News & Events

Muscles and Skeleton News
Nelson Poliran, Jr.; featured image for Where are they now? Stem cell master’s program alumnus Nelson Poliran, Jr., a dentist in rural New Mexico

Where are they now? Stem cell master’s program alumnus Nelson Poliran, Jr., a dentist in rural New Mexico

In this series of alumni profiles, we highlight graduates of USC’s master of science program in stem cell biology and regenerative medicine. Our accomplished alumni have pursued many different paths—ranging from a …

Jian Xu (Photo by John Skalicky); featured image for Ostrow faculty member Jian Xu does craniofacial biology with heart

Ostrow faculty member Jian Xu does craniofacial biology with heart

The researcher was recently promoted to the rank of Associate Professor of Dentistry with tenure. TO SOME, IT MIGHT SEEM UNUSUAL that Jian Xu, whose PhD research focused on cardiac hypertrophy and …

Clockwise from top left, Miao Cui, Yulia Shwartz, Olena Zhulyn, and Kyle McCracken; featured image for Stem cell scientists explore the mysteries of regeneration at the Junior Faculty Candidate Seminar and Symposium

Stem cell scientists explore the mysteries of regeneration at the Junior Faculty Candidate Seminar and Symposium

How can we regenerate tissues that are damaged, lost or diseased in the human body? This was the central question driving the four scientists who presented their research at the Junior Faculty …

Spine from a healthy mouse (left) and a mouse with genetically disrupted cartilage progenitor cells (Image by Dawei Geng and Tea Jashashvili); featured image for Arthritis-related gene also regenerates cartilage in joints and growth plates

Arthritis-related gene also regenerates cartilage in joints and growth plates

The IL-6 family of proteins has a bad reputation: it can promote inflammation, arthritis, autoimmune disease and even cancer. However, a new USC-led study published in Communications Biology reveals the importance of …

Confocal microscopy image of an adult zebrafish head with neural crest-derived cells in red. The Crump lab has used single-cell sequencing to understand how these cells build and repair the head skeleton, with implications for understanding human craniofacial birth defects and improving repair of skeletal tissues. (Image by Hung-Jhen Chen/Crump Lab); featured image for A crowning achievement in understanding head development

A crowning achievement in understanding head development

Cranial neural crest cells, or CNCCs, contribute to many more body parts than their humble name suggests. These remarkable stem cells not only form most of the skull and facial skeleton in …

Frank Petrigliano, MD, and Denis Evseenko, MD, PhD, have been collaborating on medical innovations to help heal and even regenerate damaged joints. (Photo/Ricardo Carrasco III); featured image for Stopping arthritis before it starts

Stopping arthritis before it starts

A novel off-the-shelf bio-implant containing embryonic stem cells has the potential to revolutionize the treatment of cartilage injuries More than a million Americans undergo knee and hip replacements each year. It’s a …

Image courtesy of the Ostrow School of Dentistry of USC; featured image for USC collaboration helps FaceBase reach 1,000-dataset milestone

USC collaboration helps FaceBase reach 1,000-dataset milestone

The data repository allows craniofacial scientists to share data, which could ultimately lead to improved care for patients with craniofacial developmental disorders. Rapid technological development in the past decade has allowed scientists …

Impromptu McMahon lab meeting; featured image for USC Stem Cell: An incubator for medicine of the 21st century

USC Stem Cell: An incubator for medicine of the 21st century

Just over a decade ago, USC was a university with a few scattered stem cell biologists, and a vision for total transformation. The university was committed to designing a unique “incubator” for …

Illustration by Jonathan Haase; featured image for Cycles of a fasting-mimicking diet help mice live longer, healthier

Cycles of a fasting-mimicking diet help mice live longer, healthier

While many diets have been studied for effectiveness in preventing obesity and heart disease in both mice and humans, research on the effects and benefits of short, periodic cycles of fasting on obesity and heart health are lacking. In a new USC study on the health effects of a low-calorie diet that mimics …

mourning gecko; featured image for Aided by stem cells, a lizard regenerates a perfect tail for the first time in 250 million years

Aided by stem cells, a lizard regenerates a perfect tail for the first time in 250 million years

Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology); featured image for Bérénice Benayoun receives prestigious investigator-focused grant

Bérénice Benayoun receives prestigious investigator-focused grant

The Maximizing Investigators’ Research Award directly supports scientists, providing stability, flexibility and more opportunities for breakthroughs. The National Institute of General Medical Sciences has awarded an R35 Maximizing Investigators’ Research Award (MIRA) …

Neurons and muscle; featured image for Skeletal muscle grown in a dish offers new insight for neuromuscular diseases

Skeletal muscle grown in a dish offers new insight for neuromuscular diseases

Neuromuscular diseases are debilitating and mostly incurable, affecting 160 out of every 100,000 people worldwide. Disorders such as ALS and multiple sclerosis impact the function of muscles, causing muscle wastage and loss …

The coronal suture contains stem cells (green).; featured image for Study of skull birth defect takes it from the top

Study of skull birth defect takes it from the top

Contrary to the popular song, the neck bone is actually connected to one of 22 separate head bones that make up the human skull. These plate-like bones intersect at specialized joints called …

LA smog (Image courtesy of the Ostrow School of Dentistry of USC); featured image for Jian Xu investigates environmental pollution’s contribution to birth defects

Jian Xu investigates environmental pollution’s contribution to birth defects

Jian Xu hopes to better understand the mechanisms behind environmental toxins increasing the occurrence of birth defects in order to develop new treatments or even prevent craniofacial birth defects. Nearly 120,000 babies …

(Image courtesy of iStock); featured image for Top scientists and research institutions propose improvements to cell- and gene-based therapy development

Top scientists and research institutions propose improvements to cell- and gene-based therapy development

Led by a USC cell and gene therapy researcher, an international coalition calls for more transparency and reproducibility in research and development of breakthrough treatments.   Scientists around the world are achieving significant …

Scott Fraser by Noe Montes; featured image for USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser is known for inventing new microscopes and other tools to observe living, developing embryos. But one of his lab’s most important pieces of technology filters coffee instead …

Megan McCain and family; featured image for USC Professor Megan McCain crafts an approach to tissue engineering

USC Professor Megan McCain crafts an approach to tissue engineering

Megan McCain has always liked using her hands to create things, ranging from art projects to human heart cells that grow on silicon chips. “I’ve always loved building things and doing crafts, …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology); featured image for Bérénice Benayoun receives GSA Nathan Shock New Investigator Award

Bérénice Benayoun receives GSA Nathan Shock New Investigator Award

The Gerontological Society of America (GSA)—the nation’s largest interdisciplinary organization devoted to the field of aging—has chosen Assistant Professor Bérénice Benayoun of the USC Leonard Davis School of Gerontology as the 2021 …

Image courtesy of the Ostrow School of Dentistry of USC; featured image for Ostrow School of Dentistry of USC awarded research training grants from National Institutes of Dental and Craniofacial Research

Ostrow School of Dentistry of USC awarded research training grants from National Institutes of Dental and Craniofacial Research

The prestigious five-year training grants are meant to support tomorrow’s leading thinkers in craniofacial research as they launch their academic careers. The Ostrow School of Dentistry of USC has been awarded two …

Image courtesy of the Ostrow School of Dentistry of USC; featured image for Could stem cell- or molecular-based treatment be the solution to temporomandibular joint disorders?

Could stem cell- or molecular-based treatment be the solution to temporomandibular joint disorders?

A new study, led by Amy Merrill-Brugger, could lead to new treatments for the common disorder. Our jaws allow us to talk, chew, swallow, sing and even yawn. All these activities require …