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USC Stem Cell scientists explore the latent regenerative potential of the inner ear

Scientists from the USC Stem Cell laboratory of Neil Segil have identified a natural barrier to the regeneration of the inner ear’s sensory cells, which are lost in hearing and balance disorders. Overcoming this barrier may be a first step in returning inner ear cells to a newborn-like state that’s primed for regeneration, as described …

Study highlights differences in immune cell function between male and female mice

A new USC study of a common, yet poorly understood type of white blood cell reveals the human immune cell’s response to pathogens differs greatly by sex and by age.  In this mouse study, males proved much more susceptible to a condition called sepsis than females. However, the scientists also found that the female disease-defense system is hardly perfect; their system changes with age to become nearly as harmful as the males’.    Those are the key findings in a study that appeared July 19, 2021 in Nature Aging.   …

USC Professor Scott E. Fraser redefines impossible problems

USC Professor Scott E. Fraser is known for inventing new microscopes and other tools to observe living, developing embryos. But one of his lab’s most important pieces of technology filters coffee instead of light: it’s a restaurant-quality Espresso machine. “I wanted to make a place where people would come to steal coffee,” he said. “And …

USC Professor Megan McCain crafts an approach to tissue engineering

Megan McCain has always liked using her hands to create things, ranging from art projects to human heart cells that grow on silicon chips. “I’ve always loved building things and doing crafts, which drew me to engineering,” said McCain, who was recently awarded tenure as an Associate Professor and the Chonette Early Career Chair in …

Bérénice Benayoun receives GSA Nathan Shock New Investigator Award

The Gerontological Society of America (GSA)—the nation’s largest interdisciplinary organization devoted to the field of aging—has chosen Assistant Professor Bérénice Benayoun of the USC Leonard Davis School of Gerontology as the 2021 recipient of the Nathan Shock New Investigator Award. The distinguished honor is given for outstanding contributions to new knowledge about aging through basic …

Call for Applications: T32 Fellowships in Developmental Biology, Stem Cells, and Regeneration

All PhD students who are conducting research related to developmental biology, stem cell biology, and/or regenerative medicine are encouraged to apply for a training fellowship. We have several slots available for both U.S. Citizens and international students, and funding will be for one year with a second year dependent on participation in program activities and …

The same cell type can help or hinder repair after acute kidney injury

The USC Stem Cell laboratory of Andy McMahon has identified a type of injured cell that might contribute to the transition from an acute kidney injury to chronic kidney disease, as described in a new study published in the Proceedings of the National Academy of Sciences (PNAS). The same issue of PNAS also features an …

The Baxter Foundation advances USC research on optic nerve disease and colorectal cancer

For over 60 years, the Donald E. and Delia B. Baxter Foundation has supported innovative biomedical research at the Keck School of Medicine of USC, each year granting $100,000 awards to two faculty members. This year, the Baxter Foundation awarded Kimberly Gokoffski, MD, PhD, Assistant Professor of Clinical Ophthalmology at the USC Roski Eye Institute, …

USC Stem Cell scientists make big progress in building mini-kidneys

A team of scientists at the Keck School of Medicine of USC has created what could be a key building block for assembling a synthetic kidney. In a new study in Nature Communications, Zhongwei Li and his colleagues describe how they can generate rudimentary kidney structures, known as organoids, that resemble the collecting duct system …

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