Overview

USC Stem Cell scientists are advancing our understanding of how the body develops, maintains and repairs the brain, nerves and senses. They are using stem cells to find new regenerative therapies for conditions including Alzheimer’s disease, neurodegenerative diseases, brain tumors, hearing loss and vision loss.

Statistics

  • Alzheimer’s disease is the sixth leading cause of death in the US. An estimated 5.5 million Americans are living with Alzheimer’s disease.
  • ALS, or Lou Gehrig’s disease, causes progressive paralysis and usually results in fatal respiratory failure within three to five years of diagnosis.
  • Brain tumors are the most common cancer and leading cause of cancer-related death in children fourteen years and younger.
  • Twenty percent of Americans—or 48 million people—report some degree of hearing loss.
  • More than 20 million Americans report some degree of vision loss.

Researchers

Brain, Nerves and Senses News

USC Stem Cell scientists watched the sun set over the Pacific Ocean during a Q&A with keynote speaker Aileen Anderson. (Photo by Cristy Lytal)

Getting lost in translation—the clinical kind—at USC’s stem cell retreat

At the retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine, newly appointed leader Chuck Murry shared a vision as sweeping as the panoramic view of the Pacific Ocean from …

Müller glia (green) and their progeny (red) regenerate nerve cells and photoreceptors in a mouse retina (Image by Ksenia Gnedeva/USC)

USC Stem Cell mouse study identifies shared genes involved in hearing and vision regeneration

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, published in …

Tau protein in the brain of a mouse with a mutation that causes a common form of dementia (Image by Joshua Berlind/Ichida Lab/USC Stem Cell)

How to clear the toxic tau protein that can lead to Alzheimer’s and related diseases

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids. The neurotransmitter glutamate is essential …

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Brain, Nerves and Senses Videos

Dr. Justin Ichida’s research focuses on how genetic and environmental factors contribute to human neurodegenerative disease. His laboratory uses cellular reprogramming and stem cell technology to build patient-specific in vitro models of neurodegenerative disease, enabling the screening of drug-like compounds in search of potential therapeutics. To learn more, visit https://ichidalab.usc.edu.
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