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Clockwise from top left: Andy McMahon, Rohit Varma, Jonathan Samet and Donna Spruijt-Metz (Photos courtesy of USC)

NIH funding helps Americans live longer and healthier

The nation’s medical research agency, the National Institutes of Health, funds research to help Americans live longer and healthier. Some 148 Nobel Prize winners have received support from the NIH, demonstrating how …

Kidney organoid (Image by Tracy Tran/McMcMahon Lab)

USC’s stem cell scientists secure the dollars to fight disease

The price of progress is not only the energy and talent of stem cell scientists, but also the research dollars that support their discoveries. In recent months, faculty members have secured numerous …

Barbara Kolo and Andy McMahon (Photo by Richard Carrasco)

Artist plus researcher equals infinite inspiration at the Keck School of Medicine of USC

What happens when you pair 14 artists with 14 USC biomedical researchers? The answer is currently on display at the Hoyt Gallery on the Health Sciences Campus of the Keck School of …

Leonardo Morsut (Photo by Cristy Lytal)

From professional volleyball to stem cell biology, Leonardo Morsut is at the top of his game

For USC Stem Cell researcher Leonardo Morsut, the word “set” refers to a collection of scientific data. “Set” is also the prelude to spiking a volleyball over the net—something he used to do for a living as a professional athlete in Italy.

Valter Longo (Photo by John Skalicky)

Drugs widely used in cancer therapy increase toxicity of chemotherapy in mice

A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research by …

Jian Xu (Photo courtesy of the Ostrow School of Dentistry of USC)

Researcher Jian Xu earns accolades for cell fate studies

Basic science can often be far from basic—especially for Jian Xu, who believes cells are kind of like people. “In simple terms, we look at how cells determine their own fate,” said …

Valter Longo (Photo by Dietmar Quistorf)

Scientifically-designed fasting diet lowers risks for major diseases

What if you could lose weight and reduce your risk of life-threatening disease without any changes in what you eat—other than a five-day special diet once every few months? That’s what happened …

Keyue Shen

Beating the spread

Cancer cells are like normal cells, only trickier. They carry genetic mutations that can hoodwink their surroundings to favor their growth. Using biologically inspired in vitro models, Keyue Shen, an assistant professor …

Senta Georgia (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Senta Georgia

Earlier this year, a team at the Karolinska Institute published a paper that profiled gene activity in single cells from human embryos created in the context of in vitro fertilization. Now this …

Qi-Long Ying (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Qi-Long Ying

In a recent study published in Cell Stem Cell, Joshua Black and colleagues demonstrated that skin cells are converted into neurons using a powerful tool called CRISPR/Cas9 to concurrently modify and activate …

Wange Lu (Photo by Chris Shinn)

What I’m reading: Top pick from stem cell faculty member Wange Lu

Our genetic material is packed into the nucleus of the cell, but is the packing process random or organized in some way? In a recent study published in Cell Stem Cell, Krijger …

Min Yu (Photo by Cristy Lytal)

What I’m reading: Top pick from stem cell faculty member Min Yu

In a recent issue of Cell, William Greenleaf, Monte Winslow and colleagues have characterized differences within primary and metastatic tumors in an engineered mouse model of small cell lung cancer (SCLC). Many …

Joseph T. Rodgers (Photo by Cristy Lytal)

What I’m reading: A top pick from stem cell faculty member Joseph T. Rodgers

In a recent issue of Science, Jay Shendure, Alexander Schier and colleagues present an extraordinarily powerful new approach to trace the lineage of cells as they divide within an organism.

From left, Andy McMahon and Gage Crump (Photos by Phil Channing and the Crump Lab)

What I’m reading: Top picks from stem cell faculty members Andy McMahon and Gage Crump

Andy McMahon: Leigh Turner and Paul Knoepfler present a disturbing report in Cell Stem Cell on the growth of businesses marketing stem cell interventions in the US. Los Angeles is one “stem …

Valter Longo (Photo by John Skalicky)

Fasting-like diet turns the immune system against cancer

A fasting-like diet with chemotherapy strips away the guard that protects breast cancer and skin cancer cells from the immune system, according to a new USC-led study on mice. The study was …

From top: Dion Dickman (left), Megan McCain and Justin Ichida; Rong Lu (left) and Keyue Shen (Photos by Cristy Lytal)

USC Stem Cell researchers receive the inaugural Broad Innovation Awards

Two teams of scientists have won the inaugural Eli and Edythe Broad Innovation Awards in Stem Cell Biology and Regenerative Medicine at USC. This year’s competition provides $120,000 each to the teams …

From left, Broad Clinical Research Fellows Christopher Schlieve, Gene K. Lee and R. Kiran Alluri

USC Stem Cell names second cohort of Broad Clinical Research Fellows

The second cohort of Broad Clinical Research Fellows is making strides towards finding stem cell-based therapies for lymphedema in cancer patients, large bone fractures and short bowel syndrome.

Stem cells self-organize to form a hollow ball of cells. (Image by In Kyoung Mah and Francesca Mariani)

A gene called Prkci helps organize organisms and their organs

A gene called Prkci can point cells in the right direction, according to a new study in Developmental Biology. In the study, USC Stem Cell researcher In Kyoung Mah from the laboratory …

Clockwise from top left: Study authors Casey Brewer, Elizabeth Chu, Rong Lu and Mike Chin (Photos by Cristy Lytal)

Dose of transplanted blood-forming stem cells affects their behavior

Unlike aspirin, bone marrow doesn’t come with a neatly printed label with dosage instructions. However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow …

The Journal of Neuroscience cover from April 27, 2016

Key mutations may worsen hearing loss from the chemotherapy drug cisplatin

The chemotherapy drug cisplatin can kill cancer, but it can also kill the sensory cells of the inner ear — causing permanent hearing loss. This hearing loss is likely to be more severe …