Three USC researchers win $4.3 million in awards from California’s stem cell agency

Three scientists from Keck Medicine of USC have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine (CIRM) for research that includes creating a temporary liver for patients, finding novel ways to treat immune disorders and blood diseases, and developing new animal models for heart failure, diabetes and neurodegenerative diseases. The grants, …

Aswathy Ammothumkandy and her family

USC Stem Cell postdoc Aswathy Ammothumkandy recognized by the American Epilepsy Society for her work with neural stem cells

USC Stem Cell postdoctoral trainee Aswathy Ammothumkandy vividly recalls when the tour guide shared the story of Dolly the cloned sheep during her ninth-grade field trip to the regional science center in her home town of Kozhikode, India. From that moment on, Ammothumkandy set her heart on a career in biotechnology. “I thought that this …


How does air pollution influence Alzheimer’s risk?

Higher exposure to air pollution is strongly associated with cognitive impairment and Alzheimer’s disease, especially for people with certain genetic risk factors for the disease. Exactly how pollution interacts with these genes to increase dementia risk is still unknown, but clues may be found in how stem cells within the brain undergo aging, according to …

Neural stem cells

Do our brains age faster than the rest of our bodies?

If you feel your brain power diminishing as you advance into middle age and beyond, blame your neural stem cells. In a new study published in Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi demonstrates that neural stem cells—the stem cells of the nervous system—age rapidly. “There is chronological aging, …

JO neurons

USC Stem Cell scientists start a buzz around fruit flies in hearing research

Even though a fruit fly doesn’t have ears, it can hear with its antennae. In a new study published in the journal Development, USC Stem Cell scientists describe how adult flies can regenerate sensory hearing cells in their antennae, and how studying flies can provide a new way to understand and develop treatments for the …

Long Cai

The Broad Foundation brings together stem cell scientists, engineers and physicians at USC and beyond

Developing new stem cell therapies requires more than a solo biologist having a eureka moment alone in the lab. Real progress relies on collaborations between biologists, engineers and physicians. That’s why The Eli and Edythe Broad Foundation has continued its support of two strategic initiatives: innovation awards bringing together teams of engineers and scientists from …

USC brings the world’s largest stem cell conference to Los Angeles

For the first time ever, the City of Los Angeles hosted the world’s largest stem cell conference. By choosing Los Angeles as the host city for this major annual meeting, the International Society for Stem Cell Research (ISSCR) acknowledged the city’s growing importance as a hub for the biosciences, as well as the world-class research …

USC Stem Cell junior faculty balance babies with biomedical research

Growing stem cells isn’t just something junior faculty do in the lab. Eight of the junior faculty in the Department of Stem Cell Biology and Regenerative Medicine recently welcomed new babies into their families—more than half of them within the past year. Here, our junior faculty parents share their joy and wisdom about balancing career …

USC Stem Cell and BCRegMed Virtual Symposium brings Canada to California

It didn’t require plane tickets to bring together scientists from USC Stem Cell in Los Angeles and BCRegMed in Vancouver. During October’s Virtual Symposium, videoconferencing technology enabled these scientists to share ideas as if they were sitting in the same conference room—even though they were more than 1,200 miles apart.

At the retreat for USC’s stem cell department, the students become the masters

Students and trainees took center stage at the annual retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. They presented their latest research to the 180 stem cell scientists who gathered at the event, held at the Pala Mesa Resort in Fallbrook, California this September.

The Baxter Foundation awards grants to USC researchers Michael Bonaguidi and Sanda Win

From the brain to the bile, the Donald E. and Delia B. Baxter Foundation is supporting innovative medical research by granting $100,000 awards to two assistant professors: Michael Bonaguidi in the Department of Stem Cell Biology and Regenerative Medicine; and Sanda Win in the Department of Medicine’s GI/Liver Division.

Scientists get into detail at the retreat for USC’s stem cell department

“The process of disease is about detail,” said Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. Held on October 20 and 21 at the Pala Mesa Resort in Fallbrook, California, the …

Whittier Foundation backs new group of research projects

The L.K. Whittier Foundation has been a critical source of funding for cancer research at the Keck School of Medicine of USC and the USC Norris Comprehensive Cancer Center, supporting clinicians and basic scientists who are advancing tailored therapies and nanobiotechnology.

USC’s stem cell scientists secure the dollars to fight disease

The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous grants to support stem cell-based approaches to study and treat illnesses ranging from osteoarthritis to Alzheimer’s disease to cystic fibrosis. Here are a …

Meet PhD student Albina Ibrayeva, presenter at the ISSCR 2017 Annual Meeting

What happens to the stem cells in our brains as we age? Albina Ibrayeva, a PhD student in the USC Stem Cell laboratory of Michael Bonaguidi, will address this question in a presentation at the prestigious International Society for Stem Cell Research (ISSCR) Annual Meeting in Boston in June 2017. We recently caught up with …

Next generation of stem cell scientists detail their research from head to toe

The Stem Cell and Developmental Biology Retreat was a total body experience — covering organ systems ranging from the brain to the skeleton, from the kidney to the heart. Held on May 20 in USC’s Galen Center, the retreat showcased presentations and research posters by dozens of postdoctoral scholars and PhD students.

Ismael Fernández-Hernández receives USC-CONACYT Provost Fellowship

We can learn a lot from fly brains, according to Ismael Fernández-Hernández, a postdoctoral fellow in the USC Stem Cell laboratory of Michael Bonaguidi. Fernández-Hernández is an accomplished researcher who showed that adult fruit flies have the potential for replenishing brain cells lost to disease, injury or aging. He is also one of 11 new …

USC Stem Cell researcher Michael Bonaguidi dissects the film Self/Less

Can science make us immortal? At a recent Los Angeles screening of director Tarsem Singh’s science fiction thriller Self/Less, USC Stem Cell researcher Michael Bonaguidi and University of Arizona researcher Wolfgang Fink tackled this and other big questions during a panel discussion moderated by KIIS-FM DJ Manny Guevara, known as “Manny on the Streetz.”

Tri-institutional Stem Cell Retreat brings together Broad centers from USC, UCLA and UCSF

Working alone, a scientist or university can only make so much progress in finding answers to basic questions or new treatments for diseases ranging from HIV to cancer to diabetes. That’s why nearly 300 scientists from USC, UCLA and UCSF gathered in Santa Barbara for a Tri-institutional Stem Cell Retreat. Hosted by USC at the …

USC Stem Cell Symposium creates scientific synergy

Provost Michael Quick convened the inaugural USC Stem Cell Symposium with a straightforward truth about the future of regenerative medicine: “it will take a dedicated community of scholars across the disciplines to have maximum impact.” The January 16 symposium brought together precisely such a community, with speakers hailing from USC’s schools of medicine, dentistry, gerontology …

Michael Bonaguidi contributes brain power to stem cell research at USC

Video by Alric Devotta As a child, Michael Bonaguidi dreamed of shaping cities as an architect or engineer. Now, he dreams of shaping brains as the newest principal investigator to join USC’s Department of Stem Cell Biology and Regenerative Medicine.

Michael Bonaguidi, PhD

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