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3-D printed Cas9 enzyme that snips a DNA sequence at a location identified by CRISPR. (Photo courtesy of the NIH 3D Print Exchange, National Institutes of Health)

USC Stem Cell scientists enter the conversation about CRISPR

CRISPR-Cas9 is a gene-editing technique that enables scientists to disable, replace or modify sections of DNA. It allows for unprecedented precision and speed in the field of genome editing. It has been used to …

Qi-Long Ying (Photo by Cristy Lytal)

Scientists Qi-Long Ying and Austin Smith win the 2016 McEwen Award for Innovation

Video by Henry Liu Researchers Qi-Long Ying from USC and Austin Smith from the University of Cambridge have won the 2016 McEwen Award for Innovation, the highest honor bestowed by the International …

From right, Qi-Long Ying, director of the Chang Stem Cell Engineering Facility; Daniel Chang; Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC; and Cai Li Chang (Photo by Cristy Lytal)

Chang Stem Cell Engineering Facility brings gene editing to USC and beyond

Once the stuff of science fiction, genetic engineering is now offered on a fee-for-service basis at USC. On September 19, USC Stem Cell faculty and staff welcomed their supporters, the Chang and …

USC PhD student Louise Menendez examines the prototype of a potential device to treat patients with liver disease. (Photo by Cristy Lytal)

“Million-dollar ideas” seminar

At a special seminar on February 24, USC Stem Cell Principal Investigators discussed their “million-dollar ideas” for creating new tools and technologies to usher in the era of regenerative medicine. They shared …

From left, Toshio Miki, Qi-Long Ying, Paula Cannon (Photos by Cristy Lytal and Don Milici)

Three USC researchers win $4.3 million in awards from California’s stem cell agency

Three scientists from Keck Medicine of USC have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine (CIRM) for research that includes creating a temporary liver for patients, finding …

“Tin Woman” Michaela Patterson, a postdoctoral scholar in the lab of Henry Sucov, studies heart regeneration — with no help from the Wizard of Oz. (Photo by Cristy Lytal)

Halloween retreat showcases USC’s “scary smart” stem cell researchers

It was no tricks and all treats at the seventh annual retreat for the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, held at the university’s …

Keynote speaker Clive Svendsen (right) and Director Andy McMahon

A Retreat from everything but stem cells

It wasn’t the pristine 27-hole course that drew more than 120 stem cell researchers from USC and beyond to the Desert Princess Golf Resort near Palm Springs. It was the sixth annual …

Embryonic stem cells (Image/courtesy of Qi-Long Ying)

USC researcher reveals how to better master stem cells’ fate

USC scientist Qi-Long Ying and a team of researchers have long been searching for biotech’s version of the fountain of youth — ways to encourage embryonic stem cells (ESCs) and epiblast stem …

From left, Andrew P. McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, with Yong Chen’s son Gary and researcher Qi-Long Ying (Photo by Cristy Lytal)

Businessman invests in stem cell research at USC

Chinese businessman Yong Chen has pledged $1 million to USC stem cell researcher Qi-Long Ying to support his future “eureka moments.” “When I talked to Mr. Chen, I told him that groundbreaking …

Neural stem cells derived from self-renewing mouse embryonic stem cells (Image courtesy of Qi-Long Ying)

A special protein helps embryonic stem cells keep their options open

In the ongoing quest to understand how embryonic stem cells (ESCs) retain their ability to differentiate into virtually any kind of cell, USC faculty member Qi-Long Ying and a team of researchers …

Qi-Long Ying (Photo by Cristy Lytal)

A genetic catch-22 promotes and prevents liver cancer

Can the same gene prevent and promote cancer? When it comes to liver cancer, the gene that codes for P53, a protein found in humans and many other animals, involves this catch-22. …

Andy McMahon (Photo by Phil Channing)

Probing the power of stem cells

Piece by missing piece, scientists at the Keck School of Medicine of USC are deciphering the powerful gene regulatory circuit that maintains and controls the potential of embryonic stem cells (ESCs) to …

Dr. Qilong Ying (left) and USC graduate student Chih-I (Jimmy) Tai (Photo courtesy of USC)

An important factor identified in reprogramming

How is the stem cell state programmed? A new study in Qi-Long Ying’s group at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC highlights the role …

Qi-Long Ying (Photo by Cristy Lytal)

USC research listed among top breakthroughs of 2010

Groundbreaking research by Keck School of Medicine of USC researchers has been selected as one of Science magazine’s top 10 Breakthroughs of 2010. The study, Production of p53 gene knockout rats by …

Qi-Long Ying (Photo by Cristy Lytal)

USC researchers create first “knockout” rats using embryonic stem cell technology

Researchers at the Keck School of Medicine of the University of Southern California (USC) have, for the first time, generated “knockout” rats—animals that are genetically modified to lack one or more genes—through …

Qi-Long Ying, MD, PhD