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Three USC researchers win $4.3 million in awards from California’s stem cell agency

Three scientists from Keck Medicine of USC have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine (CIRM) for research that includes creating a temporary liver for patients, finding novel ways to treat immune disorders and blood diseases, and developing new animal models for heart failure, diabetes and neurodegenerative diseases. The grants, …

SARS-CoV-2

USC Stem Cell scientists use “mini-lungs” and lung models to understand COVID-19

USC scientists are testing out experimental COVID-19 treatments on human “mini-lungs” and lung models, grown in the laboratory using stem cells. With names such as organoids and lung-chips, these simplified, lung-like structures are critically useful for studying infection and for screening large numbers of drug-like molecules to identify promising leads. Ya-Wen Chen—a new assistant professor …

McMahon

A Message from Director and Chair Andy McMahon

I hope that this message finds you safe and well. As we return to our labs, I thought this would be a good time to let you know about what has been happening in USC’s stem cell research center. In March, we received instructions to wind down non-COVID-19 research projects in our labs, to minimize …

Qi-Long Ying

Shanghai Cell Therapy Group launches collaboration with USC researcher to improve the ex vivo expansion of hematopoietic stem cells for clinical applications

Shanghai Cell Therapy Group (SHCell) recently entered into a six-year research collaborative project with Professor Qi-Long Ying from the University of Southern California (USC). Through the project, sponsored by $3.6 million from the Baize Plan Fund, the Ying laboratory aims to develop conditions for the long-term ex vivo expansion of mouse and human hematopoietic stem …

Andrew P. McMahon

USC Professor Andrew P. McMahon elected to the National Academy of Sciences

Andrew P. McMahon—who is the W.M. Keck Provost and University Professor in USC’s departments of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine, and Biological Sciences at the Dornsife College of Letters, Arts and Sciences—has been elected as a new member of the National Academy of Sciences in honor of his …

Long Cai

The Broad Foundation brings together stem cell scientists, engineers and physicians at USC and beyond

Developing new stem cell therapies requires more than a solo biologist having a eureka moment alone in the lab. Real progress relies on collaborations between biologists, engineers and physicians. That’s why The Eli and Edythe Broad Foundation has continued its support of two strategic initiatives: innovation awards bringing together teams of engineers and scientists from …

USC finds new routes to industry engagement and funding

Story courtesy of In-Part Over the last year, Dr. Qing Liu-Michael, Program Director at USC Stem Cell and the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at the University of Southern California (USC), has been using IN-PART’s Discover service to find new streams of collaboration with companies proactively seeking academic …

Stem cell scientists reveal key differences in male, female kidney

USC researchers have completed a detailed deconstruction of the kidney, revealing for the first time an intimate portrait of sexual differences and more in the organ. The findings could benefit 37 million Americans suffering from kidney disease by helping to distinguish how it affects men and women differently. They can help doctors pinpoint genes linked …

USC brings the world’s largest stem cell conference to Los Angeles

For the first time ever, the City of Los Angeles hosted the world’s largest stem cell conference. By choosing Los Angeles as the host city for this major annual meeting, the International Society for Stem Cell Research (ISSCR) acknowledged the city’s growing importance as a hub for the biosciences, as well as the world-class research …

Jean Rosenbaum

France-USA Stem Cell Symposium gathers la crème de la crème

Science was the common language at the first France-USA Stem Cell Symposium, held at the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC. The event brought together over 100 stem cell scientists from France and the United States on the eve of the field’s largest annual conference—the International …

$10 million gift from Broad Foundation advances USC stem cell research on aging-associated disease

USC’s groundbreaking stem cell research and training programs have received a major boost thanks to a $10 million gift from the Eli and Edythe Broad Foundation. The donation is part of the foundation’s latest $30 million funding initiative to support its namesake Eli and Edythe Broad stem cell research centers at USC, UCLA and University …

From restoring sight to reversing brain damage, USC stem cell researchers are making life-changing discoveries

If anyone has a clear vision of the power of stem cell cures, it’s Anna Kuehl. She suffered a retina-wrecking disease that cost her much of her sight before USC physicians surgically implanted stem cells to restore her ability to see. Today, she can see the letters on computer keys, use her iPhone and read …

RSVP for 6/26 USC Public Symposium on a stem cell-based approach to treating age-related blindness

A Public Symposium co-sponsored by USC Stem Cell and the Choi Family @ISSCCR 2019 RSVP at https://www.eventbrite.com/e/bringing-stem-cells-to-patients-treating-age-related-blindness-tickets-62892259441#tickets PROGRAM *Spanish translation available. 6:30 p.m. Registration and free food 7–8 p.m. Andrew P. McMahon, USC: Welcome Remarks Kevin McCormack, CIRM: The Role of CIRM and Public Support for Stem Cell Research Mark S. Humayun, USC: Age-related Macular …

Stem cell scientists take it one cell at a time at the Junior Faculty Candidate Mini-symposium

Cells should be treated as individuals, according to the scientists who presented research at the Junior Faculty Candidate Mini-symposium, hosted by USC’s Department of Stem Cell Biology and Regenerative Medicine on February 5. While cells have traditionally been evaluated as populations, these up-and-coming scientists shared their frontier approaches for studying the specific features and activities …

McMahon named University Professor; Davies, Matarić and Pastor named Distinguished Professors

Interim USC President Wanda M. Austin has appointed Andrew P. McMahon as University Professor, and Kelvin J. A. Davies, Maja J. Matarić and Manuel Pastor Jr. as Distinguished Professors.

USC researchers converge at the Interdisciplinary Stem Cell Symposium

“The field of stem cell biology is one of our great convergence opportunities,” said USC Provost Michael Quick, addressing an audience of biologists, chemists, physicists, engineers, clinicians and many others. This diverse group came together for the Interdisciplinary Stem Cell Symposium, hosted by USC Stem Cell and the USC Medicine, Engineering, Science and Humanities (MESH) …

USC Stem Cell and BCRegMed Virtual Symposium brings Canada to California

It didn’t require plane tickets to bring together scientists from USC Stem Cell in Los Angeles and BCRegMed in Vancouver. During October’s Virtual Symposium, videoconferencing technology enabled these scientists to share ideas as if they were sitting in the same conference room—even though they were more than 1,200 miles apart.

USC Stem Cell scientist Andy McMahon and collaborators tune into the organ concert

Every minute of every day, your organs are using a complex language to communicate with each other about the basic physiological processes necessary for life—everything from blood pressure regulation to pH balance to metabolism. To decipher this little-known language, USC Stem Cell scientist Andy McMahon has joined forces with top scientists at Harvard and Stanford …

At the retreat for USC’s stem cell department, the students become the masters

Students and trainees took center stage at the annual retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. They presented their latest research to the 180 stem cell scientists who gathered at the event, held at the Pala Mesa Resort in Fallbrook, California this September.

From perfectly punctual to fashionably late, it takes all kinds to build a kidney

Running early or running late can have big consequences—especially when it comes to the progenitor cells involved in human kidney development. According to a new study in Developmental Cell from the USC Stem Cell laboratory of Andy McMahon, the progenitor cells that form the kidney’s filtering units, called nephrons, mature into entirely different types of …

Growing hope: New organs? Not yet, but stem cell research is getting closer

If you lose a limb, it’s lost for life. If you damage a kidney, you won’t grow a new one. And if you have a heart attack, the scars are there to stay. But regenerative medicine is poised to change all of this. Building new tissue is within sight, and USC scientists are among the …

Andrew P. McMahon, PhD, FRS

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