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Illustration by Jonathan Haase

Cycles of a fasting-mimicking diet help mice live longer, healthier

While many diets have been studied for effectiveness in preventing obesity and heart disease in both mice and humans, research on the effects and benefits of short, periodic cycles of fasting on obesity and heart health are lacking. In a new USC study on the health effects of a low-calorie diet that mimics …

fasting and breast cancer

Studies suggest a fasting diet could boost breast cancer therapy

A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical …

Oranges

Fasting plus vitamin C proves effective for hard-to-treat cancers

Scientists from USC and the IFOM Cancer Institute in Milan have found that a fasting-mimicking diet could be more effective at treating some types of cancer when combined with vitamin C. In multiple …

Time to eat

What and when we eat affects our immune system. Here’s how.

Professor Valter Longo, director of the USC Longevity Institute, is investigating how fasting and diets that mimic fasting’s effects can help immune function, including vaccine efficacy and the body’s response to infection …

(Illustration by Chris Gash)

Eat less, live longer? The science of fasting and longevity

When it comes to what, when and how we eat, fasting — voluntarily abstaining from food for varying periods of time — is having a moment. It was the most popular diet …

Fasting-mimicking diet holds promise for treating people with inflammatory bowel disease, USC study finds

What if a special diet could reduce inflammation and repair your gut? USC researchers provided evidence that a low-calorie “fasting-mimicking” diet has the potential to do just that. Published in the March …

USC researchers converge at the Interdisciplinary Stem Cell Symposium

“The field of stem cell biology is one of our great convergence opportunities,” said USC Provost Michael Quick, addressing an audience of biologists, chemists, physicists, engineers, clinicians and many others. This diverse …

TIME names Valter Longo one of the 50 Most Influential People in Health Care of 2018

USC Leonard Davis School Professor Valter Longo, director of the USC Longevity Institute and USC Stem Cell principal investigator, has been named one of TIME’s the 50 Most Influential People in Health …

Five ways to lower your chances of getting Alzheimer’s

Retain a sharp, healthy brain and reduce your risk of Alzheimer’s disease by following five simple rules. Some of the tips are scientifically proven, while others show promise but require further investigation.

What to know about fasting, aging, the “longevity diet” and when you should eat

Biochemist Valter Longo has devoted decades to discovering connections between nutrition and successful aging. He runs the Longevity Institute at the USC Leonard Davis School of Gerontology, which aims to extend healthy …

Drugs widely used in cancer therapy increase toxicity of chemotherapy in mice

A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research by …

Fasting-mimicking diet may reverse diabetes in mice

By Beth Newcomb A diet designed to imitate the effects of fasting appears to reverse diabetes, a new USC-led study shows. The fasting-like diet promotes the growth of new insulin-producing pancreatic cells …

Scientifically-designed fasting diet lowers risks for major diseases

What if you could lose weight and reduce your risk of life-threatening disease without any changes in what you eat—other than a five-day special diet once every few months? That’s what happened …

Diet that mimics fasting may also reduce multiple sclerosis symptoms

Evidence is mounting that a diet mimicking the effects of fasting has health benefits beyond weight loss, with a new USC-led study indicating that it may reduce symptoms of multiple sclerosis. Scientists …

Diet that mimics fasting appears to slow aging

Want to lose abdominal fat, get smarter and live longer? New research led by USC Stem Cell principal investigator Valter Longo shows that periodically adopting a diet that mimics the effects of …

USC Stem Cell Symposium creates scientific synergy

Provost Michael Quick convened the inaugural USC Stem Cell Symposium with a straightforward truth about the future of regenerative medicine: “it will take a dedicated community of scholars across the disciplines to …

USC hosts California stem cell agency’s tenth birthday bash

Few 10 year olds have brought 10 potential medical treatments into clinical trials. The California Institute for Regenerative Medicine (CIRM), however, is a truly exceptional 10 year old. In 2004, the people …

Fasting triggers stem cell regeneration of damaged, old immune system

In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study in the June 5 issue of Cell Stem Cell shows that cycles of …

USC Stem Cell researchers share a vision of the future at the Milken Institute Global Conference

What do former British Prime Minister Tony Blair and singer Will.i.am have in common? They both attended this year’s Milken Institute Global Conference, where USC Stem Cell researchers offered an exciting glimpse …

Valter Longo seeks a recipe for longevity

Video by the USC Davis School of Gerontology Valter Longo, PhD, principal investigator with USC Stem Cell, is out to prove that gerontology is a young man’s game — just like rock …

Valter Longo, PhD