Dr. McMahon’s laboratory explores the mechanisms that maintain stem/progenitor cells and regulate their differentiation to mature cell types of different organ systems, particularly the kidney. By combining genetic and genomic approaches with high resolution imaging, his group is aiming to obtain a deeper understanding of stem cell biology and to develop novel therapeutic strategies for regenerative medicine.
Stories
Halloween retreat showcases USC’s “scary smart” stem cell researchers
It was no tricks and all treats at the seventh annual retreat for the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, held at the university’s …
General David H. Petraeus gets a four-star tour of HSC
Petraeus—who also serves as the Judge Widney Professor at USC and Chairman of the KKR Global Institute—started his morning with a glimpse into the human brain. Faculty and students from the USC …
USC stem cell researcher Lori O’Brien receives the first Broad Fellowship
What makes stem cells develop into kidneys? Lori O’Brien, a postdoctoral research associate in the laboratory of Andy McMahon, has received the first Broad Fellowship to help answer this question. O’Brien is …
USC rolls out the cardinal carpet on Stem Cell Awareness Day
When asked why stem cell research matters, guests at this year’s Stem Cell Awareness Day gave many creative answers. “Because it has unlimited potential to treat human diseases.” “Because every part of …
USC welcomes its inaugural class of stem cell master’s students
USC welcomed its inaugural class of master’s students in stem cell biology and regenerative medicine to one of the first programs of its kind in the United States. To celebrate the launch …
USC stem cell PhD students present their blueprints for rebuilding the body
Video by Alric Devotta The students in the new PhD program in Development, Stem Cells, and Regenerative Medicine recently presented some ideas that would give Dr. Frankenstein a run for his money. …
USC, UCLA and UCSF put their heads together to find stem cell-based cures for craniofacial defects
One in every 2,000 babies is born with a skull that can’t grow normally. Various sections of these babies’ skulls are fused together at joints called sutures, constricting the developing brain and …
USC Stem Cell scientists lay a TRAP for disease
USC Stem Cell scientists have set a “mouse TRAP” to capture the early signs of kidney failure, as described by a recent study published in the Journal of Clinical Investigation. Their new …
USC Stem Cell and the USC Norris Comprehensive Cancer Center accelerate drug discovery
Three teams of USC stem cell researchers have won a coveted prize — the opportunity to test 3,000 drug candidates or chemicals for the potential to help patients. Two teams will focus …
Andy McMahon and USC Stem Cell: From discoveries to cures
Video by Little Pictures How do fingers become fingers and not toes? How does the brain generate the correct number of neurons? How do the kidneys branch into the complex and elegant …
USC Stem Cell celebrates the grand opening of the Choi Family Therapeutic Screening Facility
How can scientists make more accurate predictions about which potential drugs will effectively treat disease — before launching expensive and laborious human clinical trials? USC’s new Choi Family Therapeutic Screening Facility offers …
USC launches one of California’s first master’s programs in stem cell biology and regenerative medicine
Video by Ryan Ball USC is pleased to offer one of the first master’s programs in stem cell biology and regenerative medicine in California. “The program gives students a unique entrée into …
USC Roski and USC Stem Cell announce new collaboration
What happens when USC students — some studying art and design, others stem cell biology — examine zebrafish skulls under a microscope? It depends on who’s looking. During spring 2014, scientists at the …
Min Yu and Rong Lu explore how one bad cell spoils the bunch
Principal investigators Min Yu, MD, PhD, and Rong Lu, PhD, had plans to collaborate long before they were both recruited to the Department of Stem Cell Biology and Regenerative Medicine at the …
Stem cells prove their potency at CHLA annual symposium
The Saban Research Institute of Children’s Hospital Los Angeles Annual Symposium, held on Feb. 21, focused on the promise of regenerative medicine and cellular therapies — from curing HIV to building organs …
USC and Children’s Hospital Los Angeles launch imaging lab for translational research
With the launch of the Translational Biomedical Imaging Lab (TBIL), investigators at the University of Southern California (USC) and The Saban Research Institute of Children’s Hospital Los Angeles moved us closer to a …
Hedgehog’s long snout finds a cure
In 1993, the Human Frontier Science Program (HFSP) funded three researchers through one of the program’s prestigious Research Grants to work jointly on patterning of the mid-hindbrain region of the vertebrate embryo. …
Winner of the October 2013 USC Stem Cell Image of the Month Contest
Dr. Andrew McMahon, Dr. Seth Ruffins and the judges of the USC Stem Cell Image of the Month contest would like to congratulate our October 2013 winner, Sanjeev Kumar, a postdoctoral research …
USC study reveals a protein that keeps people—and their skeletons—organized
Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research from …
A Retreat from everything but stem cells
It wasn’t the pristine 27-hole course that drew more than 120 stem cell researchers from USC and beyond to the Desert Princess Golf Resort near Palm Springs. It was the sixth annual …