Dr. Crump uses zebrafish to understand how the cartilages and bones of our faces are patterned during development. His lab is discovering the local tissue-tissue interactions that control skeletal differentiation and morphogenesis in vivo, and also exploring novel ways of regenerating bone in adults.

Stories

The joint cells are the ones that are not outlined in black. (Image by Amjad Askary and Lindsey Mork/Crump Lab); featured image for Iroquois genes make cartilage cells act “oh so immature”

Iroquois genes make cartilage cells act “oh so immature”

Arthritis, the leading cause of disability in the U.S., involves the loss of a special type of cartilage cell lining the joints. In a study appearing on the cover of the latest …

Gage Crump gives USC undergraduates a stem cell primer. (Photo by Cristy Lytal); featured image for USC undergraduates get a dose of stem cells in two new MEDS courses

USC undergraduates get a dose of stem cells in two new MEDS courses

Science fiction author Margaret Atwood has frequently stated that biotechnology itself is neutral. It is how people use it that is good or bad. In the new spring course MEDS 380 Stem …

From left, Lindsey Barske, Michael Patterson, Ang Li and Yuwei Li (Photos by Cristy Lytal); featured image for USC postdocs win Doerr Stem Cell Challenge Grants

USC postdocs win Doerr Stem Cell Challenge Grants

Just as there are times when two heads are better than one, there are times when two labs are better than one. Thanks to the new Doerr Stem Cell Challenge Grants, teams …

“Tin Woman” Michaela Patterson, a postdoctoral scholar in the lab of Henry Sucov, studies heart regeneration — with no help from the Wizard of Oz. (Photo by Cristy Lytal); featured image for Halloween retreat showcases USC’s “scary smart” stem cell researchers

Halloween retreat showcases USC’s “scary smart” stem cell researchers

It was no tricks and all treats at the seventh annual retreat for the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, held at the university’s …

Gage Crump; featured image for New stem cell course brings together science and fiction

New stem cell course brings together science and fiction

Video by Alric Devotta USC will be offering a new two-unit class next spring, MEDS 380 Stem Cells: Fact and Fiction, which will explore contemporary topics in stem cell biology and innovative …

Dissection of the larval zebrafish skeleton shows facial cartilage (blue) and bone (red) (Image courtesy of the Crump Lab); featured image for USC researchers reveal how gene expression affects facial expressions

USC researchers reveal how gene expression affects facial expressions

A person’s face is the first thing that others see, and much remains unknown about how it forms — or malforms — during early development. Recently, Chong Pyo Choe, a senior postdoctoral fellow working …

Neil Segil, PhD, (right) gets a glimpse into retinal regeneration. (Photo by Cristy Lytal); featured image for USC stem cell PhD students present their blueprints for rebuilding the body

USC stem cell PhD students present their blueprints for rebuilding the body

Video by Alric Devotta The students in the new PhD program in Development, Stem Cells, and Regenerative Medicine recently presented some ideas that would give Dr. Frankenstein a run for his money. …

Human skull with sutures; featured image for USC, UCLA and UCSF put their heads together to find stem cell-based cures for craniofacial defects

USC, UCLA and UCSF put their heads together to find stem cell-based cures for craniofacial defects

One in every 2,000 babies is born with a skull that can’t grow normally. Various sections of these babies’ skulls are fused together at joints called sutures, constricting the developing brain and …

Multi-well plate (Image courtesy of the National Institutes of Health); featured image for USC Stem Cell and the USC Norris Comprehensive Cancer Center accelerate drug discovery

USC Stem Cell and the USC Norris Comprehensive Cancer Center accelerate drug discovery

Three teams of USC stem cell researchers have won a coveted prize — the opportunity to test 3,000 drug candidates or chemicals for the potential to help patients. Two teams will focus …

Lindsey Barske (Photo by Cristy Lytal); featured image for Postdocs receive Giannini Foundation fellowships

Postdocs receive Giannini Foundation fellowships

Two Keck School of Medicine of USC postdoctoral scholars recently received fellowships from the prestigious A.P. Giannini Foundation. Lindsey Barske, PhD, received her fellowship based on her work with craniofacial development, and …

A look inside the ear of a mouse, with the middle ear ossicles off-centered (Image by Camilla Teng); featured image for Winner of the January 2014 USC Stem Cell Image of the Month Contest

Winner of the January 2014 USC Stem Cell Image of the Month Contest

Dr. Andy McMahon and the judges of the USC Stem Cell Image of the Month contest would like to congratulate our January 2014 winner, Camilla Teng, a graduate student in Dr. Rob …

Keynote speaker Clive Svendsen (right) and Director Andy McMahon; featured image for A Retreat from everything but stem cells

A Retreat from everything but stem cells

It wasn’t the pristine 27-hole course that drew more than 120 stem cell researchers from USC and beyond to the Desert Princess Golf Resort near Palm Springs. It was the sixth annual …

Compared with a normal zebrafish (top), this mutant (bottom) is a real bone head. (Image by Sandeep Paul and Seth Ruffins); featured image for Winner of the August 2013 USC Stem Cell Image of the Month Contest

Winner of the August 2013 USC Stem Cell Image of the Month Contest

Dr. Andrew McMahon and the judges of the USC Stem Cell Image of the Month contest would like to congratulate our August 2013 winners, Dr. Seth Ruffins and Sandeep Paul, a postdoc …

From left, Gage Crump, Jay R. Lieberman and Francesca Mariani (Photo by Cristy Lytal); featured image for USC announces winners of first Regenerative Medicine Initiative awards

USC announces winners of first Regenerative Medicine Initiative awards

Three newly assembled disease teams within USC Stem Cell will take the early steps this year that might lead to future stem-cell based therapies for certain forms of deafness, bone defects and …

Gage Crump; featured image for Discovery of genetic clues may lead to better grasp of birth defects

Discovery of genetic clues may lead to better grasp of birth defects

Using cutting-edge time-lapse photography, Keck School of Medicine researchers have discovered clues to the development of the head at the cellular level, which could point scientists to a better understanding of how …

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC (Photo by Chris Shinn); featured image for Keck student honored with PhD Achievement Award

Keck student honored with PhD Achievement Award

Keck School of Medicine scholar Elizabeth Zuniga is one of five USC graduate students to receive the PhD Achievement Award this month in recognition of their outstanding academic profiles. New this year, …