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Robert E. Maxson

USC celebrates Robert E. Maxson’s lifetime of achievement and adventure

USC Emeritus Professor Robert E. Maxson has an understated explanation for why he’s flown so many planes, sailed so many boats, skied so many mountains, played so many guitars, taken so many trips to Antarctica, and studied so many different aspects of developmental biology. “I’m drawn to things that take all my attention, and things …

Leonardo Morsut

USC Stem Cell scientist Leonardo Morsut awarded $2.5 million NIH grant to explore “synthetic” embryonic development

Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment. To begin unraveling this complexity, USC Stem Cell scientist Leonardo Morsut is designing artificial genetic programs to perturb natural signaling networks and study how this …

Xi Chen

For USC scientist Xi Chen, a chicken is more than just an egg’s way of making another egg

USC postdoctoral researcher Xi Chen knows that you have to break a few eggs in order to grow chicken stem cells. His work on maintaining embryonic stem cells (ESC) from chicken eggs provides insight into stem cell pluripotency and evolutionary developmental biology. “The choice of beginning with fertilized chicken eggs was critical to the success …

Mohamed Abou-el-Enein named Executive Director of USC/CHLA Cell Therapy Program

Mohamed Abou-el-Enein, MD, PhD, MSPH, has joined the Keck School of Medicine as the inaugural Executive Director of the Joint USC/CHLA Cell Therapy Program. He began his post Jan. 4. Abou-el-Enein will also serve as Medical Director of the new cGMP facility for cell and gene therapy that is under construction in the Norris Research …

Fraser by Noe Montes

USC biological imaging innovator elected to National Academy of Medicine

Scott Fraser, Provost Professor of Biological Sciences, Biomedical Engineering, Physiology and Biophysics, Stem Cell Biology and Regenerative Medicine, Pediatrics, Radiology and Ophthalmology, has been elected to the National Academy of Medicine. Fraser, who holds joint appointments at the USC Dornsife College of Letters, Arts and Sciences and USC Viterbi School of Engineering as well as …

Wilms tumor team

A bench-to-bedside approach to Wilms tumor

Stefano Da Sacco, PhD, calls Wilms tumor “an underdog” in the research world. “If you go to the American Urological Association or other meetings, there aren’t many presentations or discussions about Wilms tumor,” Dr. Da Sacco says. “From my experience, it’s understudied. Not many basic scientists are working on it.” It’s a different story at …

Scott E. Fraser

USC’s Scott E. Fraser elected to National Academy of Medicine

USC biophysicist Scott E. Fraser, PhD, has as been elected to the National Academy of Medicine, the organization announced Monday. He’s among 100 new members of the Academy. “For integrating biophysics, quantitative biology, and molecular imaging to enable unprecedented views of normal function and disease in live organisms, from embryonic development to old age,” the …

Ebony Flowers

Ebony Flowers receives fellowship from the Burroughs Wellcome Fund Postdoctoral Enrichment Program

Ebony Flowers has already received three fellowships during her year-and-a-half as a postdoctoral fellow in the Department of Stem Cell Biology and Regenerative Medicine at USC. First, she was awarded the Choi Family Postdoctoral Fellowship, which helped recruit her to Min Yu’s laboratory. Then she earned a fellowship from the A.P. Giannini Foundation, which provided …

fasting and breast cancer

Studies suggest a fasting diet could boost breast cancer therapy

A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans. In studies on mice and in two small breast cancer clinical trials, researchers at USC and the IFOM Cancer Institute …

Men are from Mars

New award supports study of why females age differently than males

A new research project led by USC Leonard Davis School of Gerontology Assistant Professor Bérénice Benayoun aims to learn more about why female mammals, including humans, age differently than males. Sex dimorphism – physiological characteristics that differ between the sexes in a species – can have big implications for health and lifespan. Human longevity differs …

