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Request for Proposals: Broad Innovation Awards for Collaborative Research Teams

Computational Biology and Single Cell Approaches to Stem Cell Systems Through the generous support of the Eli and Edythe Broad Foundation, we are pleased to announce a new collaborative research initiative in Computational Biology and Single Cell Approaches to Stem Cell Systems. The goal of funding is to seed new collaborative projects with the expectation …

Breakthrough in testosterone-producing cells could lead to treatment for “low T”

USC researchers have successfully grown human, testosterone-producing cells in the lab, paving the way to someday treat low testosterone with personalized replacement cells. In Monday’s Proceedings of the National Academy of Sciences, scientists describe how they transformed stem cells into functioning Leydig cells — the cells in the testes that produce the male sex hormone. “Our …

Request for Proposals: Broad Clinical Research Fellows

A new gift from The Eli and Edythe Broad Foundation enabled renewal of the Eli and Edythe Broad Clinical Research Fellows at USC. We plan to fund up to three positions. The fellows must have completed their MD or MD/PhD training, currently be in their residency or fellowship program and hold a license to practice …

Bangyan Stiles, PhD, and colleagues from the USC Viterbi School of Engineering were awarded a three-year National Institutes of Health (NIH) project grant in the amount of $636,141. Photo by Ed Carreon.

NIH grant awarded to Bangyan Stiles and colleagues

Bangyan Stiles, PhD, professor of pharmacology and pharmaceutical sciences at the USC School of Pharmacy, and colleagues from the USC Viterbi School of Engineering were awarded a three-year, $636,141 National Institutes of Health (NIH) grant for the project “Robust Inference in the Presence of Data Heterogeneity and Structured Missing Data.” Sze-chuan Suen, PhD and Meisam …

Lindsey Michaela Katie Joanna SELFIE

Meet six USC Stem Cell postdocs-turned-professors

Only 23 percent of biomedical PhD holders eventually land tenure-track faculty positions, according to a report by the National Institutes of Health Biomedical Research Workforce Working Group. Beating these odds, six postdoctoral trainees from USC’s Department of Stem Cell Biology and Regenerative Medicine recently landed coveted jobs as tenure-track assistant professors: Lori O’Brien at the …

Assistant Professor Jianfu Chen is working on ways to understand how the disorder is regulated in genes, and hopes one day to find treatments.

Ostrow researcher probes the roots of microcephaly, inside cells

Microcephaly is a condition where the circumference of an individual’s head is smaller than normal. It can be caused by genetic abnormalities as well as fetal exposure to drugs; alcohol; certain viruses, such as Zika virus; or toxins during pregnancy. It’s rare — there are fewer than 200,000 cases a year in the United States. …

USC Stem Cell scientist Thomas Lozito looks to lizards in hopes of healing humans

Some students sell blood plasma to make extra cash during graduate school. Thomas Lozito, a new assistant professor of orthopaedic surgery and stem cell biology and regenerative medicine at USC, sold poison dart frogs to ward off the impecunity of the PhD years. “When I was in high school and all the way up to …

USC researcher Yang Chai has received another five-year grant to bolster his research into the causes of one of the most common congenital birth defects.

Cleft palate research continues to help patients

Associate Dean of Research Yang Chai PhD ’91, DDS ’96 has been awarded a five-year, nearly $2 million grant by the National Institute of Dental and Craniofacial Research (NIDCR) for research focused on better understanding the molecular regulatory mechanisms of cleft palate. It’s the fourth time the grant has been renewed, continuously supporting this research …

Frank Petrigliano

Frank Petrigliano named chief of USC Epstein Family Center for Sports Medicine

The USC Epstein Family Center for Sports Medicine at Keck Medicine of USC, which specializes in treating sports-related and recreational injuries affecting the shoulder, knee, hip and elbow, recently announced the appointment of Frank Petrigliano, MD, as the chief of the center and head team physician for the Los Angeles Kings hockey team. He also …

