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The kidney contains macula densa cells, which orchestrate kidney regeneration.; featured image for To regenerate the kidney, please don’t pass the salt

To regenerate the kidney, please don’t pass the salt

USC study showing loss of salt and body fluid stimulates kidney regeneration in mice, suggests new therapeutic approach to chronic kidney disease. A loss of salt and body fluid can stimulate kidney …

Christian Chung; featured image for Graduates of the Keck School of Medicine of USC’s master’s, doctoral, and nurse anesthesia programs go forth with “gwenchana”

Graduates of the Keck School of Medicine of USC’s master’s, doctoral, and nurse anesthesia programs go forth with “gwenchana”

At the Keck School of Medicine of USC’s 2024 Commencement Ceremony for the master’s, doctoral, and nurse anesthesia programs, the word of the day was “gwenchana.” “Today, I want to teach a …

(Photo by William Vasta); featured image for How the USC stem cell master’s program changed the lives of 10 alumni

How the USC stem cell master’s program changed the lives of 10 alumni

In honor of the 10th anniversary of USC’s stem cell master’s program, we asked 10 alumni to reflect on how the program changed the course of their lives and careers. Launched in …

Lab grown human nephron progenitor cells (Image by Biao Huang/Li Lab); featured image for USC-led study introduces a new and improved way to grow the cells that give rise to the kidney’s filtration system

USC-led study introduces a new and improved way to grow the cells that give rise to the kidney’s filtration system

In a new study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney’s filtration system, the nephrons. NPCs …

Organoid with neurons labeled in green (Image by Joshua Berlind/Ichida Lab); featured image for Organoids reveal how to protect the brain against dementia and ALS following traumatic injury, according to USC Stem Cell study

Organoids reveal how to protect the brain against dementia and ALS following traumatic injury, according to USC Stem Cell study

A traumatic brain injury (TBI) can quadruple your risk for developing dementia, and also increase your chances of developing neurodegenerative diseases such as ALS. In a new study published in Cell Stem …

Linda Sher; featured image for USC surgeon-scientist Linda Sher receives $2.7 million CIRM grant to develop and test immunologically modified and humanized swine livers

USC surgeon-scientist Linda Sher receives $2.7 million CIRM grant to develop and test immunologically modified and humanized swine livers

In 1992, Linda Sher was part of a surgical team at Cedars-Sinai that transplanted a pig liver into a human patient for the first time in the history of medicine. The pig …

Kidney organoids with proximal tubules (Image by Jack Schnell/Lindström Lab); featured image for $3.95 million CIRM grant establishes USC ASCEND Center to make stem cell-derived  organ models accessible to all

$3.95 million CIRM grant establishes USC ASCEND Center to make stem cell-derived organ models accessible to all

To democratize access to lab-grown organ-like structures known as organoids and other advanced stem cell and transcriptomic technologies, USC will launch the CIRM ASCEND Center, dedicated to “Advancing Stem Cell Education and …

Rong Lu (right) and Du Jiang (Photo by Gal Manella); featured image for USC Stem Cell study shows how gene activity modulates the amount of immune cell production in mice

USC Stem Cell study shows how gene activity modulates the amount of immune cell production in mice

As people age or become ill, their immune systems can become exhausted and less capable of fighting off viruses such as the flu or COVID-19. In a new mouse study funded in …

Oliver Bell and Daniel Bsteh; featured image for USC Stem Cell study throws our understanding of gene regulation for a loop

USC Stem Cell study throws our understanding of gene regulation for a loop

The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be …

Lab-grown 6-month-old human Purkinje cell (Image by Alexander Atamian and Marcella Birtele/Quadrato Lab); featured image for USC Stem Cell scientists develop a game-changing organoid model to study human cerebellar development and disease

USC Stem Cell scientists develop a game-changing organoid model to study human cerebellar development and disease

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that …

Building an Incubator for Medicine of the 21st Century; featured image for Building an Incubator for Medicine of the 21st Century

Building an Incubator for Medicine of the 21st Century

USC Stem Cell is pleased to introduce our new publication. We hope you’ll enjoy reflecting back on our history, while looking ahead to the transformative times to come. Read now at https://stemcell.keck.usc.edu/wp-content/themes/stemcell/incubator.

