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The protein TAZ (green) in the cytoplasm (the region outside of the nuclei, blue) promotes the self-renewal of human embryonic stem cells. (Image by Xingliang Zhou); featured image for The protein TAZ sends “mixed signals” to stem cells

The protein TAZ sends “mixed signals” to stem cells

Just as beauty exists in the eye of the beholder, a signal depends upon the interpretation of the receiver. According to new USC research published in Stem Cell Reports, a protein called …

From left, Qi-Long Ying, Min Zhou, and Ying Lab postdoc Shi (Steve) Yue (Photo by Cristy Lytal); featured image for Biotech entrepreneur Min Zhou supports scientific serendipity in the USC Stem Cell laboratory of Qi-Long Ying

Biotech entrepreneur Min Zhou supports scientific serendipity in the USC Stem Cell laboratory of Qi-Long Ying

“The most important discoveries that I’ve made have all come from nowhere,” said Qi-Long Ying, associate professor of stem cell biology and regenerative medicine at USC. “They could not be planned.” To …

Rat; featured image for USC Stem Cell researchers receive $3 million of NIH funding to produce sophisticated laboratory rats

USC Stem Cell researchers receive $3 million of NIH funding to produce sophisticated laboratory rats

USC Stem Cell principal investigator Qi-Long Ying and his team are pleased to introduce a new transgenic animal—the conditional and inducible gene knockout rat. Created using embryonic stem cell-based technology, these remarkable …

Rong Lu (Photo by Cristy Lytal); featured image for New USC stem cell course teaches how to design an experiment

New USC stem cell course teaches how to design an experiment

For future scientists, few skills are more essential than the ability to design a good experiment. In a new spring 2018 course, SCRM 517 Historical and Contemporary Stem Cell Research, Professor Rong …

Pluripotency (Painting by Amanda Kwieraga); featured image for USC alumna Amanda Kwieraga makes paintings from acrylic, wood and stem cell science

USC alumna Amanda Kwieraga makes paintings from acrylic, wood and stem cell science

“Anyone who views something under a microscope or through a telescope will tell you that science is art, and that art is the perfect way to convey science,” said Amanda Kwieraga, an …

Human development (Image courtesy of Evseenko Lab); featured image for Whittier Foundation backs new group of research projects

Whittier Foundation backs new group of research projects

The L.K. Whittier Foundation has been a critical source of funding for cancer research at the Keck School of Medicine of USC and the USC Norris Comprehensive Cancer Center, supporting clinicians and …

From left, Broad Clinical Research Fellows Wan Jiao, Roshan Rajani and Anthony Squillaro (Photos courtesy of Wan Jiao, Cristy Lytal and Anthony Squillaro); featured image for Broad Clinical Research Fellows strive to regenerate lymph nodes, liver and kidney

Broad Clinical Research Fellows strive to regenerate lymph nodes, liver and kidney

The lymph nodes, liver and kidney are not passive filters for toxins, but complex organ systems that perform an astonishing array of critical functions. To help patients who have suffered damage to …

Lisa Nguyen (Photo by Cristy Lytal); featured image for Meet PhD student Lisa Nguyen, presenter at the ISSCR 2017 Annual Meeting

Meet PhD student Lisa Nguyen, presenter at the ISSCR 2017 Annual Meeting

Ask Lisa Nguyen what gets her blood racing, and her answer will be hematopoietic stem cells, or HSCs. She’ll be presenting about HSCs, which form the blood and immune systems, at the …

Clockwise from top left: Andy McMahon, Rohit Varma, Jonathan Samet and Donna Spruijt-Metz (Photos courtesy of USC); featured image for NIH funding helps Americans live longer and healthier

NIH funding helps Americans live longer and healthier

The nation’s medical research agency, the National Institutes of Health, funds research to help Americans live longer and healthier. Some 148 Nobel Prize winners have received support from the NIH, demonstrating how …

Kidney organoid (Image by Tracy Tran/McMcMahon Lab); featured image for USC’s stem cell scientists secure the dollars to fight disease

USC’s stem cell scientists secure the dollars to fight disease

The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous …

Barbara Kolo and Andy McMahon (Photo by Richard Carrasco); featured image for Artist plus researcher equals infinite inspiration at the Keck School of Medicine of USC

Artist plus researcher equals infinite inspiration at the Keck School of Medicine of USC

What happens when you pair 14 artists with 14 USC biomedical researchers? The answer is currently on display at the Hoyt Gallery on the Health Sciences Campus of the Keck School of …

Leonardo Morsut (Photo by Cristy Lytal); featured image for From professional volleyball to stem cell biology, Leonardo Morsut is at the top of his game

From professional volleyball to stem cell biology, Leonardo Morsut is at the top of his game

For USC Stem Cell researcher Leonardo Morsut, the word “set” refers to a collection of scientific data. “Set” is also the prelude to spiking a volleyball over the net—something he used to do for a living as a professional athlete in Italy.

Valter Longo (Photo by John Skalicky); featured image for Drugs widely used in cancer therapy increase toxicity of chemotherapy in mice

Drugs widely used in cancer therapy increase toxicity of chemotherapy in mice

A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research by …

Jian Xu (Photo courtesy of the Ostrow School of Dentistry of USC); featured image for Researcher Jian Xu earns accolades for cell fate studies

Researcher Jian Xu earns accolades for cell fate studies

Basic science can often be far from basic—especially for Jian Xu, who believes cells are kind of like people. “In simple terms, we look at how cells determine their own fate,” said …

Valter Longo (Photo by Dietmar Quistorf); featured image for Scientifically-designed fasting diet lowers risks for major diseases

Scientifically-designed fasting diet lowers risks for major diseases

What if you could lose weight and reduce your risk of life-threatening disease without any changes in what you eat—other than a five-day special diet once every few months? That’s what happened …

Keyue Shen; featured image for Beating the spread

Beating the spread

Cancer cells are like normal cells, only trickier. They carry genetic mutations that can hoodwink their surroundings to favor their growth. Using biologically inspired in vitro models, Keyue Shen, an assistant professor …

Senta Georgia (Photo by Cristy Lytal); featured image for What I’m Reading: Top pick from stem cell faculty member Senta Georgia

What I’m Reading: Top pick from stem cell faculty member Senta Georgia

Earlier this year, a team at the Karolinska Institute published a paper that profiled gene activity in single cells from human embryos created in the context of in vitro fertilization. Now this …

Qi-Long Ying (Photo by Cristy Lytal); featured image for What I’m Reading: Top pick from stem cell faculty member Qi-Long Ying

What I’m Reading: Top pick from stem cell faculty member Qi-Long Ying

In a recent study published in Cell Stem Cell, Joshua Black and colleagues demonstrated that skin cells are converted into neurons using a powerful tool called CRISPR/Cas9 to concurrently modify and activate …

Wange Lu (Photo by Chris Shinn); featured image for What I’m reading: Top pick from stem cell faculty member Wange Lu

What I’m reading: Top pick from stem cell faculty member Wange Lu

Our genetic material is packed into the nucleus of the cell, but is the packing process random or organized in some way? In a recent study published in Cell Stem Cell, Krijger …

Min Yu (Photo by Cristy Lytal); featured image for What I’m reading: Top pick from stem cell faculty member Min Yu

What I’m reading: Top pick from stem cell faculty member Min Yu

In a recent issue of Cell, William Greenleaf, Monte Winslow and colleagues have characterized differences within primary and metastatic tumors in an engineered mouse model of small cell lung cancer (SCLC). Many …