Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, the replacement structure is an imperfect cartilage tube. Now, for the first time, a study in Nature Communications describes how stem cells can help lizards regenerate better tails. Learn more from the study’s corresponding author, Thomas Lozito, an assistant professor of orthopaedic surgery and stem cell biology and regenerative medicine at the Keck School of Medicine of USC. (Video by Sergio Bianco)