Two sculptures representing a human neuron and a radial glia cell, inspired by the findings published by the Quadrato Lab in Nature Neuroscience. (Sculptures by Jane Kwak; photo by Sergio Bianco); featured image for The Autism-linked gene SYNGAP1 could impact early stages of human brain development, USC study reveals

The Autism-linked gene SYNGAP1 could impact early stages of human brain development, USC study reveals

New research shows that variants of SYNGAP1, a gene previously thought only to affect synapses between mature neurons, may disrupt early development in the brain’s cortex, a region involved in higher-order cognitive …

(Photo by William Vasta); featured image for USC doubles the number of scholarships for stem cell master’s students

USC doubles the number of scholarships for stem cell master’s students

This year, ten students earned scholarships that enabled them to attend USC’s master’s program in stem cell biology and regenerative medicine, one of the only programs of its kind in the United …

Justin Ichida (Photo by Ben Gibbs); featured image for USC Stem Cell research from Justin Ichida’s lab advances toward clinical development for ALS, following a license agreement between companies Takeda and AcuraStem

USC Stem Cell research from Justin Ichida’s lab advances toward clinical development for ALS, following a license agreement between companies Takeda and AcuraStem

USC Stem Cell scientist Justin Ichida has learned to inhabit two worlds: the university where his lab makes discoveries, and the companies that can help commercialize these discoveries into new treatments for …

The 2023 Mammalian Synthetic Biology Workshop (Photo courtesy of Catcher Salazar); featured image for Three USC Stem Cell undergraduates expand their horizons, thanks to Neil Segil Travel Scholarships

Three USC Stem Cell undergraduates expand their horizons, thanks to Neil Segil Travel Scholarships

Few scientists will ever forget the first time they presented their research at a conference. Thanks to the Neil Segil Stem Cell Travel Scholarships, three USC Stem Cell undergraduate researchers recently experienced …

Two of the genes—Gsta4 in red and Cyp4a14 in green—that are more active in female mouse kidneys (blue) (Image by Jing Liu/McMahon Lab); featured image for Why are male kidneys more vulnerable to disease than female kidneys? USC Stem Cell-led mouse study points to testosterone.

Why are male kidneys more vulnerable to disease than female kidneys? USC Stem Cell-led mouse study points to testosterone.

Female kidneys are known to be more resilient to disease and injury, but males need not despair. A new USC Stem Cell-led study published in Developmental Cell describes not only how sex …

Neural stem cells derived from patients with ALS or frontotemporal dementia (Image by Eric Hendricks/Ichida Lab); featured image for ALS and frontotemporal dementia show origins in utero, according to evidence from mice and patient-derived stem cells

ALS and frontotemporal dementia show origins in utero, according to evidence from mice and patient-derived stem cells

Even though neurodegenerative diseases often strike in middle age or later, patients could have structural differences in their brains that arise before birth. In a new study in Cell Reports, USC Stem …

Rows of sensory hearing cells (green) next to supporting cells (red) in the inner ear of a mouse (Image by John Duc Nguyen and Juan Llamas/Segil Lab); featured image for USC Stem Cell mouse studies tune into hearing regeneration

USC Stem Cell mouse studies tune into hearing regeneration

A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don’t regenerate after damage. In two new studies, partially funded by the National Institutes …

Alma Zuniga Munoz and Albert Almada (Photo by Cristy Lytal); featured image for Stem Cell PhD student Alma Zuniga Munoz wins USC’s first Gilliam Fellowship from the Howard Hughes Medical Institute

Stem Cell PhD student Alma Zuniga Munoz wins USC’s first Gilliam Fellowship from the Howard Hughes Medical Institute

Alma Zuniga Munoz, a student in USC’s PhD program in Development, Stem Cells, and Regeneration, is used to being the first. She’s a first-generation American, the first member of her extended family …

At the lab bench (Photo by Chris Shinn); featured image for Ten USC Stem Cell PhD students and recent graduates earn NIH fellowships

Ten USC Stem Cell PhD students and recent graduates earn NIH fellowships

Ten USC Stem Cell PhD students and recent graduates have been awarded fellowships from the National Institutes of Health (NIH). Known as F31 awards, these prestigious fellowships provide promising PhD students with …