From Nuclear Transplantation to Prospects for Cell Replacement” on May 16 at noon in the Aresty Auditorium of the Harlyne J. Norris Cancer Research …
Probing the power of stem cells
Piece by missing piece, scientists at the Keck School of Medicine of USC are deciphering the powerful gene regulatory circuit that maintains and controls the potential of embryonic stem cells (ESCs) to …
Unraveling the mystery of pluripotency in embryonic stem cells
Using advanced sequencing technology, USC Stem Cell faculty member Wange Lu, in collaboration with Kai Wang of the USC Zilkha Neurogenetics Institute, explores the mystery of pluripotency by mapping out the interaction …
McMahon discusses central role of stem cell biology in medicine of the future
USC scored a major coup when it brought scientist Andrew McMahon to the Keck School of Medicine of USC from Harvard University, where he had served for almost two decades as a …
An important factor identified in reprogramming
How is the stem cell state programmed? A new study in Qi-Long Ying’s group at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC highlights the role …
Adult hair stem cell fate regulated by competition between two signaling pathways
The hair follicle (HF) is an attractive miniorgan for studying adult stem cell biology and behavior because of its unique location: the HF bulge area. Using transgenic mouse model, studies from USC …
USC launches Regenerative Medicine and Stem Cell Research Initiative
A new USC initiative has been introduced to support collaborative research in regenerative medicine and stem cell biology across the university, facilitating the critical move from basic research into clinical applications.
Discovery of genetic clues may lead to better grasp of birth defects
Using cutting-edge time-lapse photography, Keck School of Medicine researchers have discovered clues to the development of the head at the cellular level, which could point scientists to a better understanding of how …