USC brings the world’s largest stem cell conference to Los Angeles

For the first time ever, the City of Los Angeles hosted the world’s largest stem cell conference. By choosing Los Angeles as the host city for this major annual meeting, the International Society for Stem Cell Research (ISSCR) acknowledged the city’s growing importance as a hub for the biosciences, as well as the world-class research …

USC researchers receive $12.5 million grant for craniofacial research data-sharing endeavor

Nearly half of all birth defects involve the face and skull and, for the most part, scientists remain unclear as to why most occur. To better serve families at risk for these conditions, scientists need a comprehensive and systematic understanding of how the faces of healthy children form and what goes wrong to cause common …

The discovery could change the way dental implants are placed, allowing dentists to regenerate tooth roots that better integrate with jaw bone structures.

Ostrow researchers discover how genes for tooth roots turn on and off

To figure out how the body changes over time, researchers are increasingly looking to understand epigenetics, the study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself. This scientific endeavor extends to teeth as well. Associate Dean of Research Yang Chai PhD ’91, DDS ’96 has …

Jean Rosenbaum

France-USA Stem Cell Symposium gathers la crème de la crème

Science was the common language at the first France-USA Stem Cell Symposium, held at the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC. The event brought together over 100 stem cell scientists from France and the United States on the eve of the field’s largest annual conference—the International …

Navigage, Rose Hills Foundations support Berenice Benayoun

From catching cognitive impairment earlier to understanding the genetics of age-related disease and health disparities, USC Leonard Davis School of Gerontology faculty conduct exciting research supported by organizations committed to helping others. The Navigage Foundation awarded grants for pilot research projects led by USC Leonard Davis faculty members Berenice Benayoun and Mireille Jacobson. Jacobson, an …

From babies to senior citizens, USC Stem Cell researcher Denis Evseenko is working for better outcomes

When Denis Evseenko was still a student at Novosibirsk State Medical University in southern Siberia, he began pondering the meaning of life. “I was reading a lot of philosophic things [saying that] everything is pointless because you will die,” he said. “And the only one thing that makes it not completely pointless is that you …

$10 million gift from Broad Foundation advances USC stem cell research on aging-associated disease

USC’s groundbreaking stem cell research and training programs have received a major boost thanks to a $10 million gift from the Eli and Edythe Broad Foundation. The donation is part of the foundation’s latest $30 million funding initiative to support its namesake Eli and Edythe Broad stem cell research centers at USC, UCLA and University …

Janet Oldak

Moradian-Oldak receives Distinguished Scientist Award

Professor Janet Moradian-Oldak received a 2019 Basic Research in Biological Mineralization Award at the International Association for Dental Research’s (IADR) General Session and Exhibition in mid-June. The award — one of 17 Distinguished Scientist Awards — is one of the most prestigious awards bestowed by the IADR. It is meant to stimulate, encourage and recognize …

USC Stem Cell junior faculty balance babies with biomedical research

Growing stem cells isn’t just something junior faculty do in the lab. Eight of the junior faculty in the Department of Stem Cell Biology and Regenerative Medicine recently welcomed new babies into their families—more than half of them within the past year. Here, our junior faculty parents share their joy and wisdom about balancing career …

From restoring sight to reversing brain damage, USC stem cell researchers are making life-changing discoveries

If anyone has a clear vision of the power of stem cell cures, it’s Anna Kuehl. She suffered a retina-wrecking disease that cost her much of her sight before USC physicians surgically implanted stem cells to restore her ability to see. Today, she can see the letters on computer keys, use her iPhone and read …

Yang Chai bridges the gap from the lab bench to the dental chair

As a young oral surgeon in China, Yang Chai often operated on babies born with cleft lips or palates. “You talk to the parents, and they were very emotional and trying find out why their kid got this cleft palate or other malformation in the face,” he said. “You can tell them all the statistics—one …

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