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Three USC researchers win $4.3 million in awards from California’s stem cell agency

Three scientists from Keck Medicine of USC have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine (CIRM) for research that includes creating a temporary liver for patients, finding novel ways to treat immune disorders and blood diseases, and developing new animal models for heart failure, diabetes and neurodegenerative diseases. The grants, …

California’s biggest stem cell experiment: The impact of the stem cell ballot proposition at USC

In 2008, USC broke ground on an $80 million building dedicated solely to stem cell research and regenerative medicine. The plans called for a monolithic structure clad in black marble and reflective glass, rising five stories and enclosing nearly 90,000 square feet. When it was completed, the university had a stunning new contemporary research space …

Paula Cannon

Gene therapy research for HIV awarded $14.6 million NIH grant

An HIV research program led by scientists at USC and the Fred Hutchinson Cancer Research Center has received a five-year, $14.6 million grant from the National Institutes of Health. The team is advancing a gene therapy approach to control the virus without the need for daily medicines. The program’s co-directors are Paula Cannon, PhD, Distinguished Professor …

Kalya Stanten

Countdown to Commencement: USC Stem Cell master’s student Kalya Stanten follows the science

By following her love of science, USC master’s student Kalya Stanten has found herself in some very interesting places—including a virology lab at the outset of the COVID-19 pandemic. “I’m in Paula Cannon’s lab,” said Stanten, who is graduating with a Master of Science in Stem Cell Biology and Regenerative Medicine. “Through my own work …

USC researchers converge at the Interdisciplinary Stem Cell Symposium

“The field of stem cell biology is one of our great convergence opportunities,” said USC Provost Michael Quick, addressing an audience of biologists, chemists, physicists, engineers, clinicians and many others. This diverse group came together for the Interdisciplinary Stem Cell Symposium, hosted by USC Stem Cell and the USC Medicine, Engineering, Science and Humanities (MESH) …

At the retreat for USC’s stem cell department, the students become the masters

Students and trainees took center stage at the annual retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. They presented their latest research to the 180 stem cell scientists who gathered at the event, held at the Pala Mesa Resort in Fallbrook, California this September.

Scientists get into detail at the retreat for USC’s stem cell department

“The process of disease is about detail,” said Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. Held on October 20 and 21 at the Pala Mesa Resort in Fallbrook, California, the …

USC’s stem cell scientists secure the dollars to fight disease

The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous grants to support stem cell-based approaches to study and treat illnesses ranging from osteoarthritis to Alzheimer’s disease to cystic fibrosis. Here are a …

USC Stem Cell scientists enter the conversation about CRISPR

CRISPR-Cas9 is a gene-editing technique that enables scientists to disable, replace or modify sections of DNA. It allows for unprecedented precision and speed in the field of genome editing. It has been used to create micropigs to be sold as pets and to try to eradicate HIV infection in humans. The scientific community is concerned about altering human embryos to …

Americans for Cures animations highlight stem cell clinical trials

How do clinical trials work? With the support of Proposition 71 and the California Institute for Regenerative Medicine (CIRM), California stem cell scientists at USC and elsewhere are developing a new generation of cellular therapies, which will come with unique challenges — and, hopefully, benefits — that differ from traditional drug-based medicine.

USC announces winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards

Two collaborative teams within USC Stem Cell are developing new approaches that could eventually help patients with heart disease, frontotemporal dementia and amyotrophic lateral sclerosis (ALS). The teams are the winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards, supported by a generous bequest by the Audrey E. Streedain Trust to the Department of …

USC and Sangamo researchers advance genome editing of blood stem cells

Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences. In an upcoming study in Nature Biotechnology, co-first authors Colin M. Exline from USC and Jianbin Wang from Sangamo BioSciences describe a new, more efficient way to edit genes in blood-forming or “hematopoietic” stem …

The road to a cure for HIV/AIDS

Something wonderful sometimes happens when scientists and the public get together to talk about research. All the jargon, all the technical language falls away, and it becomes instead a conversation between the two groups with most at stake: the people in need of a treatment or cure, and the people trying to develop it. Last …

Tri-institutional Stem Cell Retreat brings together Broad centers from USC, UCLA and UCSF

Working alone, a scientist or university can only make so much progress in finding answers to basic questions or new treatments for diseases ranging from HIV to cancer to diabetes. That’s why nearly 300 scientists from USC, UCLA and UCSF gathered in Santa Barbara for a Tri-institutional Stem Cell Retreat. Hosted by USC at the …

CIRM-funded clinical trial aimed at blocking HIV/AIDS in people gets the go ahead

An innovative therapy using a patient’s own stem cells, modified to resist infection with the AIDS virus, has been given approval by the Food and Drug Administration (FDA) to begin a clinical trial in people. CIRM, California’s stem cell agency, is funding that trial.

“Million-dollar ideas” seminar

At a special seminar on February 24, USC Stem Cell Principal Investigators discussed their “million-dollar ideas” for creating new tools and technologies to usher in the era of regenerative medicine. They shared research plans for their new, three-year Tools and Technologies grants from the California Institute for Regenerative Medicine (CIRM).

USC Stem Cell Symposium creates scientific synergy

Provost Michael Quick convened the inaugural USC Stem Cell Symposium with a straightforward truth about the future of regenerative medicine: “it will take a dedicated community of scholars across the disciplines to have maximum impact.” The January 16 symposium brought together precisely such a community, with speakers hailing from USC’s schools of medicine, dentistry, gerontology …

USC hosts California stem cell agency’s tenth birthday bash

Few 10 year olds have brought 10 potential medical treatments into clinical trials. The California Institute for Regenerative Medicine (CIRM), however, is a truly exceptional 10 year old. In 2004, the people of California created CIRM to dispense $3 billion in voter-approved dollars to fund stem cell research in the state. Progress has been impressive. …

USC Stem Cell researchers share a vision of the future at the Milken Institute Global Conference

What do former British Prime Minister Tony Blair and singer Will.i.am have in common? They both attended this year’s Milken Institute Global Conference, where USC Stem Cell researchers offered an exciting glimpse into the future of regenerative medicine.

Stem cells prove their potency at CHLA annual symposium

The Saban Research Institute of Children’s Hospital Los Angeles Annual Symposium, held on Feb. 21, focused on the promise of regenerative medicine and cellular therapies — from curing HIV to building organs such as kidneys and intestines. The panel of speakers included investigators from Children’s Hospital Los Angeles, USC, Children’s Hospital of Philadelphia, the University …

Paula Cannon, PhD

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