Stories

Pat Levitt (Photo courtesy of CHLA); featured image for Neural development of 2-month-old infants shows effect of maternal stress

Neural development of 2-month-old infants shows effect of maternal stress

Story courtesy of Children’s Hospital Los Angeles A study of 70 mothers and their infants suggests that the impact of maternal stress on neurodevelopment is detectable by electroencephalography (EEG) at 2 months …

Developing retina (Image by Cobrinik Lab); featured image for CHLA team identifies developmental stage for eye tumor in children

CHLA team identifies developmental stage for eye tumor in children

Investigators at Children’s Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The …

Pat Levitt (Photo courtesy of CHLA); featured image for Common psychiatric disorders share an overlapping genetic risk

Common psychiatric disorders share an overlapping genetic risk

Investigators found that many common psychiatric disorders are deeply connected on a genetic level, sharing specific genetic risk factors, underscoring the need to recognize shared dimensions of brain dysfunction, and develop new …

Killer T cells (green and red) surrounding a cancer cell (blue, center). (Image by Alex Ritter, Jennifer Lippincott Schwartz and Gillian Griffiths/National Institutes of Health); featured image for CHLA joins CureWorks collaborative to accelerate development of immunotherapy treatments for childhood cancers

CHLA joins CureWorks collaborative to accelerate development of immunotherapy treatments for childhood cancers

Seattle Children’s, with participating members Children’s Hospital Los Angeles, Children’s National Health System and BC Children’s Hospital, has launched CureWorks, an international collaborative of leading academic children’s hospitals determined to accelerate the …

Pat Levitt (Photo courtesy of CHLA); featured image for Patt Levitt named inaugural Chief Scientific Officer at CHLA

Patt Levitt named inaugural Chief Scientific Officer at CHLA

Pat Levitt, PhD, has been named Vice President, Chief Scientific Officer and Director of The Saban Research Institute of Children’s Hospital Los Angeles.

Baby Jasmine was born in late December with hypoplastic left heart syndrome (HLHS) and had her first open-heart surgery at five days old. She is enrolled in the groundbreaking clinical trial at Children’s Hospital Los Angeles. (Photo courtesy of CHLA); featured image for Children’s Hospital Los Angeles joins national consortium to study use of stem cells in treating a rare cardiac defect

Children’s Hospital Los Angeles joins national consortium to study use of stem cells in treating a rare cardiac defect

Children’s Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare …

Biodegradable scaffold (left) and human tissue-engineered liver (right) (Photo courtesy of The Saban Research Institute at Children’s Hospital Los Angeles); featured image for Functional human tissue-engineered liver generated from stem and progenitor cells

Functional human tissue-engineered liver generated from stem and progenitor cells

A research team led by investigators at The Saban Research Institute of Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells. Tissue-engineered Liver …

Tracy C. Grikscheit; featured image for Stem cell researcher Tracy Grikscheit awarded $7.1 million by CIRM

Stem cell researcher Tracy Grikscheit awarded $7.1 million by CIRM

Tracy C. Grikscheit, a principal investigator with USC Stem Cell and The Saban Research Institute of Children’s Hospital Los Angeles, has received a $7.1 million grant from the California Institute for Regenerative …

Tracy C. Grikscheit; featured image for Zebrafish provide a novel model to study short bowel syndrome

Zebrafish provide a novel model to study short bowel syndrome

USC Stem Cell investigators at Children’s Hospital Los Angeles (CHLA) are providing new hope for babies with short bowel syndrome (SBS) by developing a novel model of SBS in zebrafish, described in …

Coronary vasculature in zebrafish (Image courtesy of Children's Hospital Los Angeles)

Tiny heart, big promise

The heart has its own dedicated blood supply, with coronary arteries that supply oxygen-rich blood to the heart and cardiac veins that remove deoxygenated blood. This system of vessels nourishes the heart, …

Neonatal mouse heart showing basal level of proliferating cardiomyocytes (red: cardiomyocytes; green: proliferating cardiomyocytes; RV: right ventricle; LV: left ventricle). (Image courtesy of Ellen Lien); featured image for Mammalian heart regenerative capacity depends on severity of injury

Mammalian heart regenerative capacity depends on severity of injury

A new study by researchers at Children’s Hospital Los Angeles (CHLA) has shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury. Using cryoinjury — damaging the …

Andy McMahon, PhD, FRS (Photo by Cristy Lytal); featured image for Stem cells prove their potency at CHLA annual symposium

Stem cells prove their potency at CHLA annual symposium

The Saban Research Institute of Children’s Hospital Los Angeles Annual Symposium, held on Feb. 21, focused on the promise of regenerative medicine and cellular therapies — from curing HIV to building organs …

From left to right: Marvin Nelson, MD, MBA, Rex Moats, PhD, Brent Polk, MD, Elizabeth Garrett, JD, Scott Fraser, PhD, Carmen Puliafito, MD, MBA (Photo courtesy of Children's Hospital Los Angeles)

USC and Children’s Hospital Los Angeles launch imaging lab for translational research

With the launch of the Translational Biomedical Imaging Lab (TBIL), investigators at the University of Southern California (USC) and The Saban Research Institute of Children’s Hospital Los Angeles moved us closer to a …

Pat Levitt (Photo courtesy of Children's Hospital Los Angeles)

Pat Levitt elected to Institute of Medicine

Pat Levitt, provost professor of pediatrics, neuroscience, psychiatry, psychology and pharmacy at the Keck School of Medicine of USC, was recently elected as a member into the prestigious Institute of Medicine (IOM), …

Judy Villablanca (Photo courtesy of Children's Hospital Los Angeles)

Magnetic treatment for high-risk neuroblastoma proves less than attractive

Removing tumor cells with a magnet? It may sound strange, but researchers at Children’s Hospital Los Angeles (CHLA) and their colleagues recently explored whether this technique can create better outcomes for patients …