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Anika Gidwani

Where are they now? Stem cell master’s program alumna Anika Gidwani, a law student at the University of California, Davis

In this series of alumni profiles, we highlight graduates of USC’s master of science program in stem cell biology and regenerative medicine. Our accomplished alumni have pursued many different paths—ranging from a …

After surgical rib resection (top), a cartilage and bone bridge form (second from top) and then resolve (third from top) and remodel to regenerate the missing tissue in the gap (bottom). Blue shows cartilage matrix; red shows mineralized matrix. (Images by Stephanie Kuwahara and Max Serowoky/ Mariani Lab)

For large bone injuries, it’s Sonic hedgehog to the rescue

A USC Stem Cell study in NPJ Regenerative Medicine presents intriguing evidence that large bone injuries might trigger a repair strategy in adults that recapitulates elements of skeletal formation in utero. Key …

Eli Bosnoyan

As a graduate of USC’s stem cell master’s program, Eli Bosnoyan celebrates a Trojan Family that stretches from Syria to South LA

When Eli Bosnoyan first set foot on the USC campus, he was a six-year-old boy from Aleppo, Syria, visiting relatives in Los Angeles during his summer vacation. “I was with my brother,” …

USC's stem cell research center

California’s biggest stem cell experiment: The impact of the stem cell ballot proposition at USC

In 2008, USC broke ground on an $80 million building dedicated solely to stem cell research and regenerative medicine. The plans called for a monolithic structure clad in black marble and reflective …

Osteophyte

When it comes to arthritic bone spurs, stem cells hurt instead of heal

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of Rheumatic Diseases. “Although these stem and progenitor …

From right, USC Stem Cell scientists Francesca Mariani and Stephanie T. Kuwahara (Photo by Sergio Bianco)

Messenger cells bring good news for bone healing

How do bones heal, and how could they heal better? The answer to these questions may lie in a newly discovered population of “messenger” cells, according to a recent USC Stem Cell …

At the retreat for USC’s stem cell department, the students become the masters

Students and trainees took center stage at the annual retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. They presented their latest research to the 180 stem cell scientists who …

Growing hope: New organs? Not yet, but stem cell research is getting closer

If you lose a limb, it’s lost for life. If you damage a kidney, you won’t grow a new one. And if you have a heart attack, the scars are there to …

Mariani Lab reveals rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn’t even require barbecue sauce.

Scientists get into detail at the retreat for USC’s stem cell department

“The process of disease is about detail,” said Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s …

USC’s stem cell scientists secure the dollars to fight disease

The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous …

Artist plus researcher equals infinite inspiration at the Keck School of Medicine of USC

What happens when you pair 14 artists with 14 USC biomedical researchers? The answer is currently on display at the Hoyt Gallery on the Health Sciences Campus of the Keck School of …

From left, Gage Crump, Jay R. Lieberman and Francesca Mariani (Photo by Cristy Lytal)

Bone defects inspire perfect union between surgeon-scientist and stem cell researchers at USC

As chair of the Department of Orthopaedic Surgery at the Keck School of Medicine of USC, Jay R. Lieberman regularly sees patients with bone defects too severe to heal. This unmet clinical …

What I’m reading: Top pick from stem cell faculty member Francesca Mariani

In a recent study in the journal Cell, Kyle Loh and colleagues in Irving Weissman’s group established a rapid protocol for converting human pluripotent stem cells into mesoderm—the progenitors for heart, skeleton, …

A gene called Prkci helps organize organisms and their organs

A gene called Prkci can point cells in the right direction, according to a new study in Developmental Biology. In the study, USC Stem Cell researcher In Kyoung Mah from the laboratory …

USC Stem Cell researchers use zebrafish to understand the role of cartilage in bone repair

Scientists have long believed that the processes required for embryonic development are recapitulated during the regeneration of damaged body parts, such as fractured bones. In a new study published in Development, USC …

A Prkci gene keeps stem cells in check

When it comes to stem cells, too much of a good thing isn’t wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance …

Tri-institutional Stem Cell Retreat brings together Broad centers from USC, UCLA and UCSF

Working alone, a scientist or university can only make so much progress in finding answers to basic questions or new treatments for diseases ranging from HIV to cancer to diabetes. That’s why …

Halloween retreat showcases USC’s “scary smart” stem cell researchers

It was no tricks and all treats at the seventh annual retreat for the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, held at the university’s …

USC researchers discover the healing power of “rib tickling”

Unlike salamanders, mammals can’t regenerate lost limbs, but they can repair large sections of their ribs. In a new study in the Journal of Bone and Mineral Research, a team directed by …