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The inferior alveolar nerve provides a niche for stem cells that maintain incisor homeostasis. When the nerve is severed, homeostasis is disrupted and within one month the affected incisor becomes chalky and breaks. (Photos/courtesy of Center for Craniofacial Molecular Biology)

Dental study provides wealth of stem cell details

An Ostrow School of Dentistry of USC study has uncovered new details on how bundles of nerves and arteries interact with stem cells and also showcases revolutionary techniques for following the cells …

SJ Gao (Photo courtesy of USC)

Viral molecules responsible for causing AIDS-related cancer

Using a rat stem cell model, USC researcher S. J. Gao, PhD and colleagues have identified a critical cancer-causing component in the virus that causes Kaposi’s sarcoma, the most common cancer among …

Valter Longo (Photo by Dietmar Quistorf)

Valter Longo seeks a recipe for longevity

Video by the USC Davis School of Gerontology Valter Longo, PhD, principal investigator with USC Stem Cell, is out to prove that gerontology is a young man’s game — just like rock …

USC scientist Krzysztof Kobielak, MD, PhD, and postdoctoral fellow Eve Kandyba, PhD (Photo by Cristy Lytal)

Stem cells offer clues to reversing receding hairlines

Regenerative medicine may offer ways to banish baldness that don’t involve toupees. The lab of USC scientist Krzysztof Kobielak, MD, PhD has published a trio of papers in the journals Stem Cells …

A series of mouse skulls (Image by Hu Zhao)

Winner of the December 2013 USC Stem Cell Image of the Month Contest

Dr. Andy McMahon and the judges of the USC Stem Cell Image of the Month contest would like to congratulate our December 2013 winner, Dr. Hu Zhao, DDS, PhD, a research associate …

AAAS logo

Robert Maxson and five other USC professors named fellows of AAAS

Robert Maxson Jr., an executive committee member of USC Stem Cell, is one of six USC scientists to be elected fellow of the American Association for the Advancement of Science (AAAS).

From left to right: Marvin Nelson, MD, MBA, Rex Moats, PhD, Brent Polk, MD, Elizabeth Garrett, JD, Scott Fraser, PhD, Carmen Puliafito, MD, MBA (Photo courtesy of Children's Hospital Los Angeles)

USC and Children’s Hospital Los Angeles launch imaging lab for translational research

With the launch of the Translational Biomedical Imaging Lab (TBIL), investigators at the University of Southern California (USC) and The Saban Research Institute of Children’s Hospital Los Angeles moved us closer to a …

Andy McMahon (Photo by Phil Channing)

Hedgehog’s long snout finds a cure

In 1993, the Human Frontier Science Program (HFSP) funded three researchers through one of the program’s prestigious Research Grants to work jointly on patterning of the mid-hindbrain region of the vertebrate embryo. …

Mouse femur with enchondroma-like structure (Image by Lick Lai)

USC study reveals a protein that keeps people—and their skeletons—organized

Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research from …

The study focused on tumors that can cause progressive enlargement of the jaw.

Healthy stem cells can create benign tumors in jaw

A new study from the Ostrow School of Dentistry of USC published in Cell Stem Cell illustrates how changes in cell signaling can cause ordinary stem cells in the jaw to start …

Staining of slow-cycling sweat gland cells (green) with the protein laminin (red) and the fluorescent stain DAPI (blue) (Image by Yvonne Leung)

USC researcher learns how to break a sweat

Without sweat, we would overheat and die. In a recent paper in the journal Public Library of Science One (PLOS ONE), USC faculty member Krzysztof Kobielak and a team of researchers explored …

Embryonic stem cells (Image/courtesy of Qi-Long Ying)

USC researcher reveals how to better master stem cells’ fate

USC scientist Qi-Long Ying and a team of researchers have long been searching for biotech’s version of the fountain of youth — ways to encourage embryonic stem cells (ESCs) and epiblast stem …

Yang Chai (Photo courtesy of the Ostrow School of Dentistry of USC)

Ostrow School study links growth factor glitch to tongue defects

New findings about how cell signaling directs tongue development may have big clinical applications for healing tongue defects, according to an Ostrow School of Dentistry of USC study published in The Journal …

Compared with a normal zebrafish (top), this mutant (bottom) is a real bone head. (Image by Sandeep Paul and Seth Ruffins)

Winner of the August 2013 USC Stem Cell Image of the Month Contest

Dr. Andrew McMahon and the judges of the USC Stem Cell Image of the Month contest would like to congratulate our August 2013 winners, Dr. Seth Ruffins and Sandeep Paul, a postdoc …

From left, Andrew P. McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, with Yong Chen’s son Gary and researcher Qi-Long Ying (Photo by Cristy Lytal)

Businessman invests in stem cell research at USC

Chinese businessman Yong Chen has pledged $1 million to USC stem cell researcher Qi-Long Ying to support his future “eureka moments.” “When I talked to Mr. Chen, I told him that groundbreaking …

Neural stem cells derived from self-renewing mouse embryonic stem cells (Image courtesy of Qi-Long Ying)

A special protein helps embryonic stem cells keep their options open

In the ongoing quest to understand how embryonic stem cells (ESCs) retain their ability to differentiate into virtually any kind of cell, USC faculty member Qi-Long Ying and a team of researchers …

From left, Gage Crump, Jay R. Lieberman and Francesca Mariani (Photo by Cristy Lytal)

USC announces winners of first Regenerative Medicine Initiative awards

Three newly assembled disease teams within USC Stem Cell will take the early steps this year that might lead to future stem-cell based therapies for certain forms of deafness, bone defects and …

Songtao Shi, DDS, PhD (Photo courtesy of the Ostrow School of Dentistry of USC)

Stem cells found in gum tissue can fight inflammatory disease

Stem cells found in mouth tissue can not only become other types of cells but can also relieve inflammatory disease, according to a new Ostrow School of Dentistry of USC study in …

Wange Lu (Photo by Chris Shinn)

USC study sheds light on stem cell reprogramming

Researchers are learning how to turn regular cells into stem cells, a process called reprogramming. However, some of the mechanisms of the process remain unknown, such as why only a small proportion of the cells can be reprogrammed. Researchers have at least part of the answer: the structure of genes.

Norman Arnheim

Common genetic disease linked to father’s age

Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan syndrome are so common—a mutation, which causes the disease, disproportionately increases a normal father’s production of …