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Impromptu McMahon lab meeting; featured image for USC Stem Cell: An incubator for medicine of the 21st century

USC Stem Cell: An incubator for medicine of the 21st century

Just over a decade ago, USC was a university with a few scattered stem cell biologists, and a vision for total transformation. The university was committed to designing a unique “incubator” for …

Illustration by Jonathan Haase; featured image for Cycles of a fasting-mimicking diet help mice live longer, healthier

Cycles of a fasting-mimicking diet help mice live longer, healthier

While many diets have been studied for effectiveness in preventing obesity and heart disease in both mice and humans, research on the effects and benefits of short, periodic cycles of fasting on obesity and heart health are lacking. In a new USC study on the health effects of a low-calorie diet that mimics …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology); featured image for Bérénice Benayoun receives prestigious investigator-focused grant

Bérénice Benayoun receives prestigious investigator-focused grant

The Maximizing Investigators’ Research Award directly supports scientists, providing stability, flexibility and more opportunities for breakthroughs. The National Institute of General Medical Sciences has awarded an R35 Maximizing Investigators’ Research Award (MIRA) …

(Image courtesy of iStock); featured image for Top scientists and research institutions propose improvements to cell- and gene-based therapy development

Top scientists and research institutions propose improvements to cell- and gene-based therapy development

Led by a USC cell and gene therapy researcher, an international coalition calls for more transparency and reproducibility in research and development of breakthrough treatments.   Scientists around the world are achieving significant …

Scott Fraser by Noe Montes; featured image for USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser is known for inventing new microscopes and other tools to observe living, developing embryos. But one of his lab’s most important pieces of technology filters coffee instead …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology); featured image for Bérénice Benayoun receives GSA Nathan Shock New Investigator Award

Bérénice Benayoun receives GSA Nathan Shock New Investigator Award

The Gerontological Society of America (GSA)—the nation’s largest interdisciplinary organization devoted to the field of aging—has chosen Assistant Professor Bérénice Benayoun of the USC Leonard Davis School of Gerontology as the 2021 …

Unmesh Jadhav and Kimberly Gokoffski; featured image for The Baxter Foundation advances USC research on optic nerve disease and colorectal cancer

The Baxter Foundation advances USC research on optic nerve disease and colorectal cancer

For over 60 years, the Donald E. and Delia B. Baxter Foundation has supported innovative biomedical research at the Keck School of Medicine of USC, each year granting $100,000 awards to two …

(Image courtesy of Children's Hospital Los Angeles)

Spike in severe pediatric type 2 diabetes complication during COVID-19 pandemic

Children’s Hospital Los Angeles study uncovers life-threatening trend in children. According to the Centers for Disease Control and Prevention (CDC), children generally appear to be less severely impacted by COVID-19 than adults. …

Leonardo Morsut; featured image for USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development

USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development

Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment. To begin …

In the cGMP facility space before construction. From left: Mohamed Abou-el-Enein; Tom Buchanan; Alan S. Wayne; Caryn Lerman; and Nikos Carli. (Photo/Sergio Bianco); featured image for CHLA, Keck School, Keck Medicine and USC Norris partner on cell therapy program as construction on new facility begins

CHLA, Keck School, Keck Medicine and USC Norris partner on cell therapy program as construction on new facility begins

The essence of translational medicine is taking an idea from the drawing board and “translating” it into a real-world treatment that helps patients. The winding road of that process takes plenty of …

Xi Chen; featured image for For USC scientist Xi Chen, a chicken is more than just an egg’s way of making another egg

For USC scientist Xi Chen, a chicken is more than just an egg’s way of making another egg

USC postdoctoral researcher Xi Chen knows that you have to break a few eggs in order to grow chicken stem cells. His work on maintaining embryonic stem cells (ESC) from chicken eggs …

Osteoblasts; featured image for Broad Clinical Fellows take a stem cell-based approach to liver disease and bone loss

Broad Clinical Fellows take a stem cell-based approach to liver disease and bone loss

This year’s Broad Clinical Research Fellows are developing stem cell-based approaches for patients of all ages—from two-week-old infants with liver disease, to senior citizens with bone loss following joint replacement surgeries. Since …

Senta Georgia in the lab; featured image for Can COVID-19 cause diabetes?

Can COVID-19 cause diabetes?

Can the novel coronavirus—SARS-CoV-2—cause diabetes? No one knows, but Senta Georgia, PhD, is trying to find out. Dr. Georgia, an investigator in The Saban Research Institute of Children’s Hospital Los Angeles, recently …

liver image; featured image for A high-tech look at rejection in pediatric liver transplants

A high-tech look at rejection in pediatric liver transplants

Surgeon-scientist Juliet Emamaullee, MD, PhD, spends much of her time seeing patients and performing pediatric liver transplants at Children’s Hospital Los Angeles. But you’ll also find her in the lab—studying how to …

Tracy Grikscheit; featured image for USC pediatric surgeon aims to heal infants using stem cells

USC pediatric surgeon aims to heal infants using stem cells

Tracy Grikscheit helps babies with digestive disorders. Stem cells could help her develop life-changing treatments. It’s an instinct many surgeons have: Whatever you have to remove, replace it with something better. Something …

D. Brent Polk; featured image for Treatment for Inflammatory bowel disease doesn’t always work; new study uncovers why

Treatment for Inflammatory bowel disease doesn’t always work; new study uncovers why

Inflammatory bowel disease (IBD) affects more than 70,000 children in the United States and the prevalence is rising. In fact, 25% of the 3.1 million individuals with IBD present before 21 years …

Fraser by Noe Montes; featured image for USC biological imaging innovator elected to National Academy of Medicine

USC biological imaging innovator elected to National Academy of Medicine

Scott Fraser, Provost Professor of Biological Sciences, Biomedical Engineering, Physiology and Biophysics, Stem Cell Biology and Regenerative Medicine, Pediatrics, Radiology and Ophthalmology, has been elected to the National Academy of Medicine. Fraser, …

USC's stem cell research center

California’s biggest stem cell experiment: The impact of the stem cell ballot proposition at USC

In 2008, USC broke ground on an $80 million building dedicated solely to stem cell research and regenerative medicine. The plans called for a monolithic structure clad in black marble and reflective …

Scott E. Fraser; featured image for USC’s Scott E. Fraser elected to National Academy of Medicine

USC’s Scott E. Fraser elected to National Academy of Medicine

USC biophysicist Scott E. Fraser, PhD, has as been elected to the National Academy of Medicine, the organization announced Monday. He’s among 100 new members of the Academy. “For integrating biophysics, quantitative …

diabetes; featured image for Treating type 2 diabetes in youth

Treating type 2 diabetes in youth

The occurrence of Type 2 diabetes in youth is increasing, yet the ability to control the disease by regulating blood glucose levels has proven difficult for this age group. A study published …