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C. Thomas Vangsness, Jr. (Photo by Cristy Lytal)

CIRM awards $2.29 million to support stem cell-based therapy for knee osteoarthritis

The California Institute for Regenerative Medicine (CIRM), California’s stem cell agency, has awarded the biopharmaceutical company Cellular Biomedicine Group Inc. (Nasdaq: CBMG) $2.29 million to support pre-clinical studies of AlloJoinTM, human fat-derived …

Megan McCain (Photo by Will Taylor)

Bioengineering models for muscular dystrophy research

Studying muscular diseases proves extremely complicated. The current system of studying muscle cells and tissues using animal models is often inconclusive and cost-prohibitive. Looking to improve the status quo, Megan McCain—a Gabilan …

From left, Gage Crump, Jay R. Lieberman and Francesca Mariani (Photo by Cristy Lytal)

Bone defects inspire perfect union between surgeon-scientist and stem cell researchers at USC

As chair of the Department of Orthopaedic Surgery at the Keck School of Medicine of USC, Jay R. Lieberman regularly sees patients with bone defects too severe to heal. This unmet clinical …

Denis Evseenko (Photo by Cristy Lytal)

Denis Evseenko receives $2.5 million from California Institute for Regenerative Medicine for osteoarthritis research

The Keck School of Medicine of the University of Southern California (USC) is one of four institutions to receive a multi-million dollar grant from the California Institute for Regenerative Medicine (CIRM) for …

Joseph T. Rodgers (Photo by Cristy Lytal)

USC Stem Cell scientist Joseph T. Rodgers receives grant from the American Federation for Aging Research (AFAR)

Wisdom can increase with age, but healing power does not. USC Stem Cell scientist Joseph T. Rodgers is exploring the biology behind this fact, thanks to a grant from the American Federation …

Senta Georgia (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Senta Georgia

Earlier this year, a team at the Karolinska Institute published a paper that profiled gene activity in single cells from human embryos created in the context of in vitro fertilization. Now this …

Qi-Long Ying (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Qi-Long Ying

In a recent study published in Cell Stem Cell, Joshua Black and colleagues demonstrated that skin cells are converted into neurons using a powerful tool called CRISPR/Cas9 to concurrently modify and activate …

Wange Lu (Photo by Chris Shinn)

What I’m reading: Top pick from stem cell faculty member Wange Lu

Our genetic material is packed into the nucleus of the cell, but is the packing process random or organized in some way? In a recent study published in Cell Stem Cell, Krijger …

Megan McCain (Photo by Will Taylor)

Megan McCain receives American Heart Association Faculty Award

Megan McCain has received a 2016 Scientist Development Grant from the American Heart Association. The three-year, $231,000 grant supports highly promising early career scientists in cardiovascular and stroke research. McCain—Gabilan Assistant Professor …

Human skull with sutures (Public domain image courtesy of Gray's Anatomy)

USC researchers awarded $3.3 million NIDCR grant to find more effective treatment for common birth defect

It might surprise you to learn that your cranium is not one continuous smooth bone encasing your brain. It’s actually comprised of eight bones, separated by fibrous joints, to give your skull …

Francesca Mariani (Photo by Chris Shinn)

What I’m reading: Top pick from stem cell faculty member Francesca Mariani

In a recent study in the journal Cell, Kyle Loh and colleagues in Irving Weissman’s group established a rapid protocol for converting human pluripotent stem cells into mesoderm—the progenitors for heart, skeleton, …

Joseph T. Rodgers (Photo by Cristy Lytal)

What I’m reading: A top pick from stem cell faculty member Joseph T. Rodgers

In a recent issue of Science, Jay Shendure, Alexander Schier and colleagues present an extraordinarily powerful new approach to trace the lineage of cells as they divide within an organism.

From left, Andy McMahon and Gage Crump (Photos by Phil Channing and the Crump Lab)

What I’m reading: Top picks from stem cell faculty members Andy McMahon and Gage Crump

Andy McMahon: Leigh Turner and Paul Knoepfler present a disturbing report in Cell Stem Cell on the growth of businesses marketing stem cell interventions in the US. Los Angeles is one “stem …

Adult zebrafish jaw joint (Image by Amjad Askary)

Arthritis originated in primordial fish

We all know someone affected by arthritis—as well as that old dog down the block. But according to a new study in eLife, arthritis is much more widespread in the animal kingdom …

Lindsey Barske (Photo by Cristy Lytal)

USC Stem Cell scientist Lindsey Barske wins NIH Pathway to Independence Award

Years ago, Lindsey Barske pulled on a pair of tall rubber boots and began a journey that led from her college research experience on the muddy Alaskan tundra to her current postdoctoral …

Skeletal myotubes grown for three weeks on gelatin hydrogel (Image by Archana Bettadapur, Gio Suh, Evelyn Wang, Holly Huber, Alyssa Viscio and Megan McCain)

USC researchers use gelatin instead of the gym to grow stronger muscles

USC researcher Megan L. McCain and colleagues have devised a way to develop bigger, stronger muscle fibers. But instead of popping up on the bicep of a bodybuilder, these muscles grow on …

From left, Broad Clinical Research Fellows Christopher Schlieve, Gene K. Lee and R. Kiran Alluri

USC Stem Cell names second cohort of Broad Clinical Research Fellows

The second cohort of Broad Clinical Research Fellows is making strides towards finding stem cell-based therapies for lymphedema in cancer patients, large bone fractures and short bowel syndrome.

Stem cells self-organize to form a hollow ball of cells. (Image by In Kyoung Mah and Francesca Mariani)

A gene called Prkci helps organize organisms and their organs

A gene called Prkci can point cells in the right direction, according to a new study in Developmental Biology. In the study, USC Stem Cell researcher In Kyoung Mah from the laboratory …

Joseph T. Rodgers (Photo by Cristy Lytal)

Joseph T. Rodgers and Hyungjin Eoh win Baxter Awards

Directors of the Donald E. and Delia B. Baxter Foundation visited the USC Health Sciences Campus this May, to hear presentations from Keck School of Medicine of USC faculty and meet with …

Denis Evseenko (Photo by Cristy Lytal)

Denis Evseenko is featured on Arthritis Now

Listen to an interview with USC Stem Cell scientist Denis Evseenko. It’s featured on Arthritis Now, a web series produced by the Arthritis National Research Foundation. The Evseenko Lab research program is …