Dr. Mariani’s laboratory studies the development and repair of the mammalian skeleton, with an emphasis on the ribs and handplate. They use standard and conditional knock-out techniques in mouse models and mouse embryonic stem (ES) cells.
Stories
USC’s stem cell scientists secure the dollars to fight disease
The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous …
Artist plus researcher equals infinite inspiration at the Keck School of Medicine of USC
What happens when you pair 14 artists with 14 USC biomedical researchers? The answer is currently on display at the Hoyt Gallery on the Health Sciences Campus of the Keck School of …
Bone defects inspire perfect union between surgeon-scientist and stem cell researchers at USC
As chair of the Department of Orthopaedic Surgery at the Keck School of Medicine of USC, Jay R. Lieberman regularly sees patients with bone defects too severe to heal. This unmet clinical …
What I’m reading: Top pick from stem cell faculty member Francesca Mariani
In a recent study in the journal Cell, Kyle Loh and colleagues in Irving Weissman’s group established a rapid protocol for converting human pluripotent stem cells into mesoderm—the progenitors for heart, skeleton, …
A gene called Prkci helps organize organisms and their organs
A gene called Prkci can point cells in the right direction, according to a new study in Developmental Biology. In the study, USC Stem Cell researcher In Kyoung Mah from the laboratory …
USC Stem Cell researchers use zebrafish to understand the role of cartilage in bone repair
Scientists have long believed that the processes required for embryonic development are recapitulated during the regeneration of damaged body parts, such as fractured bones. In a new study published in Development, USC …
A Prkci gene keeps stem cells in check
When it comes to stem cells, too much of a good thing isn’t wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance …
Tri-institutional Stem Cell Retreat brings together Broad centers from USC, UCLA and UCSF
Working alone, a scientist or university can only make so much progress in finding answers to basic questions or new treatments for diseases ranging from HIV to cancer to diabetes. That’s why …
Halloween retreat showcases USC’s “scary smart” stem cell researchers
It was no tricks and all treats at the seventh annual retreat for the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, held at the university’s …
USC researchers discover the healing power of “rib tickling”
Unlike salamanders, mammals can’t regenerate lost limbs, but they can repair large sections of their ribs. In a new study in the Journal of Bone and Mineral Research, a team directed by …
USC Stem Cell and the USC Norris Comprehensive Cancer Center accelerate drug discovery
Three teams of USC stem cell researchers have won a coveted prize — the opportunity to test 3,000 drug candidates or chemicals for the potential to help patients. Two teams will focus …
A Retreat from everything but stem cells
It wasn’t the pristine 27-hole course that drew more than 120 stem cell researchers from USC and beyond to the Desert Princess Golf Resort near Palm Springs. It was the sixth annual …
Winner of the September 2013 USC Stem Cell Image of the Month Contest
Dr. Andrew McMahon, Dr. Seth Ruffins and the judges of the USC Stem Cell Image of the Month contest would like to congratulate our September 2013 winner, In Kyoung Mah, a graduate …
USC announces winners of first Regenerative Medicine Initiative awards
Three newly assembled disease teams within USC Stem Cell will take the early steps this year that might lead to future stem-cell based therapies for certain forms of deafness, bone defects and …