Alec Fisher

Amid COVID-19 fears, USC Spirit Leader donates stem cells for leukemia patient

When Alec Fisher signed up as a potential bone marrow donor two years ago, he didn’t expect to hear back for a while, if at all — and certainly not in the middle of a pandemic. As someone who has had personal experiences with serious health issues, Fisher felt a calling to donate. When he …

Qi-Long Ying

Shanghai Cell Therapy Group launches collaboration with USC researcher to improve the ex vivo expansion of hematopoietic stem cells for clinical applications

Shanghai Cell Therapy Group (SHCell) recently entered into a six-year research collaborative project with Professor Qi-Long Ying from the University of Southern California (USC). Through the project, sponsored by $3.6 million from the Baize Plan Fund, the Ying laboratory aims to develop conditions for the long-term ex vivo expansion of mouse and human hematopoietic stem …

Rong Lu

USC Stem Cell scientist Rong Lu wins an NIH Emerging Investigator Award

Millions of blood cells are regenerated every second. To study the unique properties of individual blood forming stem cells and how they contribute to aging, leukemia and other medical conditions, USC Stem Cell scientist Rong Lu has received a $6.6 million Emerging Investigator Award from National Heart, Lung, and Blood Institute (NHLBI), which is part …

Photo by Isaac Mora

Better cancer treatments may lie ahead thanks to Yong (Tiger) Zhang and USC engineers

A USC School of Pharmacy-led team has engineered a new, faster way to make drugs that precisely target malignant cells – while leaving healthy tissue undamaged – that could lead the way to better treatments for numerous types of cancer. The drugs, called antibody-drug conjugates or ADCs, belong to a relatively new class in which …

Oranges

Fasting plus vitamin C proves effective for hard-to-treat cancers

Scientists from USC and the IFOM Cancer Institute in Milan have found that a fasting-mimicking diet could be more effective at treating some types of cancer when combined with vitamin C. In multiple studies on mice, researchers found that the combination delayed tumor progression in multiple mouse models of colorectal cancer; in some mice, it caused …

Min Yu (Photo by Chris Shinn)

USC Stem Cell scientist Min Yu awarded Era of Hope Scholar Award from the U.S. Department of Defense for breast cancer research

Most breast cancer cells won’t kill you. It is the rare cell that can survive the perilous journey through the bloodstream and seed the metastatic lesions responsible for the vast majority of breast cancer-related deaths. And although these rare cancer cells are difficult to find and even harder to study in the lab, they have …

Andrew P. McMahon

USC Professor Andrew P. McMahon elected to the National Academy of Sciences

Andrew P. McMahon—who is the W.M. Keck Provost and University Professor in USC’s departments of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine, and Biological Sciences at the Dornsife College of Letters, Arts and Sciences—has been elected as a new member of the National Academy of Sciences in honor of his …

Long Cai

The Broad Foundation brings together stem cell scientists, engineers and physicians at USC and beyond

Developing new stem cell therapies requires more than a solo biologist having a eureka moment alone in the lab. Real progress relies on collaborations between biologists, engineers and physicians. That’s why The Eli and Edythe Broad Foundation has continued its support of two strategic initiatives: innovation awards bringing together teams of engineers and scientists from …

Ebony Flowers

USC Stem Cell scientist Ebony Flowers earns fellowship from the A.P. Giannini Foundation

From goji berries to green tea, antioxidant rich superfoods are celebrated for protecting against cancer-causing free radicals. But what is the role of free radicals—and the process of cell metabolism that produces free radicals—in patients who have already been diagnosed with breast cancer? USC Stem Cell postdoctoral fellow Ebony Flowers will address this question with …

Time to eat

What and when we eat affects our immune system. Here’s how.

Professor Valter Longo, director of the USC Longevity Institute, is investigating how fasting and diets that mimic fasting’s effects can help immune function, including vaccine efficacy and the body’s response to infection by viruses such as influenza and eventually COVID-19. Fasting and fasting mimicking diets appear to “get rid of damaged or mis­guided cells and …

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