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Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs the kidney and urinary system. They are also developing new regenerative treatments for the millions of patients with kidney injury and disease, bladder injury and disease, and urinary incontinence.

Statistics

  • One in 10 adults in the U.S.—more than 20 million people—are suffering from some degree of chronic kidney disease. Common causes include diabetes and high blood pressure.
  • 13 million people in the U.S. experience urinary incontinence, frequently as a result of childbirth.

Researchers

News

kidney organoid

USC Stem Cell scientists make big progress in building mini-kidneys

A team of scientists at the Keck School of Medicine of USC has created what could be a key building block for assembling a synthetic kidney. In a new study in Nature Communications, Zhongwei Li and his colleagues describe how they can generate rudimentary kidney structures, known as organoids, that resemble the collecting duct system …

Leonardo Morsut

USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development

Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment. To begin unraveling this complexity, USC Stem Cell scientist Leonardo Morsut is designing artificial genetic programs to perturb natural signaling networks and study how this …

Impromptu McMahon lab meeting

USC Stem Cell study identifies molecular “switch” that turns precursors into kidney cells

Kidney development is a balancing act between the self-renewal of stem and progenitor cells to maintain and expand their numbers, and the differentiation of these cells into more specialized cell types. In a new study in the journal eLife from Andy McMahon’s laboratory in the Department of Stem Cell Biology and Regenerative Medicine at the …

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Multimedia

The University of Southern California has designed a unique “incubator” for scientists, engineers and clinicians to collaborate across disciplines and leverage the transformative power of stem cells to develop the future of regenerative medicine. The USC Stem Cell incubator trains the next generation of scientists through a dedicated PhD program and first-of-its-kind master’s degree, and brings together leading researchers from around the world to gain insights into developmental biology and advance new treatments for human disease. Learn more at http://stemcell.keck.usc.edu.
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