Menu

Stories

Nelson Poliran, Jr.

Where are they now? Stem cell master’s program alumnus Nelson Poliran, Jr., a dentist in rural New Mexico

In this series of alumni profiles, we highlight graduates of USC’s master of science program in stem cell biology and regenerative medicine. Our accomplished alumni have pursued many different paths—ranging from a …

Image courtesy of the Ostrow School of Dentistry of USC

USC collaboration helps FaceBase reach 1,000-dataset milestone

The data repository allows craniofacial scientists to share data, which could ultimately lead to improved care for patients with craniofacial developmental disorders. Rapid technological development in the past decade has allowed scientists …

Scott Fraser by Noe Montes

USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser is known for inventing new microscopes and other tools to observe living, developing embryos. But one of his lab’s most important pieces of technology filters coffee instead …

Broken eggs

USC researchers regenerate skull tissue using stem cells and 3-D printed scaffolding in swine

Every year, surgeons perform more than 5,000 cranioplasties—surgeries that restore cranial defects—on patients who have experienced critical size cranial defects resulting from congenital defects, head trauma or tumor removals. Traditional materials used …

Image courtesy of the Ostrow School of Dentistry of USC

A quantum leap

Ostrow jumps to fourth top-funded U.S. dental institution by the National Institute of Dental and Craniofacial Research. If a global pandemic was meant to slow researchers down in their quest for knowledge, …

Robert E. Maxson

USC celebrates Robert E. Maxson’s lifetime of achievement and adventure

USC Emeritus Professor Robert E. Maxson has an understated explanation for why he’s flown so many planes, sailed so many boats, skied so many mountains, played so many guitars, taken so many …

Is this the gamechanger we’ve been waiting for in craniosynostosis?

One of our every 2,500 infants born in the United States will suffer from craniosynostosis — a craniofacial defect caused by the premature fusion of the different bones that comprise the human …

Conventional treatment for craniosynostosis often involves surgery and cranial helmets during the long recovery process. (Photo courtesy of iStock)

Stem cells may correct deformity and restore brain function after childhood disorder

USC scientists have regenerated parts of the skull affected by a common birth defect called craniosynostosis. Using stem cells to regenerate parts of the skull, USC scientists partially corrected a skull deformity …

USC's stem cell research center

California’s biggest stem cell experiment: The impact of the stem cell ballot proposition at USC

In 2008, USC broke ground on an $80 million building dedicated solely to stem cell research and regenerative medicine. The plans called for a monolithic structure clad in black marble and reflective …

Skull (Image courtesy of Yang Chai)

USC-led research team shares 10 years’ progress in collecting data to push craniofacial science forward

It has been a little more than a decade since the National Institute of Dental and Craniofacial Research (NIDCR) launched FaceBase, a central repository for craniofacial datasets and tools meant to advance …

Microscope (Photo courtesy of the Ostrow School of Dentistry of USC)

Investigating the neighboring environment for stem cells

A long-held goal in dental research is to harness the power of stem cells to regenerate bone and dental tissue. But to do so, it’s important to fully understand the environment the …

Yang Chai

Yang Chai appointed University Professor

Associate Dean of Research Yang Chai PhD ’91, DDS ’96 has been appointed a University Professor, making history as the first faculty member to achieve such distinction at the Ostrow School of …

C-DOCTOR

Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration awarded $30-million grant

The studies seem like something straight out of science fiction. There’s one focused on using stem cells to regenerate skull bone for patients with skull defects. Another aims to develop a hydrogel …

USC researcher Yang Chai has received another five-year grant to bolster his research into the causes of one of the most common congenital birth defects.

Cleft palate research continues to help patients

Associate Dean of Research Yang Chai PhD ’91, DDS ’96 has been awarded a five-year, nearly $2 million grant by the National Institute of Dental and Craniofacial Research (NIDCR) for research focused …

Craniofacial conditions, or malformation of the head and face, affect approximately 600,000 people in the United States, according to Children’s National Health System. (Photos courtesy of iStock)

USC researchers receive $12.5 million grant for craniofacial research data-sharing endeavor

Nearly half of all birth defects involve the face and skull and, for the most part, scientists remain unclear as to why most occur. To better serve families at risk for these …

The discovery could change the way dental implants are placed, allowing dentists to regenerate tooth roots that better integrate with jaw bone structures.

Ostrow researchers discover how genes for tooth roots turn on and off

To figure out how the body changes over time, researchers are increasingly looking to understand epigenetics, the study of changes in organisms caused by modification of gene expression rather than alteration of …

Yang Chai (Photo by Chris Shinn)

Yang Chai bridges the gap from the lab bench to the dental chair

As a young oral surgeon in China, Yang Chai often operated on babies born with cleft lips or palates. “You talk to the parents, and they were very emotional and trying find …

How the roots of teeth develop has long been a mystery. Professor Yang Chai aims to change that — and eventually regrow the roots of teeth.

Researchers seek the root of tooth development

The lower two-thirds of a tooth are known as the root. Normally covered in bone, they anchor the tooth into the jaw. But the exact mechanisms and pathways that create the root …

Children with craniosynostosis could one day be treated with a biological intervention.

USC researchers draw closer to biological treatment for birth defect

Could we be one step closer to developing a biological treatment for craniosynostosis? Building upon a body of research that demonstrated that the premature fusion of skull bones — which can cause …

The Interdisciplinary Stem Cell Symposium sparked collaborations. (Photo by Sergio Bianco)

USC researchers converge at the Interdisciplinary Stem Cell Symposium

“The field of stem cell biology is one of our great convergence opportunities,” said USC Provost Michael Quick, addressing an audience of biologists, chemists, physicists, engineers, clinicians and many others. This diverse …

Yang Chai, DDS, PhD