Stopping arthritis before it starts
A novel off-the-shelf bio-implant containing embryonic stem cells has the potential to revolutionize the treatment of cartilage injuries More than a million Americans undergo knee and hip replacements each year. It’s a …
USC collaboration helps FaceBase reach 1,000-dataset milestone
The data repository allows craniofacial scientists to share data, which could ultimately lead to improved care for patients with craniofacial developmental disorders. Rapid technological development in the past decade has allowed scientists …
USC Stem Cell: An incubator for medicine of the 21st century
Just over a decade ago, USC was a university with a few scattered stem cell biologists, and a vision for total transformation. The university was committed to designing a unique “incubator” for …
Cycles of a fasting-mimicking diet help mice live longer, healthier
While many diets have been studied for effectiveness in preventing obesity and heart disease in both mice and humans, research on the effects and benefits of short, periodic cycles of fasting on obesity and heart health are lacking. In a new USC study on the health effects of a low-calorie diet that mimics …
Aided by stem cells, a lizard regenerates a perfect tail for the first time in 250 million years
Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, …
Bérénice Benayoun receives prestigious investigator-focused grant
The Maximizing Investigators’ Research Award directly supports scientists, providing stability, flexibility and more opportunities for breakthroughs. The National Institute of General Medical Sciences has awarded an R35 Maximizing Investigators’ Research Award (MIRA) …
Skeletal muscle grown in a dish offers new insight for neuromuscular diseases
Neuromuscular diseases are debilitating and mostly incurable, affecting 160 out of every 100,000 people worldwide. Disorders such as ALS and multiple sclerosis impact the function of muscles, causing muscle wastage and loss …
Study of skull birth defect takes it from the top
Contrary to the popular song, the neck bone is actually connected to one of 22 separate head bones that make up the human skull. These plate-like bones intersect at specialized joints called …
Jian Xu investigates environmental pollution’s contribution to birth defects
Jian Xu hopes to better understand the mechanisms behind environmental toxins increasing the occurrence of birth defects in order to develop new treatments or even prevent craniofacial birth defects. Nearly 120,000 babies …
Top scientists and research institutions propose improvements to cell- and gene-based therapy development
Led by a USC cell and gene therapy researcher, an international coalition calls for more transparency and reproducibility in research and development of breakthrough treatments. Scientists around the world are achieving significant …
USC Professor Scott E. Fraser redefines impossible problems
USC Professor Scott E. Fraser is known for inventing new microscopes and other tools to observe living, developing embryos. But one of his lab’s most important pieces of technology filters coffee instead …
USC Professor Megan McCain crafts an approach to tissue engineering
Megan McCain has always liked using her hands to create things, ranging from art projects to human heart cells that grow on silicon chips. “I’ve always loved building things and doing crafts, …
Bérénice Benayoun receives GSA Nathan Shock New Investigator Award
The Gerontological Society of America (GSA)—the nation’s largest interdisciplinary organization devoted to the field of aging—has chosen Assistant Professor Bérénice Benayoun of the USC Leonard Davis School of Gerontology as the 2021 …
Ostrow School of Dentistry of USC awarded research training grants from National Institutes of Dental and Craniofacial Research
The prestigious five-year training grants are meant to support tomorrow’s leading thinkers in craniofacial research as they launch their academic careers. The Ostrow School of Dentistry of USC has been awarded two …
Could stem cell- or molecular-based treatment be the solution to temporomandibular joint disorders?
A new study, led by Amy Merrill-Brugger, could lead to new treatments for the common disorder. Our jaws allow us to talk, chew, swallow, sing and even yawn. All these activities require …
USC researchers regenerate skull tissue using stem cells and 3-D printed scaffolding in swine
Every year, surgeons perform more than 5,000 cranioplasties—surgeries that restore cranial defects—on patients who have experienced critical size cranial defects resulting from congenital defects, head trauma or tumor removals. Traditional materials used …
As a graduate of USC’s stem cell master’s program, Eli Bosnoyan celebrates a Trojan Family that stretches from Syria to South LA
When Eli Bosnoyan first set foot on the USC campus, he was a six-year-old boy from Aleppo, Syria, visiting relatives in Los Angeles during his summer vacation. “I was with my brother,” …
A quantum leap
Ostrow jumps to fourth top-funded U.S. dental institution by the National Institute of Dental and Craniofacial Research. If a global pandemic was meant to slow researchers down in their quest for knowledge, …
USC celebrates Robert E. Maxson’s lifetime of achievement and adventure
USC Emeritus Professor Robert E. Maxson has an understated explanation for why he’s flown so many planes, sailed so many boats, skied so many mountains, played so many guitars, taken so many …
USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development
Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment. To begin …